Zobrazeno 1 - 10
of 84
pro vyhledávání: '"A. V. Shidlovskii"'
Autor:
Chenglin Li, Xiaojie Zhu, Xinyue Sun, Xiaowei Guo, Wenzhe Li, Ping Chen, Yulii V. Shidlovskii, Qian Zhou, Lei Xue
Publikováno v:
Cell Division, Vol 18, Iss 1, Pp 1-16 (2023)
Abstract Background The c-Jun N-terminal kinase (JNK) pathway is an evolutionarily conserved regulator of cell death, which is essential for coordinating tissue homeostasis. In this study, we have characterized the Drosophila Ste20-like kinase Slik a
Externí odkaz:
https://doaj.org/article/02ec5040d0bd41d28223c38978a6c0e3
Autor:
Airat Ibragimov, Xin Yang Bing, Yulii V Shidlovskii, Michael Levine, Pavel Georgiev, Paul Schedl
Publikováno v:
eLife, Vol 12 (2023)
Though long non-coding RNAs (lncRNAs) represent a substantial fraction of the Pol II transcripts in multicellular animals, only a few have known functions. Here we report that the blocking activity of the Bithorax complex (BX-C) Fub-1 boundary is seg
Externí odkaz:
https://doaj.org/article/ca2098d62893426ca25ca2f8e2f03e71
Autor:
Oleg V. Bylino, Airat N. Ibragimov, Filomena Anna Digilio, Ennio Giordano, Yulii V. Shidlovskii
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
A transition from one developmental stage to another is accompanied by activation of developmental programs and corresponding gene ensembles. Changes in the spatial conformation of the corresponding loci are associated with this activation and can be
Externí odkaz:
https://doaj.org/article/04a3d52fbcd44d2096fca83dd9a267c2
Autor:
Eugene N. Kozlov, Roman V. Deev, Elena V. Tokmatcheva, Anna Tvorogova, Zaur M. Kachaev, Rudolf A. Gilmutdinov, Mariya Zhukova, Elena V. Savvateeva-Popova, Paul Schedl, Yulii V. Shidlovskii
Publikováno v:
Cells, Vol 12, Iss 13, p 1717 (2023)
Intracellular trafficking plays a critical role in the functioning of highly polarized cells, such as neurons. Transport of mRNAs, proteins, and other molecules to synaptic terminals maintains contact between neurons and ensures the transmission of n
Externí odkaz:
https://doaj.org/article/113e321edc534cb68cd76ede37f140a9
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Posttranscriptional gene regulation includes mRNA transport, localization, translation, and regulation of mRNA stability. CPEB (cytoplasmic polyadenylation element binding) family proteins bind to specific sites within the 3′-untranslated
Externí odkaz:
https://doaj.org/article/dcf2151029b64d2c938dba1392c95331
Autor:
Anna E. Pravednikova, Sergey Y. Shevchenko, Victor V. Kerchev, Manana R. Skhirtladze, Svetlana N. Larina, Zaur M. Kachaev, Alexander D. Egorov, Yulii V. Shidlovskii
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-19 (2020)
Abstract The hereditary aspect of obesity is a major focus of modern medical genetics. The genetic background is known to determine a higher-than-average prevalence of obesity in certain regions, like Oceania. There is evidence that dysfunction of br
Externí odkaz:
https://doaj.org/article/a51992179674408b863245d1ffa62e1f
Autor:
Eugene N. Kozlov, Elena V. Tokmatcheva, Anastasia M. Khrustaleva, Eugene S. Grebenshchikov, Roman V. Deev, Rudolf A. Gilmutdinov, Lyubov A. Lebedeva, Mariya Zhukova, Elena V. Savvateeva-Popova, Paul Schedl, Yulii V. Shidlovskii
Publikováno v:
Cells, Vol 12, Iss 2, p 318 (2023)
Activation of local translation in neurites in response to stimulation is an important step in the formation of long-term memory (LTM). CPEB proteins are a family of translation factors involved in LTM formation. The Drosophila CPEB protein Orb2 play
Externí odkaz:
https://doaj.org/article/8c81c77751544639a294a99f6877d87b
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
A constellation of chromosome conformation capture methods (С-methods) are an important tool for biochemical analysis of the spatial interactions between DNA regions that are separated in the primary sequence. All these methods are based on the long
Externí odkaz:
https://doaj.org/article/db78c7aeb0484cae8445ba4818125fe5
Autor:
Carla Bertapelle, Maria Rosaria Carillo, Nunzio Antonio Cacciola, Yulii V. Shidlovskii, Gianfranco Peluso, Filomena Anna Digilio
Publikováno v:
Molecules, Vol 27, Iss 10, p 3125 (2022)
Huntington’s disease (HD) is a dramatic neurodegenerative disorder caused by the abnormal expansion of a CAG triplet in the huntingtin gene, producing an abnormal protein. As it leads to the death of neurons in the cerebral cortex, the patients pri
Externí odkaz:
https://doaj.org/article/a9d75e5a08d649ba83835c79821544f1
Autor:
Zaur M. Kachaev, Sergey D. Ivashchenko, Eugene N. Kozlov, Lyubov A. Lebedeva, Yulii V. Shidlovskii
Publikováno v:
Cells, Vol 10, Iss 11, p 3239 (2021)
Components of the translation apparatus, including ribosomal proteins, have been found in cell nuclei in various organisms. Components of the translation apparatus are involved in various nuclear processes, particularly those associated with genome i
Externí odkaz:
https://doaj.org/article/b4767ed2378747278648884b1458ecba