Zobrazeno 1 - 10
of 48
pro vyhledávání: '"A. Yu. Grishanova"'
Publikováno v:
Сибирский онкологический журнал, Vol 23, Iss 1, Pp 75-86 (2024)
Introduction. Chronic lymphocytic leukemia (CLL) is a disease characterized by large individual differences both in the clinical course and in molecular patterns of expression of genes and regulatory RNAs, which can influence pathological changes. Th
Externí odkaz:
https://doaj.org/article/0281a921990249cebde34dc6833643fe
Publikováno v:
Acta Biomedica Scientifica, Vol 7, Iss 5-2, Pp 31-41 (2022)
CYP2C and CYP3A cytochromes are induced by a variety of compounds and affect the pharmacokinetics and pharmacodynamics of a large number of drugs. Currently, the possibility of using copper coordination compounds in antitumor therapy is being activel
Externí odkaz:
https://doaj.org/article/78edd0ef72634796911f2ca0f16bc179
Publikováno v:
Journal of Ophthalmology, Vol 2014 (2014)
The mitochondria-targeted antioxidant SkQ1 is a novel drug thought to retard development of age-related diseases. It has been shown that SkQ1 reduces clinical signs of retinopathy in senescence-accelerated OXYS rats, which are a known animal model of
Externí odkaz:
https://doaj.org/article/0b941ac4c169468189227e2c50afa1e5
Autor:
Yu. V. Rogushina, I. Yu. Grishanova
Publikováno v:
Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï, Iss 1 (2018)
Пропонується для підвищення релевантності пошуку інформації використовувати знання предметної області пошуку, подані як онтології в і
Externí odkaz:
https://doaj.org/article/de18da35da474636ab96796a79737ecf
Autor:
S. I. Ilnitskaya, V. I. Kapustina, V. I. Kaledin, A. Yu. Grishanova, T. S. Morozkova, L. A. Bogdanova, M. L. Perepechaeva
Publikováno v:
Bulletin of Experimental Biology and Medicine. 162:98-101
The general toxic and hepatocarcinogenic effects of diethylnitrosamine after stimulation of its metabolism with 1,4-bis[2-(3,5-dichloropyridyloxy)]-benzene (TCPOBOP) were studied. The hydroxylating activity of liver microsomes of C57Bl/6Mv mice towar
Autor:
A. Yu. Grishanova, N. V. Baginskaya, V. I. Kaledin, S. I. Ilnitskaya, N. A. Popova, L. A. Bogdanova, M. L. Perepechaeva
Publikováno v:
Biophysics. 59:635-641
The modifying effect of one compound on the carcinogenicity of another in combined application is attributed usually to some changes in the carcinogen metabolism, i.e. its activation or inactivation. In this paper, when used separately, diethylnitros
Autor:
N. P. Domnikova, E. V. Sholenberg, E. V. Mel’nikova, A. Yu. Grishanova, E. A. Gorbachenko, E. V. Vorontsova, T. Yu. Dolgikh, O. B. Goreva
Publikováno v:
Bulletin of Experimental Biology and Medicine. 156:94-97
The levels of CD19 (+) and CD20(+) microvesicles were estimated in the blood of patients with B-cell chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma by flow cytometry method. It was found that the number of B cell microvesicles is seve
Autor:
A. Yu. Grishanova, M. L. Perepechaeva
Publikováno v:
Bulletin of Experimental Biology and Medicine. 154:638-641
Adaptation to cold includes adaptive changes at the organism and molecular levels. One of the interesting facts is induction of cytochromes P450 subfamily 1A (CYP1A) in the liver of rats, inducible enzymes participating in biotransformation of procar
Publikováno v:
Journal of Biophysical Chemistry. :334-340
Cytochrome P4501A (the CYP1A1 and CYP1A2 enzymes) are regulated through the aryl hydrocarbon receptor (AhR)-dependent signal transduction pathway and are generally known as enzymes which metabolize anthropogenic xenobiotics such as dioxin to carcinog
Publikováno v:
Journal of Physiology and Biochemistry. 67:499-510
Cytochrome P4501A (the CYP1A1 and CYP1A2 enzymes) is known to metabolize anthropogenic xenobiotics to carcinogenic and mutagenic compounds. CYP1A1 transcriptional activation is regulated via the aryl hydrocarbon receptor (AhR)-dependent signal transd