Tumor microenvironment parameters as a predictor of the duration of clinical effectiveness of immunotargeted therapy in advanced or metastatic endometrial cancer: A pilot multicenter observational study

Autor: A. A. Maltseva, A. Yu. Kalinchuk, N. V. Krakhmal, N. M. Chernorubashkina, E. S. Martynova, R. A. Zukov, A. A. Gofman, A. B. Villert, O. N. Churuksaeva, L. A. Kolomiets, L. A. Tashireva

Publikováno v: Опухоли женской репродуктивной системы, Vol 20, Iss 1, Pp 114-123 (2024)

Background. The inclusion of lenvatinib in the immunotherapy regimen for patients with MSS/pMMR endometrial cancer (EC) is due to its ability to modulate the tumor microenvironment, which allows the use of pembrolizumab in low-immunogenic tumors. How

Externí odkaz: https://doaj.org/article/f6ff97e3ce1e4057a622dce54a5bf7d9

B Lymphocytes Are a Predictive Marker of Eribulin Response and Overall Survival in Locally Advanced or Metastatic Breast Cancer: A Multicenter, Two-Cohort, Non-Randomized, Open-Label, Retrospective Study

Autor: Liubov A. Tashireva, Nataliya O. Popova, Anna Yu. Kalinchuk, Viktor E. Goldberg, Elena I. Kovalenko, Elena V. Artamonova, Aleksey G. Manikhas, Dmitriy M. Ponomarenko, Nataliya V. Levchenko, Elena I. Rossokha, Svetlana Yu. Krasilnikova, Marina A. Zafirova, Evgeniy L. Choynzonov, Vladimir M. Perelmuter

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Triple-negative breast cancer has no specific treatment and unfavorable prognosis. Eribulin is one of the drugs widely used in this cohort of patients. In addition to its antimitotic effect, eribulin has an immunomodulant effect on the tumor microenv

Externí odkaz: https://doaj.org/article/3ac581e67d2b4694a111faae60feb03c

Characterization of EpCAM-Positive and EpCAM-Negative Tumor Cells in Early-Stage Breast Cancer.

Autor: Perelmuter, Vladimir M.¹ (AUTHOR), Grigoryeva, Evgeniya S.^2,3 (AUTHOR) grigoryeva.es@gmail.com, Alifanov, Vladimir V.¹ (AUTHOR), Kalinchuk, Anna Yu.² (AUTHOR), Andryuhova, Elena S.¹ (AUTHOR), Savelieva, Olga E.¹ (AUTHOR), Patskan, Ivan A.² (AUTHOR), Bragina, Olga D.⁴ (AUTHOR), Garbukov, Evgeniy Yu.⁵ (AUTHOR), Vostrikova, Mariya A.⁵ (AUTHOR), Zavyalova, Marina V.¹ (AUTHOR), Denisov, Evgeny V.⁶ (AUTHOR), Cherdyntseva, Nadezhda V.³ (AUTHOR), Tashireva, Liubov A.^1,2 (AUTHOR)

Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 20, p11109. 22p.

B Lymphocytes Are a Predictive Marker of Eribulin Response and Overall Survival in Locally Advanced or Metastatic Breast Cancer: A Multicenter, Two-Cohort, Non-Randomized, Open-Label, Retrospective Study.

Autor: Tashireva, Liubov A., Popova, Nataliya O., Kalinchuk, Anna Yu., Goldberg, Viktor E., Kovalenko, Elena I., Artamonova, Elena V., Manikhas, Aleksey G., Ponomarenko, Dmitriy M., Levchenko, Nataliya V., Rossokha, Elena I., Krasilnikova, Svetlana Yu., Zafirova, Marina A., Choynzonov, Evgeniy L., Perelmuter, Vladimir M.

Publikováno v: Frontiers in Oncology; 6/23/2022, Vol. 12, p1-9, 9p