Zobrazeno 1 - 10
of 28
pro vyhledávání: '"A. V. Savinkova"'
Autor:
E. S. Lylova, A. V. Savinkova, E. M. Zhidkova, K. I. Kirsanov, M. G. Yakubovskaya, I. V. Budunova, E. A. Lesovaya
Publikováno v:
Сибирский онкологический журнал, Vol 19, Iss 6, Pp 73-81 (2020)
Glucocorticoids (GC ) have been an integral component of the treatment of leukemias and lymphomas for several decades. Specific cytotoxic effect of GC on transformed lymphoblasts mediates their use at the stage of the remission induction as well as c
Externí odkaz:
https://doaj.org/article/6ced8adb549c4e0883fcb15eaab92973
Autor:
A. V. Savinkova, E. M. Zhidkova, L. R. Tilova, M. D. Lavrova, E. S. Lylova, K. A. Kuzin, A. Yu. Portyannikova, V. P. Maximova, A. V. Kholodova, O. A. Vlasova, T. I. Fetisov, K. I. Kirsanov, G. A. Belitskiy, M. G. Yakubovskaya, E. A. Lesovaya
Publikováno v:
Сибирский онкологический журнал, Vol 17, Iss 3, Pp 77-87 (2018)
Recently many new approaches for repurposing or repositioning of the clinically used drugs have been developed. Drug repurposing allows not only to use known schemes for the synthesis of biologically active compounds, but also to avoid multiple studi
Externí odkaz:
https://doaj.org/article/e9faacf944904ba39f5c4fc1143a98e4
Autor:
E. M. Zhidkova, K. A. Kuzin, L. R. Tilova, A. V. Savinkova, O. I. Borisova, M. D. Lavrova, V. P. Maximova, K. I. Kirsanov, M. G. Yakubovskaya, E. A. Lesovaya
Publikováno v:
Сибирский онкологический журнал, Vol 16, Iss 6, Pp 41-46 (2017)
Glucocorticoids (GCs) are often used as an adjuvant therapy to reduce the adverse effects of chemotherapy in breast cancer patients. Moreover, GCs can display pro-proliferative or anti-proliferative effects on BC cells depending on their molecular su
Externí odkaz:
https://doaj.org/article/4d64a0da2fe24c45b32fe739585c115d
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 34-42 (2024)
Relevance. The complexity of diagnosing and treating autism spectrum disorders (ASD) is attributed to their unknown etiology and pathophysiology. The investigation of ASD models induced by sodium valproate (VPA) holds significant importance in the de
Externí odkaz:
https://doaj.org/article/3fae37b694694ff38560e1d9c334c38a
Autor:
Ekaterina M Zhidkova, Evgeniya S Lylova, Alena V Savinkova, Sergey A Mertsalov, Kirill I Kirsanov, Gennady A Belitsky, Marianna G Yakubovskaya, Ekaterina A Lesovaya
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 14 (2020)
Glucocorticoids (GCs) are stress hormones that play multiple roles in the regulation of cancer cell differentiation, apoptosis, and proliferation. Some types of cancers, such as hematological malignancies, can be effectively treated by GCs, whereas t
Externí odkaz:
https://doaj.org/article/acffbb957f7e4348834e8168b5fd0156
Autor:
Irina Budunova, Joel T. Dudley, Ben Readhead, Leo I. Gordon, Marianna G. Yakubovskaya, Gleb Baida, Anna Klopot, Kirill I. Kirsanov, Evgeny P. Kulikov, Ekaterina M. Zhidkova, Evgeniya S. Lylova, Olga V. Morozova, Alena V. Savinkova, Ekaterina A. Lesovaya
Supplementary Figures 1-9. Suppl. Fig. 1 contains quantification of Western blots. Suppl. Fig. 2 demonstrates the effect of PI3K/mTOR/Akt inhibitors on regulation of endogenous genes by Dex in CEM and Granta cells. Suppl. Fig. 3 shows cytotoxic effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c808766be15b7e58d5699c5e350e51
https://doi.org/10.1158/1535-7163.22520967.v1
https://doi.org/10.1158/1535-7163.22520967.v1
Autor:
Irina Budunova, Joel T. Dudley, Ben Readhead, Leo I. Gordon, Marianna G. Yakubovskaya, Gleb Baida, Anna Klopot, Kirill I. Kirsanov, Evgeny P. Kulikov, Ekaterina M. Zhidkova, Evgeniya S. Lylova, Olga V. Morozova, Alena V. Savinkova, Ekaterina A. Lesovaya
Glucocorticoids are widely used for therapy of hematologic malignancies. Unfortunately, chronic treatment with glucocorticoids commonly leads to adverse effects including skin and muscle atrophy and osteoporosis. We found recently that REDD1 (regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25793532674771734fa0c0e0b209e4a2
https://doi.org/10.1158/1535-7163.c.6542853.v1
https://doi.org/10.1158/1535-7163.c.6542853.v1
Autor:
Irina Budunova, Joel T. Dudley, Ben Readhead, Leo I. Gordon, Marianna G. Yakubovskaya, Gleb Baida, Anna Klopot, Kirill I. Kirsanov, Evgeny P. Kulikov, Ekaterina M. Zhidkova, Evgeniya S. Lylova, Olga V. Morozova, Alena V. Savinkova, Ekaterina A. Lesovaya
Supplementary Tables 1-3. Suppl. Table 1 contains the list of REDD1 inhibitors identified by computational screen and selected for study. Suppl. Table 2 contains primer sets for Q-PCR analysis. Suppl. Table 3 contains IC50 values of WM, LY294002 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e90a71d530b4556b7313a7c5c76578e
https://doi.org/10.1158/1535-7163.22520964.v1
https://doi.org/10.1158/1535-7163.22520964.v1
Autor:
Mikhail Y. Syromyatnikov, Mariya M. Isuwa, Olga V. Savinkova, Mariya I. Derevshchikova, Vasily N. Popov
Publikováno v:
Agriculture, Vol 10, Iss 3, p 79 (2020)
In recent decades an increase in the use of pesticides to protect plants from pests, diseases and weeds has been observed. There are many studies on the effects of various pesticides on non-target organisms. This review aims to analyze and summarize
Externí odkaz:
https://doaj.org/article/042f4a55a7f444009140a45de0c98472
Publikováno v:
Vestnik Voronežskogo Gosudarstvennogo Universiteta Inženernyh Tehnologij, Vol 82, Iss 4, Pp 54-59 (2021)
Currently, there is a trend in decreasing of the number of pollinators, which is already a matter of food security. Bumblebees Bombus terrestris L. are economically important pollinators of vegetables and other agricultural crops. Recently, it has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85275170ea839069e9e6b2aa42098939
https://www.vestnik-vsuet.ru/vguit/article/view/2598
https://www.vestnik-vsuet.ru/vguit/article/view/2598