Zobrazeno 1 - 10
of 722
pro vyhledávání: '"A.-L. Grosu"'
Autor:
F. Schiller, T. Fechter, C. Zamboglou, A. Chirindel, N. Salman, C.A. Jilg, V. Drendel, M. Werner, P.T. Meyer, A.-L. Grosu, M. Mix
Publikováno v:
EJNMMI Physics, Vol 4, Iss 1, Pp 1-15 (2017)
Abstract Background Implementation of PET/CT in diagnosis of primary prostate cancer (PCa) requires a profound knowledge about the tracer, preferably from a quantitative evaluation. Direct visual comparison of PET/CT slices to whole prostate sections
Externí odkaz:
https://doaj.org/article/c79c3f6ff6d240c78762a379358f9c74
Autor:
Athanasios Kafkaletos, Michael Mix, Ilias Sachpazidis, Montserrat Carles, Alexander Rühle, Juri Ruf, Anca L. Grosu, Nils H. Nicolay, Dimos Baltas
Publikováno v:
EJNMMI Physics, Vol 11, Iss 1, Pp 1-20 (2024)
Abstract Background The purpose of this study was to evaluate how a retrospective correction of the partial volume effect (PVE) in [18F]fluoromisonidazole (FMISO) PET imaging, affects the hypoxia discoverability within a gross tumour volume (GTV). Th
Externí odkaz:
https://doaj.org/article/9ee0dcb996904ccfa6fb5b162e2f27fd
Autor:
Karnika Singh, Chunhua Han, Jessica L. Fleming, Aline P. Becker, Joseph McElroy, Tiantian Cui, Benjamin Johnson, Ashok Kumar, Ebin Sebastian, Christian A. Showalter, Morgan S. Schrock, Matthew K. Summers, Valesio Becker, Zhen-yue Tong, Xiaomei Meng, Heather R. Manring, Monica Venere, Erica H. Bell, Pierre A. Robe, A. L. Grosu, S. Jaharul Haque, Arnab Chakravarti
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract GBM (Glioblastoma) is the most lethal CNS (Central nervous system) tumor in adults, which inevitably develops resistance to standard treatments leading to recurrence and mortality. TRIB1 is a serine/threonine pseudokinase which functions as
Externí odkaz:
https://doaj.org/article/782c8e1ac1a249059c785891953b7453
Autor:
Eleni Gkika, Elke Firat, Sonja Adebahr, Erika Graf, Ilinca Popp, Gianluca Radicioni, Simon S. Lo, Ursula Nestle, Nils H. Nicolay, Gabriele Niedermann, Dan G. Duda, Anca-L. Grosu
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract We performed a prospective study of circulating immune cell changes after stereotactic body radiotherapy (SBRT) in 50 early-stage NSCLC patients. We found no significant increase in CD8+ cytotoxic T lymphocytes at first follow-up (the primar
Externí odkaz:
https://doaj.org/article/537504b77a584db7a48979724411a17a
Autor:
Tun Wiltgen, Daniel F. Fleischmann, Lena Kaiser, Adrien Holzgreve, Stefanie Corradini, Guillaume Landry, Michael Ingrisch, Ilinca Popp, Anca L. Grosu, Marcus Unterrainer, Peter Bartenstein, Katia Parodi, Claus Belka, Nathalie Albert, Maximilian Niyazi, Marco Riboldi
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Background Quantitative image analysis based on radiomic feature extraction is an emerging field for survival prediction in oncological patients. 18F-Fluorethyltyrosine positron emission tomography (18F-FET PET) provides important diagnostic
Externí odkaz:
https://doaj.org/article/e106d8566b9c4fabaf1817fcdf04cdf4
Autor:
Ioana M. Marinescu, Manuel Rogg, Simon Spohn, Moritz von Büren, Marius Kamps, Cordula A. Jilg, Elena Fountzila, Kyriaki Papadopoulou, Lara Ceci, Alisa Bettermann, Juri Ruf, Matthias Benndorf, Sonja Adebahr, Daniel Zips, Anca L. Grosu, Christoph Schell, Constantinos Zamboglou
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-10 (2022)
Abstract Backround Accurate surrogate parameters for radio resistance are warranted for individualized radiotherapy (RT) concepts in prostate cancer (PCa). The purpose of this study was to assess intertumoral heterogeneity in terms of radio resistanc
Externí odkaz:
https://doaj.org/article/33c81c387e9a4b16b5dfaef6029b7aba
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Biologically younger, fully independent octogenarians are able to tolerate most oncological treatments. Increasing frailty results in decreasing eligibility for certain treatments, e.g., chemotherapy and surgery. Most brain metastases are not an isol
Externí odkaz:
https://doaj.org/article/85ac26ebb70643e8ae8de6ad7f311095
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Background and objectivesThe validated LabBM score (laboratory parameters in patients with brain metastases) represents a widely applicable survival prediction model, which incorporates 5 blood test results (serum lactate dehydrogenase (LDH), C-react
Externí odkaz:
https://doaj.org/article/6504891eba78491d82808a0601812c2f
Autor:
Alexander Rühle, Anca-L. Grosu, Nicole Wiedenmann, Juri Ruf, Birgit Bieber, Raluca Stoian, Andreas R. Thomsen, Eleni Gkika, Peter Vaupel, Dimos Baltas, Wolfgang A. Weber, Michael Mix, Nils H. Nicolay
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 33, Iss , Pp 120-127 (2022)
Background: Tumor hypoxia worsens the prognosis of head-and-neck squamous cell carcinoma (HNSCC) patients, and plasma hypoxia markers may be used as biomarkers for radiotherapy personalization. We therefore investigated the role of the hypoxia-associ
Externí odkaz:
https://doaj.org/article/609bfa9ad90f490aa4546f8f6f71895f
Autor:
S. K. B. Spohn, S. Adebahr, M. Huber, C. Jenkner, R. Wiehle, B. Nagavci, C. Schmucker, E. G. Carl, R. C. Chen, W. A. Weber, M. Mix, A. Rühle, T. Sprave, N. H. Nicolay, C. Gratzke, M. Benndorf, T. Wiegel, J. Weis, D. Baltas, A. L. Grosu, C. Zamboglou
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Objective Failure rate in randomized controlled trials (RCTs) is > 50%, includes safety-problems, underpowered statistics, lack of efficacy, lack of funding or insufficient patient recruitment and is even more pronounced in oncology trials.
Externí odkaz:
https://doaj.org/article/4df0f24edbe84ea191fc61feb426fbb3