Zobrazeno 1 - 10 of 170 pro vyhledávání: '"A. W. WOUTERS"'
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Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma
Autor: Irene L. M. Reijers, Alexander M. Menzies, Alexander C. J. van Akkooi, Judith M. Versluis, Noëlle M. J. van den Heuvel, Robyn P. M. Saw, Thomas E. Pennington, Ellen Kapiteijn, Astrid A. M. van der Veldt, Karijn P. M. Suijkerbuijk, Geke A. P. Hospers, Elisa A. Rozeman, Willem M. C. Klop, Winan J. van Houdt, Karolina Sikorska, Jos A. van der Hage, Dirk J. Grünhagen, Michel W. Wouters, Arjen J. Witkamp, Charlotte L. Zuur, Judith M. Lijnsvelt, Alejandro Torres Acosta, Lindsay G. Grijpink-Ongering, Maria Gonzalez, Katarzyna Jóźwiak, Carolien Bierman, Kerwin F. Shannon, Sydney Ch’ng, Andrew J. Colebatch, Andrew J. Spillane, John B. A. G. Haanen, Robert V. Rawson, Bart A. van de Wiel, Lonneke V. van de Poll-Franse, Richard A. Scolyer, Annelies H. Boekhout, Georgina V. Long, Christian U. Blank
Publikováno v: Nature Medicine, 28(6), 1178-+. NATURE PORTFOLIO
Nature Medicine, 28(6), 1178-1188. Nature Publishing Group
Nature Medicine
Nature medicine, 28(6), 1178-1188. Nature Publishing Group
Nature Medicine, 28. Nature Publishing Group
Neoadjuvant ipilimumab and nivolumab induces high pathologic response rates (pRRs) in clinical stage III nodal melanoma, and pathologic response is strongly associated with prolonged relapse-free survival (RFS). The PRADO extension cohort of the OpAC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d79d3cfe1f3c168f561afa30efdc6c
https://doi.org/10.1038/s41591-022-01851-x
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IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma
Autor: Irene L.M. Reijers, Disha Rao, Judith M. Versluis, Alexander M. Menzies, Petros Dimitriadis, Michel W. Wouters, Andrew J. Spillane, Willem M.C. Klop, Annegien Broeks, Linda J.W. Bosch, Marta Lopez-Yurda, Winan J. van Houdt, Robert V. Rawson, Lindsay G. Grijpink-Ongering, Maria Gonzalez, Sten Cornelissen, Jasper Bouwman, Joyce Sanders, Elsemieke Plasmeijer, Yannick S. Elshot, Richard A. Scolyer, Bart A. van de Wiel, Daniel S. Peeper, Alexander C.J. van Akkooi, Georgina V. Long, Christian U. Blank
Publikováno v: Reijers, I L M, Rao, D, Versluis, J M, Menzies, A M, Dimitriadis, P, Wouters, M W, Spillane, A J, Klop, W M C, Broeks, A, Bosch, L J W, Lopez-Yurda, M, van Houdt, W J, Rawson, R V, Grijpink-Ongering, L G, Gonzalez, M, Cornelissen, S, Bouwman, J, Sanders, J, Plasmeijer, E, Elshot, Y S, Scolyer, R A, van de Wiel, B A, Peeper, D S, van Akkooi, A C J, Long, G V & Blank, C U 2023, ' IFN-γ signature enables selection of neoadjuvant treatment in patients with stage III melanoma ', Journal of Experimental Medicine, vol. 220, no. 5, e20221952 . https://doi.org/10.1084/jem.20221952
Journal of experimental medicine, 220(5):e20221952. Rockefeller University Press
Journal of Experimental Medicine, 220(5):e20221952. Rockefeller University Press
Neoadjuvant ipilimumab + nivolumab has demonstrated high pathologic response rates in stage III melanoma. Patients with low intra-tumoral interferon-γ (IFN-γ) signatures are less likely to benefit. We show that domatinostat (a class I histone deace
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17999c5aac89a5332bee79a05cb4e596
https://doi.org/10.1084/jem.20221952
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4
Akademický článek
What drives centralisation in cancer care?
