Výsledky vyhledávání - "A. Y. Turygin"

Analysis of T-Cell Receptor-γ Gene Rearrangements Using Oligonucleotide Microchip

Autor: Eugene Nikitin, Sergey Surzhikov, Julia V. Sidorova, Tatyana V. Nasedkina, Anait L. Melikyan, Alexander S. Zasedatelev, A. Y. Turygin, Andrey Sudarikov, O. A. Gra

Publikováno v: The Journal of Molecular Diagnostics. 9:249-257

T-cell clonality estimation is important for the differential diagnosis between malignant and nonmalignant T-cell proliferation. Routinely used methods include polymerase chain reaction (PCR) analysis of T-cell receptor-γ (TCR-γ) gene rearrangement

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0df305c8ed34e962f2830f28fe3df61f
https://doi.org/10.2353/jmoldx.2007.060087

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Analysis of Binding Specificity of Disulfide Bonded Dimeric λ-Cro V55C Protein with Generic Hexamer Oligonucleotide Microchip

Autor: M. A. Livshits, E. S. Lomakin, V. R. Chechetkin, O. A. Zasedateleva, Alexander Krylov, A. Y. Turygin, Dmitry Prokopenko, G. I. Gitelson, Lucy Malinina, Mirzabekov Ad

Publikováno v: Journal of Biomolecular Structure and Dynamics. 21:425-433

Binding specificity of mutant V55C disulfide bonded dimeric lambda-Cro protein (CroVC) to double-stranded DNA (dsDNA) was studied using generic hexamer oligonucleotide microchip. The curves of dissociation of hybridized DNA in the presence and absenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eab1d77ff53f7b2b9deafb97cce9087
https://doi.org/10.1080/07391102.2003.10506937

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Kinetics of Hybridization on the Oligonucleotide Microchips with Gel Pads

Autor: N. V. Sorokin, Mirzabekov Ad, A. Y. Turygin, V. A. Vasiliskov, M. A. Livshits, V. R. Chechetkin

Publikováno v: Journal of Biomolecular Structure and Dynamics. 21:279-288

The kinetics of hybridization on the oligonucleotide microchip with gel pads is studied both theoretically and experimentally. The monitoring of kinetics was performed with the measurements of fluorescence intensity produced by the labeled target oli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f874004be3a8600fbd714996e2cca322
https://doi.org/10.1080/07391102.2003.10506923

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Sequencing by Hybridization with the Generic 6-mer Oligonucleotide Microarray: An Advanced Scheme for Data Processing

Autor: Andrei D. Mirzabekov, Dmitry Prokopenko, A. Y. Turygin, V. R. Chechetkin, Eu. V. Kirillov, Dmitri Proudnikov

Publikováno v: Journal of Biomolecular Structure and Dynamics. 18:83-101

DNA sequencing by hybridization was carried out with a microarray of all 4(6) = 4,096 hexadeoxyribonucleotides (the generic microchip). The oligonucleotides immobilized in 100 x 100 x 20-microm polyacrylamide gel pads of the generic microchip were hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b506e6363deb5caceafa562d191b26c
https://doi.org/10.1080/07391102.2000.10506649

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On the spectral criteria of disorder in nonperiodic sequences: application to inflation models, symbolic dynamics and DNA sequences

Autor: V R Chechetkin, A Y Turygin

Publikováno v: Journal of Physics A: Mathematical and General. 27:4875-4898

The spectral representation gives an effective approach to the analysis of statistical characteristics of symbolic sequences. We derive the corresponding criteria for the random case. The criteria ensure the dichotomic classification (random-non-rand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87b3c35f2990b4753706fddc1f48e833
https://doi.org/10.1088/0305-4470/27/14/016

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Gel-based oligonucleotide microarray approach to analyze protein-ssDNA binding specificity

Autor: Elena E. Belobritskaya, Alexander S. Zasedatelev, Alexander V. Chudinov, O. A. Zasedateleva, A. Y. Turygin, V. R. Chechetkin, Dmitry Prokopenko, A. L. Mikheikin

Publikováno v: Nucleic Acids Research

Gel-based oligonucleotide microarray approach was developed for quantitative profiling of binding affinity of a protein to single-stranded DNA (ssDNA). To demonstrate additional capabilities of this method, we analyzed the binding specificity of ribo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84ddeaec61033701613b7873b5b0644
https://pubmed.ncbi.nlm.nih.gov/18474529

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Kinetics of hybridization on surface oligonucleotide microchips: theory, experiment, and comparison with hybridization on gel-based microchips

Autor: M. Y. Donnikov, V. R. Chechetkin, M. A. Livshits, Alexander S. Zasedatelev, O. G. Somova, S. V. Pan'kov, V. E. Barsky, A. Y. Turygin, N. V. Sorokin

Publikováno v: Journal of biomolecular structuredynamics. 24(1)

The optimal design of oligonucleotide microchips and efficient discrimination between perfect and mismatch duplexes strongly depend on the external transport of target DNA to the cells with immobilized probes as well as on respective association and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c512217a4f4955b70506ee6e420640
https://pubmed.ncbi.nlm.nih.gov/16780376

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