Zobrazeno 1 - 10
of 41
pro vyhledávání: '"A. Yu. Shchegolev"'
Publikováno v:
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 20, Iss 1, Pp 56-60 (2024)
Aim of investigation. To estimate various variants of surgical treatment of acute biliary pancreatitis at patients of over 60 years old, to develop a method of cholecystectomy at the large Hartmann pouch adherent to biliary tracts, to decrease such c
Externí odkaz:
https://doaj.org/article/c1b54978c51c4f98bd4aec3e749f31bb
Autor:
Andrey I. Chavga, Oleg V. Midlenko, Vladimir I. Midlenko, Viktor A. Besov, Vladimir Yu. Shchegolev
Publikováno v:
Consilium Medicum, Vol 26, Iss 5, Pp 295-302 (2024)
Background. Over the past 10–15 years, there has been a clear trend towards improving the diagnosis and treatment of acute pancreatitis. However, even at the current stage of technology development, a number of difficulties arise in making an accur
Externí odkaz:
https://doaj.org/article/f2f602e86c124709b62ac6a49a8c61f7
Autor:
O. E. Andreeva, D. V. Sorokin, S. V. Vinokurova, Yu. Yu. Shchegolev, N. V. Elkina, A. N. Katargin, R. S. Faskhutdinov, D. I. Salnikova, A. M. Scherbakov, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 4, Pp 149-156 (2023)
Introduction. Rearrangement of molecular pathways and activation of bypass signaling determine the progression of tumor cell resistance to various drugs. Study of the common features of resistant formation mechanisms is essential for breast and other
Externí odkaz:
https://doaj.org/article/e6ac69de32684d978a782743306a0325
Autor:
Yu. Yu. Shchegolev, M. A. Karpukhina, D. V. Sorokin, A. M. Scherbakov, O. E. Andreeva, V. E. Razuvaeva, T. A. Bogush, I. N. Mikhaylova, L. V. Demidov, M. V. Gudkova, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 3, Pp 50-58 (2023)
Introduction. Melanoma belongs to the group of the most malignant tumors characterized by aggressive growth and active metastasis. At the same time, the effectiveness of therapy, primarily targeted therapy, is largely limited by the rapid development
Externí odkaz:
https://doaj.org/article/94aa493afae74c17a55cd214163d9cbc
Autor:
Yuri Yu. Shchegolev, Danila V. Sorokin, Alexander M. Scherbakov, Olga E. Andreeva, Diana I. Salnikova, Ekaterina I. Mikhaevich, Margarita V. Gudkova, Mikhail A. Krasil’nikov
Publikováno v:
BioImpacts, Vol 13, Iss 4, Pp 313-321 (2023)
Introduction: Resistance to chemotherapy and/or irradiation remains one of the key features of malignant tumors, which largely limits the efficiency of antitumor therapy. In this work, we studied the progression mechanism of breast cancer cell resist
Externí odkaz:
https://doaj.org/article/beb324107022466888a107ab710c0b69
Autor:
D. V. Sorokin, O. E. Andreeva, E. I. Mikhaevich, Yu. Yu. Shchegolev, A. M. Scherbakov, M. V. Gudkova, M. A. Krasil’nikov
Publikováno v:
Успехи молекулярной онкологии, Vol 7, Iss 3, Pp 58-62 (2020)
The most effective treatment of the hormone-dependent breast cancer is based on the antiestrogens SERM and aromatase inhibitor treatment, however its efficiency is limited by the acquired resistance to the drugs.Previously we have revealed the effect
Externí odkaz:
https://doaj.org/article/a85876f2fe654ccc96ea9c4033542666
Autor:
Yuri A. Piven, Veronica G. Zinovich, Tatyana S. Khlebnicova, Margarita A. Yastrebova, Anton E. Matous, Danila V. Sorokin, Alexander M. Scherbakov, Yuri Yu. Shchegolev, Fedor A. Lakhvich
Publikováno v:
Organicbiomolecular chemistry. 19(47)
Effective method of synthesis of 8-aryl-4,5-dihydrothiazolo[4',5':3,4]benzo[1,2-c]isoxazol-2-amines was developed. The method includes α-keto bromination of 3-aryl-6,7-dihydrobenzo[c]isoxazol-4(5H)-ones followed by condensation of obtained bromo der
Autor:
Mikhail A. Krasil'nikov, Danila V. Sorokin, Marina V. Nemtsova, Alexander M. Scherbakov, Olga E. Andreeva, Margarita V Gudkova, Yuri Yu. Shchegolev, Ekaterina I Mikhaevich, Irina V. Bure
Publikováno v:
Molecules
Molecules, Vol 26, Iss 6661, p 6661 (2021)
Molecules, Vol 26, Iss 6661, p 6661 (2021)
Hormone therapy is one of the most effective breast cancer treatments, however, its application is limited by the progression of hormonal resistance, both primary or acquired. The development of hormonal resistance is caused either by an irreversible
Autor:
Alexander M. Scherbakov, Mikhail A. Krasil'nikov, Danila V. Sorokin, Marina V. Nemtsova, Ekaterina B. Kuznetsova, Yuri Yu. Shchegolev, Ekaterina I Mikhaevich, Margarita V Gudkova, Olga E. Andreeva, Irina V. Bure, Dmitry V. Bagrov, Dmitry S. Mikhaylenko
Publikováno v:
Molecules, Vol 26, Iss 2499, p 2499 (2021)
Molecules
Molecules
Exosomes are the small vesicles that are secreted by different types of normal and tumour cells and can incorporate and transfer their cargo to the recipient cells. The main goal of the present work was to study the tumour exosomes’ ability to accu
Autor:
Danila V. Sorokin, Alexander M. Scherbakov, Margarita V Gudkova, Yuri Yu. Shchegolev, Oxana Ryabaya, Mikhail A. Krasil'nikov, Lev M. Berstein
Publikováno v:
Pharmaceuticals
Volume 13
Issue 9
Pharmaceuticals, Vol 13, Iss 206, p 206 (2020)
Volume 13
Issue 9
Pharmaceuticals, Vol 13, Iss 206, p 206 (2020)
The phenomenon of the primary or acquired resistance of cancer cells to antitumor drugs is among the key problems of oncology. For breast cancer, the phenomenon of the resistance to hormonal or target therapy may be based on the numerous mechanisms i