Zobrazeno 1 - 10
of 5 570
pro vyhledávání: '"A. van Laarhoven"'
Autor:
Kolmus, Alex, Janquart, Justin, Baka, Tomasz, van Laarhoven, Twan, Broeck, Chris Van Den, Heskes, Tom
Modern simulation-based inference techniques use neural networks to solve inverse problems efficiently. One notable strategy is neural posterior estimation (NPE), wherein a neural network parameterizes a distribution to approximate the posterior. Thi
Externí odkaz:
http://arxiv.org/abs/2403.02443
Autor:
Vazifehdoostirani, Mozhgan, Genga, Laura, Lu, Xixi, Verhoeven, Rob, van Laarhoven, Hanneke, Dijkman, Remco
Process pattern discovery methods (PPDMs) aim at identifying patterns of interest to users. Existing PPDMs typically are unsupervised and focus on a single dimension of interest, such as discovering frequent patterns. We present an interactive multi
Externí odkaz:
http://arxiv.org/abs/2308.14475
Autor:
L. A. Daamen, I. W. J. M. van Goor, V. P. Groot, P. C. M. Andel, L. A. A. Brosens, O. R. Busch, G. A. Cirkel, N. Haj Mohammad, H. D. Heerkens, I. H. J. T. de Hingh, F. Hoogwater, H. W. M. van Laarhoven, M. Los, G. J. Meijer, V. E. de Meijer, R. Pande, K. J. Roberts, J. Stoker, M. W. J. Stommel, G. van Tienhoven, R. C. Verdonk, H. M. Verkooijen, F. J. Wessels, J. W. Wilmink, M. G. Besselink, H. C. van Santvoort, M. P. W. Intven, I. Q. Molenaar, for the Dutch Pancreatic Cancer Group
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Disease recurrence remains one of the biggest concerns in patients after resection of pancreatic ductal adenocarcinoma (PDAC). Despite (neo)adjuvant systemic therapy, most patients experience local and/or distant PDAC recurrence w
Externí odkaz:
https://doaj.org/article/ba5d1663657942199349b99fc6296573
Autor:
Amber P. van der Zalm, Mark P. G. Dings, Paul Manoukian, Hannah Boersma, Reimer Janssen, Peter Bailey, Jan Koster, Danny Zwijnenburg, Richard Volckmann, Sanne Bootsma, Cynthia Waasdorp, Monique van Mourik, Dionne Blangé, Tom van den Ende, César I. Oyarce, Sarah Derks, Aafke Creemers, Eva A. Ebbing, Gerrit K. Hooijer, Sybren L. Meijer, Mark I. van Berge Henegouwen, Jan Paul Medema, Hanneke W. M. van Laarhoven, Maarten F. Bijlsma
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-11 (2024)
Abstract Background Despite the advent of neoadjuvant chemoradiotherapy (CRT), overall survival rates of esophageal adenocarcinoma (EAC) remain low. A readily induced mesenchymal transition of EAC cells contributes to resistance to CRT. Methods In th
Externí odkaz:
https://doaj.org/article/d7fc9df802d34addb7ab614129c458e9
Autor:
Dajia Liu, Amber P. van der Zalm, Jan Koster, Sanne Bootsma, Cesar Oyarce, Hanneke W.M. van Laarhoven, Maarten F. Bijlsma
Publikováno v:
Pharmacological Research, Vol 207, Iss , Pp 107315- (2024)
Epithelial-mesenchymal transition (EMT) has been identified as a driver of therapy resistance, particularly in esophageal adenocarcinoma (EAC), where transforming growth factor beta (TGF-β) can induce this process. Inhibitors of TGF-β may counterac
Externí odkaz:
https://doaj.org/article/693617776d904183909d7cef03180eb3
Autor:
Dajia Liu, Lihui Guo, Cynthia Waasdorp, Sybren L. Meijer, Sanne Bootsma, Cesar Oyarce, Maarten F. Bijlsma, Hanneke W.M. van Laarhoven
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117261- (2024)
Background: Long-term anti-angiogenesis leads to pruned vasculature, densely deposited extracellular matrix (ECM), and consequently reduced chemotherapy delivery in esophagogastric cancer (EGC). To address this issue, we evaluated the efficacy of add
Externí odkaz:
https://doaj.org/article/4443b6f6d2ae4872bc3299247fbd9f68
Autor:
Gabriela Singh, Arjan van Laarhoven, Rozanne Adams, Timothy Dawson Reid, Jill Combrinck, Suzanne van Dorp, Catherine Riou, Nqobile Thango, Johannes Enslin, Stefan Kruger, Anthony Aaron Figaji, Ursula Karin Rohlwink
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The pauci-cellular nature of cerebrospinal (CSF), particularly ventricular CSF, and the rapid cell death following sampling, incumbers the use of flow cytometric analysis of these samples in the investigation of central nervous system (CNS)
Externí odkaz:
https://doaj.org/article/f01252b7e89c4362b1c1a8b8494e95f6
Autor:
L. A. Daamen, I. W. J. M. van Goor, V. P. Groot, P. C. M. Andel, L. A. A. Brosens, O. R. Busch, G. A. Cirkel, N. Haj Mohammad, H. D. Heerkens, I. H. J. T. de Hingh, F. Hoogwater, H. W. M. van Laarhoven, M. Los, G. J. Meijer, V. E. de Meijer, R. Pande, K. J. Roberts, J. Stoker, M. W. J. Stommel, G. van Tienhoven, R. C. Verdonk, H. M. Verkooijen, F. J. Wessels, J. W. Wilmink, M. G. Besselink, H. C. van Santvoort, M. P. W. Intven, I. Q. Molenaar, for the Dutch Pancreatic Cancer Group
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/df249c70ed7544c39ba98d65b3adf85a
Autor:
Charlotte I. Stroes, Sybren L. Meijer, Geert-Jan Creemers, Gerrit K.J. Hooijer, Nadia Haj Mohammad, Maartje Los, Marije Slingerland, Geke A.P. Hospers, Annemieke Cats, Laurens V. Beerepoot, Maarten F. Bijlsma, Hanneke W.M. van Laarhoven
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102079- (2024)
Background: HER2 targeting in esophageal adenocarcinoma (EAC) has shown potential, but often fails to show durable response. Given the contributions of the tumor immune microenvironment (TIME) to therapeutic responses, we aimed to chart the TIME char
Externí odkaz:
https://doaj.org/article/140bcec5bc5649c49d43672c34967d9a
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.