Zobrazeno 1 - 10
of 58
pro vyhledávání: '"A. V. Pisliakov"'
Publikováno v:
Nucleic Acids Research
The RNA guanine-N7 methyltransferase (RNMT) in complex with RNMT-activating miniprotein (RAM) catalyses the formation of a N7-methylated guanosine cap structure on the 5′ end of nascent RNA polymerase II transcripts. The mRNA cap protects the prima
Autor:
Sarah A. Harris, Geoff Wells, Pedro J. Buigues, Magd Badaoui, Sam Alexander Martino, Andrei V. Pisliakov, Dénes Berta, Nadia Elghobashi-Meinhardt, Elisa Frezza, Edina Rosta
Publikováno v:
Chemical Science
Chemical Science, The Royal Society of Chemistry, 2021, ⟨10.1039/D1SC02775A⟩
Chemical Science, The Royal Society of Chemistry, 2021, ⟨10.1039/D1SC02775A⟩
The RNA helicase (non-structural protein 13, NSP13) of SARS-CoV-2 is essential for viral replication, and it is highly conserved among the coronaviridae family, thus a prominent drug target to treat COVID-19. We present here structural models and dyn
Autor:
Magd Badaoui, Dénes Berta, Sarah A. Harris, Geoff Wells, Pedro J. Buigues, Nadia Elghobashi-Meinhardt, Sam Alexander Martino, Andrei V. Pisliakov, Elisa Frezza, Edina Rosta
Having claimed over 1 million lives worldwide to date, the ongoing COVID-19 pandemic has created one of the biggest challenges to develop an effective drug to treat infected patients. Among all the proteins expressed by the virus, RNA helicase is a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e172868e57f2f19c40bc1b74db6f9919
https://doi.org/10.1101/2020.11.03.366609
https://doi.org/10.1101/2020.11.03.366609
Autor:
Mélanie Boeckstaens, Andrei V. Pisliakov, Paul A. Hoskisson, Gaëtan Dias Mirandela, Gordon Williamson, Arnaud Javelle, Anna Maria Marini, Ulrich Zachariae, Callum M. Ives, Adriana Bizior, Eilidh Terras, Marcus G Bage, Giulia Tamburrino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aa91694ed29c07b10643580a313d4a1
https://doi.org/10.7554/elife.57183.sa2
https://doi.org/10.7554/elife.57183.sa2
Autor:
Gaëtan Dias Mirandela, Mélanie Boeckstaens, Anna Maria Marini, Gordon Williamson, Ulrich Zachariae, Arnaud Javelle, Eilidh Terras, Marcus G Bage, Paul A. Hoskisson, Giulia Tamburrino, Andrei V. Pisliakov, Adriana Bizior, Callum M. Ives
Publikováno v:
eLife, 9
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
The transport of charged molecules across biological membranes faces the dual problem of accommodating charges in a highly hydrophobic environment while maintaining selective substrate translocation. This has been the subject of a particular controve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4509b08625035b44c9f64c776a81235
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/313028
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/313028
1AbstractRecruitment of the mRNA Capping Enzyme (CE/RNGTT) to the site of transcription is essential for the formation of the 5’ mRNA cap, which in turn ensures efficient transcription, splicing, polyadenylation, nuclear export and translation of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793c7d637730eda26b93b2fd7bbe0097
https://doi.org/10.1101/2020.02.25.964700
https://doi.org/10.1101/2020.02.25.964700
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 8, p e1002674 (2012)
Nitric oxide reductases (NORs) are membrane proteins that catalyze the reduction of nitric oxide (NO) to nitrous oxide (N(2)O), which is a critical step of the nitrate respiration process in denitrifying bacteria. Using the recently determined first
Externí odkaz:
https://doaj.org/article/947add0f42fc44cc9d356b2ff5f3c8f2
Publikováno v:
Biochemical and Biophysical Research Communications. 491:47-52
Cytochrome cbb3 (or C-type) oxidases are a highly divergent group and the least studied members of the heme-copper oxidases (HCOs) superfamily. HCOs couple the reduction of oxygen at the end of the respiratory chain to the active proton translocation
Autor:
A. V. Pisliakov, G.Yu. Grigoriev, Andrey Sokolov, Sh. Sh. Nabiev, A. S. Lagutin, Alexei Vasiliev, Nikolay Samotaev
Publikováno v:
Acta Astronautica. 135:76-82
A fairly reliable method of fire detection at an early stage is suggested and proved. The method is based on the monitoring of the air chemical composition, which changes strongly due to thermal decomposition (pyrolysis) of overheated combustible mat
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1858:396-406
Heme-copper oxidases are membrane protein complexes that catalyse the final step of the aerobic respiration, namely the reduction of oxygen to water. The energy released during catalysis is coupled to the active translocation of protons across the me