Zobrazeno 1 - 10
of 619
pro vyhledávání: '"A. Y. K. Chan"'
Autor:
Liuyang Cai, Hengyan Zhu, Qianqian Mou, Po Yee Wong, Linlin Lan, Cherrie W. K. Ng, Pu Lei, Man Kit Cheung, Daijuanru Wang, Eddy W. Y. Wong, Eric H. L. Lau, Zenon W. C. Yeung, Ronald Lai, Katie Meehan, Sherwood Fung, Kwan Chee A. Chan, Vivian W. Y. Lui, Alfred S. L. Cheng, Jun Yu, Paul K. S. Chan, Jason Y. K. Chan, Zigui Chen
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Dysbiosis of the human oral microbiota has been reported to be associated with oral cavity squamous cell carcinoma (OSCC) while the host-microbiota interactions with respect to the potential impact of pathogenic bacteria on host genomic and
Externí odkaz:
https://doaj.org/article/6d1d6f4104b84fe4850c86de36df8238
Autor:
Alex K. F. Lee, Thomas Hui, Zenon W. C. Yeung, Eddy W. Y. Wong, Jason Y. K. Chan, Eric H. L. Lau
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 9, Iss 3, Pp n/a-n/a (2024)
Abstract Objective We aim to evaluate the safety and effectiveness of radiofrequency ablation (RFA) for benign thyroid nodules by ENT surgeons and to compare it to conventional hemithyroidectomy in the public healthcare, operating theater contained s
Externí odkaz:
https://doaj.org/article/5bf72d71a55949f39a2569b8f4e9c5f5
Autor:
Li Shun Mak, Xiuling Li, Wilson Y. K. Chan, Alex W. K. Leung, Daniel K. L. Cheuk, Liz Y. P. Yuen, Jason C. C. So, Shau Yin Ha, Anthony P. Y. Liu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionMedulloblastoma is the most common malignant brain tumor in children, often requiring intensive multimodal therapy, including chemotherapy with alkylating agents. However, therapy-related complications, such as therapy-related myeloid neo
Externí odkaz:
https://doaj.org/article/63c1abc50de442678a7eb78579556221
Autor:
Mianne Lee, Anna K. Y. Kwong, Martin M. C. Chui, Jeffrey F. T. Chau, Christopher C. Y. Mak, Sandy L. K. Au, Hei Man Lo, Kelvin Y. K. Chan, Vicente A. Yépez, Julien Gagneur, Anita S. Y. Kan, Brian H. Y. Chung
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract RNA sequencing (RNA-seq) is emerging in genetic diagnoses as it provides functional support for the interpretation of variants of uncertain significance. However, the use of amniotic fluid (AF) cells for RNA-seq has not yet been explored. He
Externí odkaz:
https://doaj.org/article/0ab33a9da48e45f390b24d43dc3b0085
Autor:
Man Kit Cheung, Sylvia L. Y. Tong, Martin C. S. Wong, Jason Y. K. Chan, Margaret Ip, Mamie Hui, Christopher K. C. Lai, Rita W. Y. Ng, Wendy C. S. Ho, Apple C. M. Yeung, Paul K. S. Chan, Zigui Chen
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT Recent studies have provided evidence on the presence of an oral–gut microbiota axis in gastrointestinal diseases; however, whether a similar axis exists in healthy individuals is still in debate. Here, we characterized the bacterial and f
Externí odkaz:
https://doaj.org/article/840a681132a4436399f65423fee389c8
Autor:
Christopher K. C. Lai, Man Kit Cheung, Grace C. Y. Lui, Lowell Ling, Jason Y. K. Chan, Rita W. Y. Ng, Hiu Ching Chan, Apple C. M. Yeung, Wendy C. S. Ho, Siaw Shi Boon, Paul K. S. Chan, Zigui Chen
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Numerous studies have reported dysbiosis in the naso- and/or oro-pharyngeal microbiota of COVID-19 patients compared with healthy individuals; however, only a few small-scale studies have also included a disease control group. In this study,
Externí odkaz:
https://doaj.org/article/0a9ec5c470d247b4a19539bc0321a58c
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The genomic characterisation of nasopharyngeal carcinoma (NPC) remains crucial. Here, the authors perform whole-genome sequencing for 70 NPCs with EBV gene expression, report the somatic alterations and EBV-mediated effects converging on NF-κB activ
Externí odkaz:
https://doaj.org/article/84b65b92c11446b886dec64811b68199
Autor:
Zhongqin Gong, Shucai Yang, Minghui Wei, Alexander C. Vlantis, Jason Y. K. Chan, C. Andrew van Hasselt, Dongcai Li, Xianhai Zeng, Lingbin Xue, Michael C. F. Tong, George G. Chen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The incidence of thyroid cancer was predominant in women, indicating that the sex hormone may have a role in thyroid cancer development. Generally, the sex hormone exerts its function by binding to the correspondent nuclear receptors. Therefore, aber
Externí odkaz:
https://doaj.org/article/5bdcecf656f142669a720827f210e1d1
Autor:
Katherine W. K. Lai, Ronald Lai, Balazs B. Lorincz, Chen-Chi Wang, Jason Y. K. Chan, David C. M. Yeung
Publikováno v:
Frontiers in Surgery, Vol 8 (2022)
ObjectivesHypopharyngeal carcinoma (HPC) is a head and neck carcinoma with poor prognosis. Traditional laryngopharyngectomy offered promising oncological outcomes at the cost of functional outcomes. The recent advent in transoral robotic surgery (TOR
Externí odkaz:
https://doaj.org/article/a29b631f76be42e5a92c450b7133d370
Autor:
Xiang Shu, Jirong Long, Qiuyin Cai, Sun-Seog Kweon, Ji-Yeob Choi, Michiaki Kubo, Sue K. Park, Manjeet K. Bolla, Joe Dennis, Qin Wang, Yaohua Yang, Jiajun Shi, Xingyi Guo, Bingshan Li, Ran Tao, Kristan J. Aronson, Kelvin Y. K. Chan, Tsun L. Chan, Yu-Tang Gao, Mikael Hartman, Weang Kee Ho, Hidemi Ito, Motoki Iwasaki, Hiroji Iwata, Esther M. John, Yoshio Kasuga, Ui Soon Khoo, Mi-Kyung Kim, Sun-Young Kong, Allison W. Kurian, Ava Kwong, Eun-Sook Lee, Jingmei Li, Artitaya Lophatananon, Siew-Kee Low, Shivaani Mariapun, Koichi Matsuda, Keitaro Matsuo, Kenneth Muir, Dong-Young Noh, Boyoung Park, Min-Ho Park, Chen-Yang Shen, Min-Ho Shin, John J. Spinelli, Atsushi Takahashi, Chiuchen Tseng, Shoichiro Tsugane, Anna H. Wu, Yong-Bing Xiang, Taiki Yamaji, Ying Zheng, Roger L. Milne, Alison M. Dunning, Paul D. P. Pharoah, Montserrat García-Closas, Soo-Hwang Teo, Xiao-ou Shu, Daehee Kang, Douglas F. Easton, Jacques Simard, Wei Zheng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
In breast cancer, genome-wide associations studies (GWAS) have highlighted loci associated with disease risk. Here, the authors perform a meta-analysis of GWAS data from Asian populations, discovering 31 potential new risk loci, 10 of which are valid
Externí odkaz:
https://doaj.org/article/532b4d0876ab46de877da9effc1e588e