Zobrazeno 1 - 10
of 190
pro vyhledávání: '"A. V. Pindyurin"'
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 27, Iss 7, Pp 906-915 (2023)
CHO cells are most commonly used for the synthesis of recombinant proteins in biopharmaceutical production. When stable producer cell lines are obtained, the locus of transgene integration into the genome has a great influence on the level of its exp
Externí odkaz:
https://doaj.org/article/94b243e0ceef45838f0bbe9a68c5c051
Autor:
Veniamin Fishman, Alexey V Pindyurin
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/f0619c2052f0403fae82dac34933ef9f
Autor:
Alexander A. Dolskiy, Andrey A. Yarushkin, Irina V. Grishchenko, Natalya A. Lemskaya, Alexey V. Pindyurin, Lidiya V. Boldyreva, Vladimir O. Pustylnyak, Dmitry V. Yudkin
Publikováno v:
Non-coding RNA Research, Vol 6, Iss 1, Pp 1-7 (2021)
FRAXopathies are caused by the expansion of the CGG repeat in the 5′UTR of the FMR1 gene, which encodes the protein responsible for the synthesis of FMRP. This mutation leads to dramatic changes in FMRP expression at both the mRNA and protein level
Externí odkaz:
https://doaj.org/article/b7bf439764c74c6aac61b6cf5c21185f
Autor:
Alyona V. Razuvaeva, Lucia Graziadio, Valeria Palumbo, Gera A. Pavlova, Julia V. Popova, Alexey V. Pindyurin, Silvia Bonaccorsi, Maria Patrizia Somma, Maurizio Gatti
Publikováno v:
Cells, Vol 12, Iss 6, p 922 (2023)
The Drosophila abnormal spindle (asp) gene was discovered about 40 years ago and shown to be required for both mitotic and meiotic cell division. Subsequent studies showed that asp is highly conserved and that mutations in its human ortholog ASPM (Ab
Externí odkaz:
https://doaj.org/article/b292e45b999142e0be2b9736be985ba5
Autor:
Anna A. Ogienko, Evgeniya N. Andreyeva, Evgeniya S. Omelina, Anastasiya L. Oshchepkova, Alexey V. Pindyurin
Publikováno v:
BMC Genetics, Vol 21, Iss S1, Pp 1-11 (2020)
Abstract Background The Drosophila central nervous system (CNS) is a convenient model system for the study of the molecular mechanisms of conserved neurobiological processes. The manipulation of gene activity in specific cell types and subtypes of th
Externí odkaz:
https://doaj.org/article/37ffbf2f062249189bde973034b2bed2
Publikováno v:
BMC Genomics, Vol 20, Iss S7, Pp 1-10 (2019)
Abstract Background Massively parallel reporter assays (MPRAs) enable high-throughput functional evaluation of various DNA regulatory elements and their mutant variants. The assays are based on construction of highly diverse plasmid libraries contain
Externí odkaz:
https://doaj.org/article/ae2faaa1610d41db9ffeb8a9878a9bf9
Autor:
Santiago Gisler, Joana P. Gonçalves, Waseem Akhtar, Johann de Jong, Alexey V. Pindyurin, Lodewyk F. A. Wessels, Maarten van Lohuizen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Designing effective genome engineering strategies requires an understanding of the impact that genomic locus has on CRISPR-Cas9 activity. Here the authors use TRIP integrations to profile editing outcomes genome-wide and observe that gRNA sequence in
Externí odkaz:
https://doaj.org/article/8cafb83aa5a34b2b9543a0254a16b6e2
Autor:
Gera A. Pavlova, Alyona V. Razuvaeva, Julia V. Popova, Evgeniya N. Andreyeva, Lyubov A. Yarinich, Mikhail O. Lebedev, Claudia Pellacani, Silvia Bonaccorsi, Maria Patrizia Somma, Maurizio Gatti, Alexey V. Pindyurin
Publikováno v:
BMC Molecular and Cell Biology, Vol 20, Iss S1, Pp 1-13 (2019)
Abstract Background The calmodulin-regulated spectrin-associated proteins (CAMSAPs) belong to a conserved protein family, which includes members that bind the polymerizing mcrotubule (MT) minus ends and remain associated with the MT lattice formed by
Externí odkaz:
https://doaj.org/article/82654c3f397a41b3a69ffb2e63979cb8
Autor:
Evgeniya N. Andreyeva, Anna A. Ogienko, Tatiana D. Dubatolova, Anastasiya L. Oshchepkova, Elena N. Kozhevnikova, Anton V. Ivankin, Gera A. Pavlova, Sergei A. Kopyl, Alexey V. Pindyurin
Publikováno v:
BMC Genetics, Vol 20, Iss S1, Pp 15-23 (2019)
Abstract Background Expression of the CNDP2 gene is frequently up- or down-regulated in different types of human cancers. However, how the product of this gene is involved in cell growth and proliferation is poorly understood. Moreover, our knowledge
Externí odkaz:
https://doaj.org/article/297d4be63a424110b06069fe6364bdfb
Autor:
E. N. Andreyeva, A. A. Ogienko, A. A. Yushkova, J. V. Popova, G. A. Pavlova, E. N. Kozhevnikova, A. V. Ivankin, M. Gatti, A. V. Pindyurin
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 23, Iss 2, Pp 190-198 (2019)
The nucleolus is a dynamic non-membrane-bound nuclear organelle, which plays key roles not only in ribosome biogenesis but also in many other cellular processes. Consistent with its multiple functions, the nucleolus has been implicated in many human
Externí odkaz:
https://doaj.org/article/6a68bd9357b7490188c8deb6fc520616