Zobrazeno 1 - 10
of 1 760
pro vyhledávání: '"A. V. Schally"'
Autor:
Lin Du, Bo Man Ho, Linbin Zhou, Yolanda Wong Ying Yip, Jing Na He, Yingying Wei, Clement C. Tham, Sun On Chan, Andrew V. Schally, Chi Pui Pang, Jian Li, Wai Kit Chu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Dysregulation of Th17 cell differentiation and pathogenicity contributes to multiple autoimmune and inflammatory diseases. Previously growth hormone releasing hormone receptor (GHRH-R) deficient mice have been reported to be less susceptible
Externí odkaz:
https://doaj.org/article/f7cc99fe1f034fbb80b08ea07f7caf94
Autor:
Xiao Y. Tong, Hussain Hussain, Nagarajarao Shamaladevi, Michael D. Norenberg, Aya Fadel, Omar El Hiba, El got Abdeljalil, Bilal El-Mansoury, Deepak Kempuraj, Sampath Natarajan, Andrew V. Schally, Miklos Jaszberenyi, Luis Salgueiro, Michael J. Paidas, Arumugam R. Jayakumar
Publikováno v:
Biology, Vol 13, Iss 4, p 228 (2024)
Hepatic encephalopathy (HE) is a neurological condition linked to liver failure. Acute HE (Type A) occurs with acute liver failure, while chronic HE (Type C) is tied to cirrhosis and portal hypertension. HE treatments lag due to gaps in understanding
Externí odkaz:
https://doaj.org/article/be32dcb9f85c4c088e94bb026dcebcd2
Autor:
Giuseppina Granato, Iacopo Gesmundo, Francesca Pedrolli, Ramesh Kasarla, Laura Begani, Dana Banfi, Stefania Bruno, Tatiana Lopatina, Maria Felice Brizzi, Renzhi Cai, Wei Sha, Ezio Ghigo, Andrew V. Schally, Riccarda Granata
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
COVID-19 is characterized by an excessive inflammatory response and macrophage hyperactivation, leading, in severe cases, to alveolar epithelial injury and acute respiratory distress syndrome. Recent studies have reported that SARS-CoV-2 spike (S) pr
Externí odkaz:
https://doaj.org/article/b14e8e79b3464a86bf94ec27c014b375
Autor:
Lucia Recinella, Maria Loreta Libero, Serena Veschi, Anna Piro, Guya Diletta Marconi, Francesca Diomede, Annalisa Chiavaroli, Giustino Orlando, Claudio Ferrante, Rosalba Florio, Alessia Lamolinara, Renzhi Cai, Wei Sha, Andrew V. Schally, Roberto Salvatori, Luigi Brunetti, Sheila Leone
Publikováno v:
Cells, Vol 12, Iss 22, p 2615 (2023)
Growth hormone (GH)-releasing hormone (GHRH) has been suggested to play a crucial role in brain function. We aimed to further investigate the effects of a novel GHRH antagonist of the Miami (MIA) series, MIA-602, on emotional disorders and explore th
Externí odkaz:
https://doaj.org/article/176ee016bc7046c0a7ac5ff9c9711ebd
Autor:
Hao-Lin Ren, Ruiping Cai, Ruize Xue, Yaoxia Zhang, Qian Xu, Xianyang Zhang, RenZhi Cai, Wei Sha, Andrew V. Schally, Ming-Sheng Zhou
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionVascular calcification (VC) is an independent risk factor for cardiovascular diseases. VC increases mortality of all-causes. VC is one of most common cardiovascular complications in type II diabetes. So far, no therapy has been proven to
Externí odkaz:
https://doaj.org/article/a91dd026d7e041a0bf4e1cc7816a1aaa
Autor:
Herjan J.T. Coelingh Bennink, Jeroen A. van Moorselaar, E. David Crawford, Erik P.M. Roos, Diederik M. Somford, Ton A. Roeleveld, Tjard D. de Haan, Harm H.E. van Melick, Yacov Reisman, Yvette Zimmerman, Gonnie van Osta, Jan Krijgh, Neal D. Shore, Fred Saad, Andrew V. Schally, Frans M.J. Debruyne
Publikováno v:
European Urology Open Science, Vol 28, Iss , Pp 52-61 (2021)
Background: Androgen deprivation therapy (ADT) for prostate cancer with luteinizing hormone-releasing hormone (LHRH) agonists can be improved. Objective: To assess safety, the frequency and severity of hot flushes (HFs), bone health, and antitumor ef
Externí odkaz:
https://doaj.org/article/dc4f5a0c31044f3baa728ff536e9797f
Autor:
Lucia Recinella, Annalisa Chiavaroli, Valentina Di Valerio, Serena Veschi, Giustino Orlando, Claudio Ferrante, Iacopo Gesmundo, Riccarda Granata, Renzhi Cai, Wei Sha, Andrew V. Schally, Rossano Lattanzio, Luigi Brunetti, Sheila Leone
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Besides its metabolic and endocrine effects, growth hormone (GH)-releasing hormone (GHRH) is involved in the modulation of inflammation. Recently synthetized GHRH antagonist MIA-690 and MR-409, GHRH agonist, developed by us have shown potent
Externí odkaz:
https://doaj.org/article/182f84ae73e34728bf37d0224ab8d8f7
Autor:
Lucia Recinella, Annalisa Chiavaroli, Serena Veschi, Valentina Di Valerio, Rossano Lattanzio, Giustino Orlando, Claudio Ferrante, Iacopo Gesmundo, Riccarda Granata, Renzhi Cai, Wei Sha, Andrew V. Schally, Luigi Brunetti, Sheila Leone
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112554- (2022)
Colorectal cancer (CRC) is an aggressive tumor in which new treatment options deliver negative results on cure rates and long-term survival. The anticancer effects of growth hormone-releasing hormone (GHRH) antagonists have been reported in various e
Externí odkaz:
https://doaj.org/article/58b6c8b16cec4e3fbfbc6b81821877ac
Autor:
Dávid Fodor, Éva Pozsgai, Andrew V. Schally, Zoltán László, Éva Gömöri, Éva Szabó, László Rumi, Dorottya Lőcsei, Árpád Boronkai, Szabolcs Bellyei
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 719 (2023)
Background: Rectal cancer constitutes nearly one-third of all colorectal cancer diagnoses, and certain clinical and molecular markers have been studied as potential prognosticators of patient survival. The main objective of our study was to investiga
Externí odkaz:
https://doaj.org/article/8759efa106814de79e1b04c3600f0cd0
Autor:
Chongxu Zhang, Runxia Tian, Emilee M Dreifus, Abdolrazagh Hashemi Shahraki, Gregory Holt, Renzhi Cai, Anthony Griswold, Pablo Bejarano, Robert Jackson, Andrew V Schally, Mehdi Mirsaeidi
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 7, Pp n/a-n/a (2021)
Abstract Objectives Growth hormone‐releasing hormone (GHRH) is a potent stimulator of growth hormone (GH) secretion from the pituitary gland. Although GHRH is essential for the growth of immune cells, the regulatory effects of its antagonist in gra
Externí odkaz:
https://doaj.org/article/0dfbe8b684ab40c08ad80666e1fd067a