Zobrazeno 1 - 10
of 1 933
pro vyhledávání: '"A. W. Schmid"'
Autor:
Harim I. Won, Samuel Zinga, Olga Kandror, Tatos Akopian, Ian D. Wolf, Jessica T. P. Schweber, Ernst W. Schmid, Michael C. Chao, Maya Waldor, Eric J. Rubin, Junhao Zhu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Proteolysis-targeting chimeras (PROTACs) represent a new therapeutic modality involving selectively directing disease-causing proteins for degradation through proteolytic systems. Our ability to exploit targeted protein degradation (TPD) for
Externí odkaz:
https://doaj.org/article/b9ac70b36b4b4800bd5cfffe2f4e65d9
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Cell-surface receptors play pivotal roles in many biological processes, including immunity, development, and reproduction, across diverse organisms. How cell-surface receptors evolve to become specialised in different biological processes re
Externí odkaz:
https://doaj.org/article/7ee44b2afe7f46ca978802cd509e0042
Publikováno v:
Ecology and Evolution, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Duckweeds, including the common duckweed Lemna minor, are increasingly used to test eco‐evolutionary theories. Yet, despite its popularity and near‐global distribution, the understanding of its population structure (and genetic variation
Externí odkaz:
https://doaj.org/article/211814f80ebc4c0595a98d0c7a6caefa
Autor:
Kyle Hartman, Marc W. Schmid, Natacha Bodenhausen, S. Franz Bender, Alain Y. Valzano-Held, Klaus Schlaeppi, Marcel G.A. van der Heijden
Publikováno v:
Environmental Microbiome, Vol 18, Iss 1, Pp 1-16 (2023)
Abstract Background A major aim in plant microbiome research is determining the drivers of plant-associated microbial communities. While soil characteristics and host plant identity present key drivers of root microbiome composition, it is still unre
Externí odkaz:
https://doaj.org/article/e03df8945dcc4d3fa4f1d27b9c214230
Autor:
Maëva Labouyrie, Cristiano Ballabio, Ferran Romero, Panos Panagos, Arwyn Jones, Marc W. Schmid, Vladimir Mikryukov, Olesya Dulya, Leho Tedersoo, Mohammad Bahram, Emanuele Lugato, Marcel G. A. van der Heijden, Alberto Orgiazzi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Factors driving microbial community composition and diversity are well established but the relationship with microbial functioning is poorly understood, especially at large scales. We analysed microbial biodiversity metrics and distribution
Externí odkaz:
https://doaj.org/article/9d277923ae524976898ebeaa93d464a7
Autor:
K. Greimelmaier, N. Klopp, E. Mairinger, M. Wessolly, S. Borchert, J. Steinborn, K. W. Schmid, J. Wohlschlaeger, F. D. Mairinger
Publikováno v:
Pathology and Oncology Research, Vol 29 (2023)
Background: Colorectal cancer (CRC) is still one of the leading causes of cancer death worldwide, emphasizing the need for further diagnostic and therapeutic approaches. Cancer invasion and metastasis are affected by the tumor microenvironment (TME),
Externí odkaz:
https://doaj.org/article/989897ef0ade43aeb714a8883787ea72
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112986- (2023)
Summary: Pancreatic β cells display functional and transcriptional heterogeneity in health and disease. The sequence of events leading to β cell heterogeneity during metabolic stress is poorly understood. Here, we characterize β cell responses to
Externí odkaz:
https://doaj.org/article/3b4bbb1407e641dbbe3ce31495d7be14
Autor:
Dominik W. Schmid, Gloria Fackelmann, Wasimuddin, Jacques Rakotondranary, Yedidya R. Ratovonamana, B. Karina Montero, Jörg U. Ganzhorn, Simone Sommer
Publikováno v:
Animal Microbiome, Vol 4, Iss 1, Pp 1-15 (2022)
Abstract Parasitic infections disturb gut microbial communities beyond their natural range of variation, possibly leading to dysbiosis. Yet it remains underappreciated that most infections are accompanied by one or more co-infections and their collec
Externí odkaz:
https://doaj.org/article/f5b776aea8ae4b4cb9af03c5aa213d18
Autor:
M. Teresa Boquete, Marc W. Schmid, Niels C.A.M. Wagemaker, Sarah B. Carey, Stuart F. McDaniel, Christina L. Richards, Conchita Alonso
Publikováno v:
Data in Brief, Vol 45, Iss , Pp 108710- (2022)
Studying how different plant groups deal with heavy metal exposure is crucial to improve our understanding of the diversity of molecular mechanisms involved in plant stress response. Here, we used RNA sequencing (RNA-seq) and epigenotyping by sequenc
Externí odkaz:
https://doaj.org/article/ff1c6d058151451eb7e4ada8a3c8b650
Autor:
Chandra Ramakrishnan, Aarti Krishnan, Samuel Francisco, Marc W Schmid, Giancarlo Russo, Alexandre Leitão, Andrew Hemphill, Dominique Soldati-Favre, Adrian B Hehl
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010955 (2022)
Cyst-forming Apicomplexa (CFA) of the Sarcocystidae have a ubiquitous presence as pathogens of humans and farm animals transmitted through the food chain between hosts with few notable exceptions. The defining hallmark of this family of obligate intr
Externí odkaz:
https://doaj.org/article/32c60b09b50947dda74d5e00dc308b11