Zobrazeno 1 - 10
of 196
pro vyhledávání: '"A. Vijaya Mohan Rao"'
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Crohn’s disease and ulcerative colitis are the two forms of disorders of the human inflammatory bowel disease with unknown etiologies. Endothelial cell protein C receptor (EPCR) is a multifunctional and multiligand receptor, which is expre
Externí odkaz:
https://doaj.org/article/85c508b614b942408bc8046a59867658
Autor:
Kaushik Das, L. Vijaya Mohan Rao
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15479 (2022)
Inflammation is a biological response of the immune system to various insults, such as pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro- and anti-inflammatory factors and their direction towards inflammation often
Externí odkaz:
https://doaj.org/article/586bf325ac3d4900ab0a2a0873f5a36d
Publikováno v:
Blood Advances, Vol 1, Iss 25, Pp 2399-2413 (2017)
Abstract: Many pathophysiologic agents transform cryptic tissue factor (TF) on cells to prothrombotic TF, and one such stimulus is 4-hydroxy-2-nonenal (HNE), the most abundant aldehyde produced by the oxidation of ω-6 polyunsaturated fatty acids. HN
Externí odkaz:
https://doaj.org/article/27b055a35a3246809b0724192dbb2698
Autor:
Vijay Kondreddy, Shiva Keshava, Kaushik Das, Jhansi Magisetty, L. Vijaya Mohan Rao, Usha R. Pendurthi
Publikováno v:
Blood. 140:1549-1564
Deep vein thrombosis (DVT) is the third most common cause of cardiovascular mortality. Several studies suggest that DVT occurs at the intersection of dysregulated inflammation and coagulation upon activation of inflammasome and secretion of interleuk
Autor:
Shiva Keshava, Jagan Sundaram, Anuradha Rajulapati, Charles T. Esmon, Usha R. Pendurthi, L. Vijaya Mohan Rao
Publikováno v:
Blood Advances, Vol 1, Iss 15, Pp 1206-1214 (2017)
Abstract: Recent studies established that clotting factor VIIa (FVIIa) binds endothelial cell protein C receptor (EPCR). It has been speculated that FVIIa interaction with EPCR might augment the hemostatic effect of recombinant FVIIa (rFVIIa) in ther
Externí odkaz:
https://doaj.org/article/414c43275e3f4e399e2a807b14913bcc
Publikováno v:
Blood Advances, Vol 1, Iss 13, Pp 849-862 (2017)
Abstract: A majority of tissue factor (TF) on cell surfaces exists in an encrypted state with minimal to no procoagulant activity. At present, it is unclear whether limited availability of phosphatidylserine (PS) and/or a specific membrane lipid in t
Externí odkaz:
https://doaj.org/article/3bce09633bc04ba798de34219ccd000b
Autor:
Usha R. Pendurthi, L. Vijaya Mohan Rao, Steven Idell, Torry A. Tucker, Sanghamitra Sahoo, Shiva Keshava
The procoagulant protein tissue factor (F3) is a powerful growth promoter in many tumors, but its mechanism of action is not well understood. More generally, it is unknown whether hemostatic factors expressed on tumor cells influence tissue factor-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::254e9d0b4af1fc3d0e2e2f0d485d4388
https://doi.org/10.1158/0008-5472.c.6504674
https://doi.org/10.1158/0008-5472.c.6504674
Autor:
Usha R. Pendurthi, L. Vijaya Mohan Rao, Steven Idell, Torry A. Tucker, Sanghamitra Sahoo, Shiva Keshava
Supplementary File PDF 277K, Supplementary Methods: Includes additional details of reagents and methodology, and references. Supplementary Figure 1: Effect of FVIIa and thrombin on cell proliferation of wild-type REN, TF- or PAR1- knocked-down REN MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cb6172e32bab062ce05115f6568b43
https://doi.org/10.1158/0008-5472.22396844.v1
https://doi.org/10.1158/0008-5472.22396844.v1
Pyoderma gangrenosum, Acne, and Hidradenitis Suppurativa (PASH) is a rare inflammatory syndrome, the exact etiology and pathogenesis of which remains unknown. PASH syndrome belongs to the spectrum of Interleukin-1 driven auto-inflammatory diseases.In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ea6dc879435ad999ebf3fe0d822616
Erythokeratodermavariabilis(EKV) is rareAutosomal dominantdisease with two types of presentations.Onset is usuallyininfancy.Twotypesoflesions: 1)Relativelyfixedwelldemarcatedkeratoticanderythematousplaquesoverextensorsurfaces. 2)Transienterythematous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affe01c89c76a6051ee62c986231f22e