Zobrazeno 1 - 10
of 638
pro vyhledávání: '"A. V. Vlassov"'
Publikováno v:
Население и экономика, Vol 8, Iss 1, Pp 181-193 (2024)
Background. Rationing of health care—restricting patients’ access to potentially beneficial health care interventions through non-market instruments—is a natural feature of all health care systems as they operate under resource constraints. The
Externí odkaz:
https://doaj.org/article/495c8d8e82384bf4be8392050e0de231
Autor:
Ivan V. Chernikov, Irina K. Bachkova, Aleksandra V. Sen’kova, Mariya I. Meschaninova, Innokenty A. Savin, Valentin V. Vlassov, Marina A. Zenkova, Elena L. Chernolovskaya
Publikováno v:
Cells, Vol 13, Iss 9, p 767 (2024)
Small interfering RNA (siRNA) holds significant therapeutic potential by silencing target genes through RNA interference. Current clinical applications of siRNA have been primarily limited to liver diseases, while achievements in delivery methods are
Externí odkaz:
https://doaj.org/article/df86cd36ee1a45d0b8013056b41765d0
Autor:
Ivan V. Chernikov, Ul’yana A. Ponomareva, Mariya I. Meschaninova, Irina K. Bachkova, Valentin V. Vlassov, Marina A. Zenkova, Elena L. Chernolovskaya
Publikováno v:
Molecules, Vol 29, Iss 4, p 786 (2024)
Cholesterol siRNA conjugates attract attention because they allow the delivery of siRNA into cells without the use of transfection agents. In this study, we compared the efficacy and duration of silencing induced by cholesterol conjugates of selectiv
Externí odkaz:
https://doaj.org/article/a9812619882e4165812a0c26a5a07816
Autor:
Maxim S. Kupryushkin, Anton V. Filatov, Nadezhda L. Mironova, Olga A. Patutina, Ivan V. Chernikov, Elena L. Chernolovskaya, Marina A. Zenkova, Dmitrii V. Pyshnyi, Dmitry A. Stetsenko, Sidney Altman, Valentin V. Vlassov
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 211-226 (2022)
Antisense gapmer oligonucleotides containing phosphoryl guanidine (PG) groups, e.g., 1,3-dimethylimidazolidin-2-imine, at three to five internucleotidic positions adjacent to the 3′ and 5′ ends were prepared via the Staudinger chemistry, which is
Externí odkaz:
https://doaj.org/article/c83f7d0cf88a49389f1c3548b177f3e2
Publikováno v:
Journal of Public Health Research (2021)
Background: Poisoning is a critical public health problem. Toxic substances differ across time, region and age. Little is known about poisoning in Russia, and even less is known about lethal poisoning in children in Russia. We aimed to describe the c
Externí odkaz:
https://doaj.org/article/485355f90b5242db9331ab70c8de5e20
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Small double-stranded RNAs with certain sequence motifs are able to interact with pattern-recognition receptors and activate the innate immune system. Recently, we identified a set of short double-stranded 19-bp RNA molecules with 3-nucleotide 3′-o
Externí odkaz:
https://doaj.org/article/a7622dbb931c46e79269f161290b3e27
Autor:
Semyon S. Plis, Liliya A. Kovalenko, Olesya V. Veselkina, Dmitry M. Dolginov, Yury N. Ostapenko, Vasily V. Vlassov, Vladimir A. Klevno
Publikováno v:
Russian Journal of Forensic Medicine. 8:13-22
BACKGROUND: This study aimed to evaluate the differences in the clinical pictures in the group of alcohol intoxication (without the loss of conscious) and alcohol poisoning (with the loss of conscious). AIMS: This study aimed to investigate the clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67c3b8a6d930d159c278bb2fc5f05eb7
https://doi.org/10.17816/fm709
https://doi.org/10.17816/fm709
Autor:
Daniil V. Gladkikh, Aleksandra V. Sen′kova, Ivan V. Chernikov, Tatyana O. Kabilova, Nelly A. Popova, Valery P. Nikolin, Elena V. Shmendel, Mikhail A. Maslov, Valentin V. Vlassov, Marina A. Zenkova, Elena L. Chernolovskaya
Publikováno v:
Pharmaceutics, Vol 13, Iss 8, p 1252 (2021)
In this study, we examined the in vivo toxicity of the liposomes F consisting of 1,26-bis(cholest-5-en-3-yloxycarbonylamino)-7,11,16,20-tetraazahexacosan tetrahydrochloride, lipid-helper 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine and folate lipoco
Externí odkaz:
https://doaj.org/article/df1d1da4a6b245aa93611c072a0d6e74
Autor:
Ivan V. Chernikov, Daniil V. Gladkikh, Mariya I. Meschaninova, Alya G. Ven'yaminova, Marina A. Zenkova, Valentin V. Vlassov, Elena L. Chernolovskaya
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 6, Iss , Pp 209-220 (2017)
Chemical modifications are an effective way to improve the therapeutic properties of small interfering RNAs (siRNAs), making them more resistant to degradation in serum and ensuring their delivery to target cells and tissues. Here, we studied the car
Externí odkaz:
https://doaj.org/article/a745375785e3445691e0772e40b58dd1
Autor:
Julia A. Filippova, Anastasiya M. Matveeva, Evgenii S. Zhuravlev, Evgenia A. Balakhonova, Daria V. Prokhorova, Sergey J. Malanin, Raihan Shah Mahmud, Tatiana V. Grigoryeva, Ksenia S. Anufrieva, Dmitry V. Semenov, Valentin V. Vlassov, Grigory A. Stepanov
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
CRISPR technologies are nowadays widely used for targeted knockout of numerous protein-coding genes and for the study of various processes and metabolic pathways in human cells. Most attention in the genome editing field is now focused on the cleavag
Externí odkaz:
https://doaj.org/article/db7e89ffdcf348808cadf52f37b9b273