Zobrazeno 1 - 10
of 10
pro vyhledávání: '"A. V. Lyubitelev"'
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 2, Pp 30-41 (2023)
Genetic apparatus of human cells is constantly affected by a broad spectrum of mutagenic factors, both exogenous and endogenous. Genetic and epigenetic disorders, which emerge as a result of this influence, become the main cause of the majority of ma
Externí odkaz:
https://doaj.org/article/afaf993f0c09406297b6ebe7ff848498
Autor:
Omar L. Kantidze, Artem V. Luzhin, Ekaterina V. Nizovtseva, Alfiya Safina, Maria E. Valieva, Arkadiy K. Golov, Artem K. Velichko, Alexander V. Lyubitelev, Alexey V. Feofanov, Katerina V. Gurova, Vasily M. Studitsky, Sergey V. Razin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Curaxins are a recently discovered class of anti-cancer agents that disturbs DNA/histone interactions within. Here the authors provide evidence that curaxins affect the spatial genome organization and compromise enhancer-promoter communication necess
Externí odkaz:
https://doaj.org/article/6ad5ed2c5629478aaf374797be05a1e6
Autor:
Han-Wen Chang, Alexey V. Feofanov, Alexander V. Lyubitelev, Grigory A. Armeev, Elena Y. Kotova, Fu-Kai Hsieh, Mikhail P. Kirpichnikov, Alexey K. Shaytan, Vasily M. Studitsky
Publikováno v:
Cells, Vol 11, Iss 16, p 2475 (2022)
Histone N-terminal tails and their post-translational modifications affect various biological processes, often in a context-specific manner; the underlying mechanisms are poorly studied. Here, the role of individual N-terminal tails of histones H2A/H
Externí odkaz:
https://doaj.org/article/93606d7b46b7459aa3494a6bed92aa5b
Autor:
Tatiana Andreeva, Alexey V. Feofanov, Mikhail P. Kirpichnikov, Vasily M. Studitsky, A. V. Lyubitelev, N. V. Malyuchenko
Publikováno v:
Moscow University Biological Sciences Bulletin. 76:118-122
Mononucleosomes assembled using DNA templates of various lengths that contain a nucleosome-positioning sequence are widely used in molecular biological studies, but their structural features require detailed investigation. The single-particle fluores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27ae3a3c69cd4ccc775031ca6fc6b61d
https://doi.org/10.3103/s0096392521030019
https://doi.org/10.3103/s0096392521030019
Publikováno v:
Russian Journal of Bioorganic Chemistry. 47:278-287
Linker histones are DNA-binding architectural chromatin proteins involved in the formation of supranucleosomal levels of chromatin packaging. In mammals, 11 variants of these proteins are known, but the functional significance of this diversity is cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8d1ac72601deef989fab2d8e65db76c
https://doi.org/10.1134/s1068162021010143
https://doi.org/10.1134/s1068162021010143
Autor:
A. V. Lyubitelev, Vasily M. Studitsky, Elena Bondarenko, Tatiana Andreeva, Alexey V. Feofanov
Publikováno v:
Microscopy and Microanalysis. 27:1740-1741
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a344841bc1d9c3a68ae58bdbbf6e3f4
https://doi.org/10.1017/s143192762100636x
https://doi.org/10.1017/s143192762100636x
Publikováno v:
Moscow University Biological Sciences Bulletin. 72:146-150
The chromatin structure and DNA accessibility to proteins depend on the structure of linker DNA entering and exiting the nucleosome. Since DNA is a negatively charged polymer, the conformation of linker DNA, in turn, depends on the ionic microenviron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3f7fd0d64d0de348dfa0b7b3dd1ea50
https://doi.org/10.3103/s0096392517030075
https://doi.org/10.3103/s0096392517030075
Autor:
Artem V. Luzhin, Alfiya Safina, Alexey V. Feofanov, A. V. Lyubitelev, Katerina Gurova, Omar L. Kantidze, Artem K. Velichko, Sergey V. Razin, Vasily M. Studitsky, Arkadiy K. Golov, Ekaterina V. Nizovtseva, M. E. Valieva
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Recently we characterized a class of anti-cancer agents (curaxins) that disturbs DNA/histone interactions within nucleosomes. Here, using a combination of genomic and in vitro approaches, we demonstrate that curaxins strongly affect spatial genome or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541d293b2878aadbd83ea1baa053575a
https://doi.org/10.1038/s41467-019-09500-7
https://doi.org/10.1038/s41467-019-09500-7
Autor:
Alexey V. Feofanov, Mikhail P. Kirpichnikov, O. V. Chertkov, Vasily M. Studitsky, N. V. Malyuchenko, M. S. Mikhaylova, A. V. Lyubitelev, K.S. Kudryashova
Publikováno v:
Moscow University Biological Sciences Bulletin. 71:108-113
A method for fluorescently labeled DNA synthesis, which makes it possible to assemble mononucleosomes with 40 bp linkers, was developed. Cy3 and Cy5 labels were introduced into the linkers at distances of 10 bp before the first nucleotide and 15 bp a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::194c0843c8445419103e1ea0965f428e
https://doi.org/10.3103/s0096392516020061
https://doi.org/10.3103/s0096392516020061
Autor:
Vasily M. Studitsky, Alexey K. Shaytan, A. V. Lyubitelev, D. V. Nikitin, Mikhail P. Kirpichnikov
Publikováno v:
Biochemistry (Moscow). 81:213-223
Linker histones such as variants H1, H5, and other similar proteins play an important role in regulation of chromatin structure and dynamics. However, interactions of linker histones with DNA and proteins, as well as specific functions of their diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c470211f128f508502b5ea9b48cbebb
https://doi.org/10.1134/s0006297916030032
https://doi.org/10.1134/s0006297916030032