Autor: Melvin J Kilsdonk, Sabine Siesling, Boukje A C van Dijk, Michel W Wouters, Wim H van Harten
Publikováno v: PLoS ONE, Vol 13, Iss 4, p e0195673 (2018)
To improve quality of care, centralisation of cancer services in high-volume centres has been stimulated. Studies linking specialisation and high (surgical) volumes to better outcomes already appeared in the 1990's. However, actual centralisation was
Externí odkaz: https://doaj.org/article/2fe3ef663b05486796c2001add0b361a
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5
Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanoma
Autor: Irene L. M. Reijers, Robert V. Rawson, Andrew J. Colebatch, Elisa A. Rozeman, Alex M. Menzies, Alexander C. J. van Akkooi, Kerwin F. Shannon, Michel W. Wouters, Robyn P. M. Saw, Winan J. van Houdt, Charlotte L. Zuur, Omgo E. Nieweg, Sydney Ch’ng, W. Martin C. Klop, Andrew J. Spillane, Georgina V. Long, Richard A. Scolyer, Bart A. van de Wiel, Christian U. Blank
Publikováno v: JAMA Surgery, 157(4), 335-342. AMER MEDICAL ASSOC
JAMA surgery, 157(4), 335-342. American Medical Association
Importance: Neoadjuvant checkpoint inhibition in patients with high-risk stage III melanoma shows high pathologic response rates associated with a durable relapse-free survival. Whether a therapeutic lymph node dissection (TLND) can be safely omitted
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83255a1603596ffca3ab7f4e60dc4be4
https://doi.org/10.1001/jamasurg.2021.7554
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6
Variation in head and neck cancer care in the Netherlands: A retrospective cohort evaluation of incidence, treatment and outcome
Autor: M, de Ridder, A J M, Balm, R J, Baatenburg de Jong, C H J, Terhaard, R P, Takes, M, Slingerland, E, Dik, R J E, Sedee, J G A M, de Visscher, H, Bouman, S M, Willems, M W, Wouters, L E, Smeele, B A C, van Dijk
Publikováno v: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 43(8)
To explore variation in numbers and treatment between hospitals that treat head and neck cancer (HNC) in the Netherlands.Patient, tumor and treatment characteristics were collected from the Netherlands Cancer Registry, while histopathological feature
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6e69a9ab7c1360c3a7756cfba642fc69
https://pubmed.ncbi.nlm.nih.gov/28336186
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7
Angiotensin II Type 1 Receptor Blockade Does Not Enhance Apoptotic Cell Death During Ischemia and Reperfusion in Humans In Vivo
Autor: Otto C. Boerman, Gert Jan Scheffer, Paul Smits, Gerard A. Rongen, Constantijn W. Wouters, Wim J.G. Oyen, P. Meijer
Publikováno v: Journal of Cardiovascular Pharmacology, 57, 702-6
Journal of Cardiovascular Pharmacology, 57, 6, pp. 702-6
Contains fulltext : 96636.pdf (Publisher’s version ) (Closed access) Despite the theoretical benefits, angiotensin II type 1 receptor antagonists seem to enhance rather than reduce morbidity and mortality after myocardial infarction compared with a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bd619fdc300189c301647c0fc309e8
https://doi.org/10.1097/fjc.0b013e318218ef21
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8
Upregulation of Ecto-5′-Nucleotidase by Rosuvastatin Increases the Vasodilator Response to Ischemia
Autor: Gert Jan Scheffer, Gerard A. Rongen, Petra H.H. van den Broek, Paul Smits, Maarten de Rooij, Constantijn W. Wouters, P. Meijer
Publikováno v: Hypertension, 56, 4, pp. 722-7
Hypertension, 56, 722-7
Contains fulltext : 87537.pdf (Publisher’s version ) (Open Access) 3-Hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors (statins) are effective in the primary and secondary prevention of cardiovascular events. Although originally developed t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d3aa4c3b5657fca6ed52589915c024
https://doi.org/10.1161/hypertensionaha.110.155689
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9
Endotoxin tolerance does not limit mild ischemia-reperfusion injury in humans in vivo
Autor: Niels P. Riksen, Otto C. Boerman, Annelies Draisma, Johannes G. van der Hoeven, Peter Pickkers, Wim J.G. Oyen, Constantijn W. Wouters, M. van Deuren, Moniek de Goeij, Gerard A. Rongen
Publikováno v: Innate Immunity, 15, 6, pp. 360-7
Innate Immunity, 15, 360-7
Contains fulltext : 80768.pdf (Publisher’s version ) (Closed access) Animal studies have shown that previous exposure to lipopolysaccharide (LPS) can limit ischemia-reperfusion injury. We tested whether pretreatment with LPS also protects against i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4f60961cfed11f936226eb1aa6ec27
https://doi.org/10.1177/1753425909105548
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10
Dipyridamole enhances ischaemia-induced reactive hyperaemia by increased adenosine receptor stimulation
Autor: P.L.C. van den Broek, Gerard A. Rongen, Niels P. Riksen, Gert Jan Scheffer, Paul Smits, Constantijn W. Wouters, P. Meijer
Publikováno v: British Journal of Pharmacology. 153:1169-1176
Background and purpose: Dipyridamole enhances post-occlusive reactive hyperaemia (PORH) in the human forearm vascular bed. We hypothesize that this effect is completely mediated by increased adenosine receptor stimulation. To test this hypothesis, th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::518374f0b570afb2b496eb9243616f19
https://doi.org/10.1038/bjp.2008.10
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