Zobrazeno 1 - 10
of 76
pro vyhledávání: '"A.-K. Vartiainen"'
Publikováno v:
European Psychiatry, Vol 65, Pp S293-S293 (2022)
Introduction Digital mental health interventions, such as chatbots that promote mental health and wellbeing are a promising way to deliver low-threshold support 24/7 for those in need. According to current knowledge about the topic, health care profe
Externí odkaz:
https://doaj.org/article/58ade268aee84c9985bc11f37507f043
Autor:
A.-K. Vartiainen, V. Kuvaja-Köllner, M. Rantsi, E. Rissanen, T. Luntamo, M. Kurki, A. Sourander, E. Kankaanpää
Publikováno v:
European Psychiatry, Vol 65, Pp S684-S684 (2022)
Introduction Anxiety disorders are common in children and youth. Also, in prevention, be it universal, selective or indicated, economic evaluation supports decision-making in the allocation of scarce resources. Objectives This review identified and
Externí odkaz:
https://doaj.org/article/a01b23034179446fb9926381fd4f7418
Autor:
L. Kuosmanen, A.-K. Vartiainen, H. Nieminen, C. Kostenius, R. Bond, M. Mulvenna, C. Potts, E. Ennis, M. Malcolm, A. Vakaloudis, B. Cahill, I. Dhanapala
Publikováno v:
European Psychiatry, Vol 65, Pp S168-S168 (2022)
Introduction In many countries, people face problems regarding access to care, 24/7 support and evidence-based support. Digital interventions and services, such as chatbots, can be one option to tackle these challenges. There is a lack knowledge rega
Externí odkaz:
https://doaj.org/article/50c5f7df637a44eba72add856f6eecd1
Autor:
Ekaterina Sidorenko, Maria Sokolova, Antti P. Pennanen, Salla Kyheröinen, Guido Posern, Roland Foisner, Maria K. Vartiainen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Myocardin-related transcription factor A (MRTF-A), a coactivator of serum response factor (SRF), regulates the expression of many cytoskeletal genes in response to cytoplasmic and nuclear actin dynamics. Here we describe a novel mechanism to
Externí odkaz:
https://doaj.org/article/02ab6360286c47dc8cfc463a97d95cc7
Autor:
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 11, Pp 1-26 (2021)
Abstract Treatment options for COVID‐19, caused by SARS‐CoV‐2, remain limited. Understanding viral pathogenesis at the molecular level is critical to develop effective therapy. Some recent studies have explored SARS‐CoV‐2–host interactome
Externí odkaz:
https://doaj.org/article/c87ddbd7671244cc9c1ca8b5b5555d62
Autor:
Taras A. Redchuk, Maksim M. Karasev, Polina V. Verkhusha, Sara K. Donnelly, Maren Hülsemann, Jori Virtanen, Henna M. Moore, Maria K. Vartiainen, Louis Hodgson, Vladislav V. Verkhusha
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Optogenetic approaches to control protein-protein interactions usually require overexpression of the target proteins. Here the authors integrate intrabodies into near-infrared- and blue-light activatable optogenetic tools to control endogenous protei
Externí odkaz:
https://doaj.org/article/6f20a13284cc4e2a9ddb3638c37c57ca
Autor:
Maria Sokolova, Henna M. Moore, Bina Prajapati, Joseph Dopie, Leena Meriläinen, Mikko Honkanen, Rita Cerejeira Matos, Minna Poukkula, Ville Hietakangas, Maria K. Vartiainen
Publikováno v:
iScience, Vol 9, Iss , Pp 63-70 (2018)
Summary: Actin has been linked to processes spanning the whole gene expression cascade, from regulating specific transcription factors, such as myocardin-related transcription factor, to chromatin remodeling and RNA polymerase function. However, whet
Externí odkaz:
https://doaj.org/article/0377805f70d5493dbdd210059f1f9fdb
Autor:
Maria Sokolova, Maria K. Vartiainen
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629697
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42e744bbf9d7ffda61e622427637c189
https://doi.org/10.1007/978-1-0716-2970-3_18
https://doi.org/10.1007/978-1-0716-2970-3_18
Autor:
Mette Ilander, Vincenzo Cerullo, Maria Sokolova, Susanna C. Fagerholm, Imrul Faisal, Robert Tallberg, Maria K. Vartiainen, Jose-Maria Gonzalez-Granado, Heidi Harjunpää, Carla Guenther, Ronen Alon, Manlio Fusciello
Publikováno v:
Cancer Immunology Research
Dendritic cells (DC), the classic antigen-presenting cells of the immune system, switch from an adhesive, phagocytic phenotype in tissues, to a mature, nonadhesive phenotype that enables migration to lymph nodes to activate T cells and initiate antit
Autor:
Salla Kyheröinen, Maria K. Vartiainen
Publikováno v:
Seminars in Cell & Developmental Biology. 102:105-112
Although best known from its functions in the cytoplasm, actin also localizes to the cell nucleus, where it has been linked to many essential functions from regulation of gene expression to maintenance of genomic integrity. While majority of cytoplas