Zobrazeno 1 - 10
of 26
pro vyhledávání: '"A. Yu. Rotov"'
Autor:
Angelina V. Chirinskaite, Alexander Yu. Rotov, Mariia E. Ermolaeva, Lyubov A. Tkachenko, Anastasia N. Vaganova, Lavrentii G. Danilov, Ksenia N. Fedoseeva, Nicolay A. Kostin, Julia V. Sopova, Michael L. Firsov, Elena I. Leonova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17180 (2023)
Many retinal degenerative diseases result in vision impairment or permanent blindness due to photoreceptor loss or dysfunction. It has been observed that Pde6brd1 mice (rd1), which carry a spontaneous nonsense mutation in the pde6b gene, have a stron
Externí odkaz:
https://doaj.org/article/54aac568102f4810b41b906f5109c84d
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Vertebrate rods and cones operate over a wide range of ambient illumination, which is provided by light adaptation mechanisms regulating the sensitivity and speed of the phototransduction cascade. Three calcium-sensitive feedback loops are well estab
Externí odkaz:
https://doaj.org/article/4372a74d31c14b42a1cc2d2657c44ec5
Autor:
Alexander Yu. Rotov, Arsenii A. Goriachenkov, Roman V. Cherbunin, Michael L. Firsov, Nikita Chernetsov, Luba A. Astakhova
Publikováno v:
Cells, Vol 11, Iss 19, p 3056 (2022)
The avian magnetic compass allows orientation during migration and is shown to function properly under short-wavelength but not long-wavelength visible light. Therefore, the magnetoreceptive system is assumed to be light- and wavelength-dependent and
Externí odkaz:
https://doaj.org/article/65d8ba904b124f5a95d4cb1be1b9dcd3
Autor:
Alexander Yu Rotov, Roman V Cherbunin, Anna Anashina, Kirill V Kavokin, Nikita Chernetsov, Michael L Firsov, Luba A Astakhova
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229142 (2020)
Migratory birds can detect the direction of the Earth's magnetic field using the magnetic compass sense. However, the sensory basis of the magnetic compass still remains a puzzle. A large body of indirect evidence suggests that magnetic compass in bi
Externí odkaz:
https://doaj.org/article/7da0fa78c5de4fcdb2d448139d510036
Autor:
Luba A. Astakhova, Artem D. Novoselov, Maria E. Ermolaeva, Michael L. Firsov, Alexander Yu. Rotov
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13400 (2021)
Green rods (GRs) represent a unique type of photoreceptor to be found in the retinas of anuran amphibians. These cells harbor a cone-specific blue-sensitive visual pigment but exhibit morphology of the outer segment typical for classic red rods (RRs)
Externí odkaz:
https://doaj.org/article/bc56af253ea54309ab88239738a4c0cf
Autor:
A. Yu. Rotov, M. L. Firsov
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 58:1675-1686
Abstract Although the experience of optogenetic retinal prosthetics in animal models dates back to more than 16 years, the first results obtained on humans have only been reported in the last year. Over this period, the main challenges of prosthetics
Publikováno v:
Integrative Physiology. 3:233-245
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 57:1333-1350
Publikováno v:
Neuroscience and Behavioral Physiology. 51:807-815
The standard model system for studies of inherited retinal pathologies consists of C3H mice, which have a mutation in the Pde6b gene. These animals show impairment to the functioning of rod phosphodiesterase, leading to photoreceptor death and comple
Publikováno v:
Neuroscience and Behavioral Physiology. 51:116-122
The GPCR signal cascade in retinal photoreceptor cells – rods and cones – supports powerful signal amplification and allows rods to respond reliably to single light quanta. Rods remain functional at light fluxes down to 105 quanta/sec, which is s