Zobrazeno 1 - 10
of 966
pro vyhledávání: '"A. W. Norris"'
Autor:
Pavana G. Rotti, Yaling Yi, Grace Gasser, Feng Yuan, Xingshen Sun, Idil Apak-Evans, Peipei Wu, Guangming Liu, Soon Choi, Rosie Reeves, Attilina E. Scioneaux, Yulong Zhang, Michael Winter, Bo Liang, Nathan Cunicelli, Aliye Uc, Andrew W. Norris, Lori Sussel, Kristen L. Wells, John F. Engelhardt
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111393- (2024)
Summary: Inflammation, acinar atrophy, and ductal hyperplasia drive pancreatic remodeling in newborn cystic fibrosis (CF) ferrets lacking a functional cystic fibrosis conductance regulator (CFTR) channel. These changes are associated with a transient
Externí odkaz:
https://doaj.org/article/adf31ce97f1349c6913af02b6606f692
Autor:
Mark Ziemann, Mandhri Abeysooriya, Anusuiya Bora, Séverine Lamon, Mary Sravya Kasu, Mitchell W. Norris, Yen Ting Wong, Jeffrey M. Craig
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
Infinium Methylation BeadChip arrays remain one of the most popular platforms for epigenome-wide association studies, but tools for downstream pathway analysis have their limitations. Functional class scoring (FCS) is a group of pathway enrichment te
Externí odkaz:
https://doaj.org/article/d2542601d7ed49bda4a91de1d496cb20
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
IntroductionWidely used measures of self-reported subjective well-being and flourishing generally do not directly measure positive experiences that have been demonstrated to improve subjective well-being and flourishing, which could aid in developing
Externí odkaz:
https://doaj.org/article/5cf4d73de5a341dd9e89234946ebaa43
Autor:
Olivia Williamson, Valery Varela, Christopher Minami, Juliana Tom, Elizabeth Powell, Jeffrey W. Norris
Publikováno v:
Veterinary Evidence, Vol 9, Iss 2 (2024)
The original article was published in Veterinary Evidence Vol 9, Issue 1 (2024): https://doi.org/10.18849/ve.v9i1.679 In the original version of the article the contributions of one of the authors, Christopher Minami, were listed as "Investigation,
Externí odkaz:
https://doaj.org/article/4cdf0e9a15fd44e28a8018fbf8e265f0
Autor:
Qiuxia Li, Quanjiang Zhang, Young-Rae Kim, Ravinder Reddy Gaddam, Julia S. Jacobs, Markus M. Bachschmid, Tsneem Younis, Zhiyong Zhu, Leonid Zingman, Barry London, Adam J. Rauckhorst, Eric B. Taylor, Andrew W. Norris, Ajit Vikram, Kaikobad Irani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Downregulation of endothelial Sirtuin1 (Sirt1) in insulin resistant states contributes to vascular dysfunction. Furthermore, Sirt1 deficiency in skeletal myocytes promotes insulin resistance. Here, we show that deletion of endothelial Sirt1,
Externí odkaz:
https://doaj.org/article/72b47199e1ba4328a43cb9d21627ccbf
Autor:
Olivia Williamson, Valery Varela, Christopher Minami, Juliana Tom, Elizabeth Powell, Jeffrey W. Norris
Publikováno v:
Veterinary Evidence, Vol 9, Iss 1 (2024)
PICO Question In dogs with anxious behaviours, is fluoxetine more effective than clomipramine in reducing anxiety-related behaviours? Clinical bottom line Category of research Treatment. Number and type of study designs reviewed Three co
Externí odkaz:
https://doaj.org/article/01269a3a827a4d6bb929cba2dd4acbc3
Autor:
Susheel K. Gunasekar, Litao Xie, Ashutosh Kumar, Juan Hong, Pratik R. Chheda, Chen Kang, David M. Kern, Chau My-Ta, Joshua Maurer, John Heebink, Eva E. Gerber, Wojciech J. Grzesik, Macaulay Elliot-Hudson, Yanhui Zhang, Phillip Key, Chaitanya A. Kulkarni, Joseph W. Beals, Gordon I. Smith, Isaac Samuel, Jessica K. Smith, Peter Nau, Yumi Imai, Ryan D. Sheldon, Eric B. Taylor, Daniel J. Lerner, Andrew W. Norris, Samuel Klein, Stephen G. Brohawn, Robert Kerns, Rajan Sah
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-25 (2022)
Type 2 diabetes is associated with insulin resistance, impaired insulin secretion and liver steatosis. Here the authors report a proof-of-concept study for small molecule SWELL1 modulators as a therapeutic approach to treat diabetes and associated li
Externí odkaz:
https://doaj.org/article/f4d1fee19c624c0a9f1b40ef56f78e04
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Turner syndrome (TS) is a common chromosomal disorder resulting from complete or partial absence of the second sex chromosome. Hyperglycemia, ranging from impaired glucose tolerance (IGT) to diabetes mellitus (DM), is common in TS. DM in individuals
Externí odkaz:
https://doaj.org/article/466c3742da354410be72a32c82bac0cb
Autor:
Christine L. Chan, Andrea Granados, Amir Moheet, Sachinkumar Singh, Timothy Vigers, Ana Maria Arbeláez, Yaling Yi, Shanming Hu, Andrew W. Norris, Katie Larson Ode
Publikováno v:
Journal of Clinical & Translational Endocrinology, Vol 30, Iss , Pp 100311- (2022)
Background: Diabetes is prevalent among people with CF (PwCF) and associated with worse clinical outcomes. CFTR modulators are highly effective in improving the disease course of CF. However, the effects of elexacaftor/tezacaftor/ivacaftor (ETI) on g
Externí odkaz:
https://doaj.org/article/316d9cb57ebf475b8bd56a5deb9465d7
Autor:
Ryan C Vignogna, Mariateresa Allocca, Maria Monticelli, Joy W Norris, Richard Steet, Ethan O Perlstein, Giuseppina Andreotti, Gregory I Lang
Publikováno v:
eLife, Vol 11 (2022)
The most common cause of human congenital disorders of glycosylation (CDG) are mutations in the phosphomannomutase gene PMM2, which affect protein N-linked glycosylation. The yeast gene SEC53 encodes a homolog of human PMM2. We evolved 384 population
Externí odkaz:
https://doaj.org/article/12fb21d1e1c5435787fcfc54b0ca4d30