Zobrazeno 1 - 10
of 1 019
pro vyhledávání: '"A. Weikl"'
Autor:
Bonazzi, Francesco, Weikl, Thomas R.
Besides direct molecular interactions, proteins and nanoparticles embedded in or adsorbed to membranes experience indirect interactions that are mediated by the membranes. These membrane-mediated interactions arise from the membrane curvature induced
Externí odkaz:
http://arxiv.org/abs/2407.04027
Membrane-induced interactions have been predicted to be important for the organization of membrane proteins. Measurements of the interactions between two and three membrane deforming objects have revealed their non-additive nature. They are thought t
Externí odkaz:
http://arxiv.org/abs/2403.05253
Autor:
Raluca Groza, Kita Valerie Schmidt, Paul Markus Müller, Paolo Ronchi, Claire Schlack-Leigers, Ursula Neu, Dmytro Puchkov, Rumiana Dimova, Claudia Matthaeus, Justin Taraska, Thomas R. Weikl, Helge Ewers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Several bacterial toxins and viruses can deform membranes through multivalent binding to lipids for clathrin-independent endocytosis. However, it remains unclear, how membrane deformation and endocytic internalization are mechanistically lin
Externí odkaz:
https://doaj.org/article/232cba3680a14426a2a571dded62d071
Autor:
Kazem Asadollahi, Sunnia Rajput, Lazarus Andrew de Zhang, Ching-Seng Ang, Shuai Nie, Nicholas A. Williamson, Michael D. W. Griffin, Ross A. D. Bathgate, Daniel J. Scott, Thomas R. Weikl, Guy N. L. Jameson, Paul R. Gooley
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The conformational ensembles of G protein-coupled receptors (GPCRs) include inactive and active states. Spectroscopy techniques, including NMR, show that agonists, antagonists and other ligands shift the ensemble toward specific states depen
Externí odkaz:
https://doaj.org/article/8a32b17098464f42af0a3f2a34e66fbb
Autor:
Anna-Jasmina Donaubauer, Ina Becker, Gerhart Klein, Reinhard E. Voll, Lena Weikl, Martin Klieser, Shakar Barzangi, Jian-Guo Zhou, Rainer Fietkau, Udo S. Gaipl, Benjamin Frey
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
In this randomized, placebo-controlled cross-over trial we aimed to investigate if radon spa therapy exerts more pain relief than exposure to warm water alone. In addition, immunological parameters were assessed in both treatment groups. In the RAD-O
Externí odkaz:
https://doaj.org/article/7d616c35ad4c42ac9f06c39b70256dd8
Publikováno v:
Nanoscale, 2020, DOI: 10.1039/D0NR03696J
Carbohydrates such as the trisaccharide motif LeX are key constituents of cell surfaces. Despite intense research, the interactions between carbohydrates of apposing cells or membranes are not well understood. In this article, we investigate carbohyd
Externí odkaz:
http://arxiv.org/abs/2008.01470
Biological membranes are shaped by various proteins that either generate inward or outward membrane curvature. In this article, we investigate the membrane morphologies induced by mixtures of arc-shaped particles with coarse-grained modeling and simu
Externí odkaz:
http://arxiv.org/abs/2004.00987
Autor:
Weikl, Markus, Peschel, Andreas
Publikováno v:
In Current Opinion in Green and Sustainable Chemistry December 2023 44
The adhesion of biomembranes is mediated by the binding of membrane-anchored receptor and ligand proteins. The proteins can only bind if the separation between apposing membranes is sufficiently close to the length of the protein complexes, which lea
Externí odkaz:
http://arxiv.org/abs/1911.09352
Autor:
Bonazzi, Francesco, Weikl, Thomas R.
The intricate shapes of biological membranes such as tubules and membrane stacks are induced by proteins. In this article, we systematically investigate the membrane shapes induced by arc-shaped scaffolds such as proteins and protein complexes with c
Externí odkaz:
http://arxiv.org/abs/1902.08470