Zobrazeno 1 - 10
of 247
pro vyhledávání: '"A. W. Lipkowski"'
Autor:
Kaja Kasarełło, Agnieszka Szczepankowska, Barbara Kwiatkowska-Patzer, Andrzej W. Lipkowski, Roman Gadamski, Dorota Sulejczak, Magdalena Łachwa, Michał Biały, Jacek Bardowski
Publikováno v:
Folia Neuropathologica, Vol 54, Iss 3, Pp 249-258 (2016)
Multiple sclerosis (MS) is a human autoimmune neurodegenerative disease with an unknown etiology. Despite various therapies, there is no effective cure for MS. Since the mechanism of the disease is based on autoreactive T-cell responses directed agai
Externí odkaz:
https://doaj.org/article/f1f076b227a34fccbe8d161c670068cb
Autor:
Marta Sowinska, Maja Morawiak, Marta Bochyńska-Czyż, Andrzej W. Lipkowski, Elżbieta Ziemińska, Barbara Zabłocka, Zofia Urbanczyk-Lipkowska
Publikováno v:
Biomolecules, Vol 9, Iss 3, p 89 (2019)
Background: Exposure to ozone level and ultraviolet (UV) radiation is one of the major concerns in the context of public health. Numerous studies confirmed that abundant free radicals initiate undesired processes, e.g. carcinogenesis, cells degenerat
Externí odkaz:
https://doaj.org/article/986f4cc0a67447119ae4d2df7c1638d4
Publikováno v:
ARKIVOC, Vol 2012, Iss 5, Pp 163-174 (2012)
Externí odkaz:
https://doaj.org/article/b50be569aed3472d872793b8954689d2
Autor:
Sergiusz Markowicz, Joanna Matalinska, Katarzyna Kurzepa, Marta Bochynska, Marzena Biernacka, Anna Samluk, Dorota Dudek, Henryk Skurzak, Masaaki Yoshikawa, Andrzej W Lipkowski
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98073 (2014)
The primary function of hair and fur covering mammalian skin is to provide mechanical and thermal protection for the body. The proteins that constitute hair are extremely resistant to degradation by environmental factors. However, even durable materi
Externí odkaz:
https://doaj.org/article/ae38e2aa526c416bb14dab47a051200d
Autor:
Marta Bochyńska-Czyż, Anna Laskowska, Adam Guśpiel, Zofia Urbanczyk-Lipkowska, Jolanta Solecka, Andrzej W. Lipkowski, Marta Sowinska, Katarzyna Trzeciak
Publikováno v:
Bioconjugate Chemistry. 29:3571-3585
Evolution-derived natural compounds have been inspirational for design of numerous pharmaceuticals, e.g., penicillins and tetracyclines. Herein, we present a bioinspired strategy to design peptide dendrimers for the effective therapy of E. coli infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe3d0a59c90a0bcafc4bdb0fe5307288
https://doi.org/10.1021/acs.bioconjchem.8b00544
https://doi.org/10.1021/acs.bioconjchem.8b00544
Publikováno v:
European Journal of Pharmacology. 810:9-14
AWL3106 composed of opioid (dermorphin) and tachykinin (substance P7-11) pharmacophores is a new compound with high analgesic potency and markedly reduced ability to induce tolerance and dependence. The present study aimed to determine the respirator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce8bf20e33cb8a4d6bdd910136fbc55
https://doi.org/10.1016/j.ejphar.2017.06.012
https://doi.org/10.1016/j.ejphar.2017.06.012
Autor:
Piotr Wojciechowski, Monika Jampolska, Patrycja Kleczkowska, Katarzyna Kaczyńska, Andrzej W. Lipkowski
Publikováno v:
European Journal of Pharmacology. 797:20-25
Aim Chimeric compound – PK20 despite its therapeutic activity on nociceptive and inflammatory processes may affect respiration and blood pressure. Our objective was to evaluate influence of the hybrid composed of endomorphin-2 and neurotensin fragm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2709f27c070367a41f74aac708ac945
https://doi.org/10.1016/j.ejphar.2017.01.010
https://doi.org/10.1016/j.ejphar.2017.01.010
Autor:
Aandrzej W. Lipkowski, Dorota Sulejczak, Aleksandra Misicka, Joanna Czuwara, Marek Konop, Piotr Kosson, Lidia Rudnicka
Publikováno v:
Wound Repair and Regeneration. 25:62-74
Keratin is an interesting protein needed for wound healing and tissue recovery. We have recently proposed a new, simple and inexpensive method to obtain fur and hair keratin-derived biomaterials suitable for medical application. The aim of the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::398b6ea5ce98c24664d50546a275e780
https://doi.org/10.1111/wrr.12500
https://doi.org/10.1111/wrr.12500
Autor:
Marta Bochyńska-Czyż, Steven Ballet, Piotr F. J. Lipiński, Anna Leśniak, Aleksandra Misicka, Piotr Kosson, Jolanta Dyniewicz, Dirk Tourwé, Andrzej W. Lipkowski, Adriana Muchowska
Publikováno v:
ACS Medicinal Chemistry Letters. 8:73-77
The area of multitarget compounds, joining two pharmacophores within one molecule, is a vivid field of research in medicinal chemistry. Not only pharmacophoric elements are essential for the design and activity of such compounds, but the type and len
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a2562a0ac6082067812255a406af5a7
https://doi.org/10.1021/acsmedchemlett.6b00381
https://doi.org/10.1021/acsmedchemlett.6b00381
Publikováno v:
Respiratory Physiology & Neurobiology. 233:7-13
Experiments were performed in anaesthetized, spontaneously breathing rats to: (1) analyse the respiratory and cardiovascular effects of C-terminal fragment of substance P (AWL2077) as referred to those exerted by the parent undecapeptide, (2) determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7017406053537c65b139d8b05ba040c
https://doi.org/10.1016/j.resp.2016.07.006
https://doi.org/10.1016/j.resp.2016.07.006