Zobrazeno 1 - 10
of 29
pro vyhledávání: '"A. V. Khrunin"'
Autor:
Ivan B. Filippenkov, Andrey V. Khrunin, Ivan V. Mozgovoy, Lyudmila V. Dergunova, Svetlana A. Limborska
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2727 (2023)
Complex diseases that affect the functioning of the central nervous system pose a major problem for modern society. Among these, ischemic stroke (IS) holds a special place as one of the most common causes of disability and mortality worldwide. Furthe
Externí odkaz:
https://doaj.org/article/b4d8d3ed348843bbae1241fbf2e22ae5
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15355 (2023)
The genetic architecture of ischemic stroke (IS), which is one of the leading causes of death worldwide, is complex and underexplored. The traditional approach for associative gene mapping is genome-wide association studies (GWASs), testing individua
Externí odkaz:
https://doaj.org/article/14478a68e45a4169b1e40975fc093085
Autor:
Andrey V. Khrunin, Gennady V. Khvorykh, Anna S. Arapova, Anna E. Kulinskaya, Evgeniya A. Koltsova, Elizaveta A. Petrova, Ekaterina I. Kimelfeld, Svetlana A. Limborska
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6831 (2023)
To date, there has been great progress in understanding the genetic basis of ischemic stroke (IS); however, several aspects of the condition remain underexplored, including the influence of genetic factors on post-stroke outcomes and the identificati
Externí odkaz:
https://doaj.org/article/f77ab8600f0640db8d3c209a0368165b
Autor:
Gennady V. Khvorykh, Andrey V. Khrunin
Publikováno v:
BMC Bioinformatics, Vol 21, Iss S12, Pp 1-14 (2020)
Abstract Background The imputation of genotypes increases the power of genome-wide association studies. However, the imputation quality should be assessed in each particular case. Nevertheless, not all imputation softwares control the error of output
Externí odkaz:
https://doaj.org/article/45a9ba10d3c0418ebf172c57ff3024b3
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228778 (2020)
Natural selection of beneficial genetic variants played a critical role in human adaptation to a wide range of environmental conditions. Northern Eurasia, despite its severe climate, is home to lots of ethnically diverse populations. The genetic vari
Externí odkaz:
https://doaj.org/article/db57d164c1c24d89a6067e36d1ebe2f9
Autor:
Gennady V. Khvorykh, Oleh A. Mulyar, Larisa Fedorova, Andrey V. Khrunin, Svetlana A. Limborska, Alexei Fedorov
Publikováno v:
Biology, Vol 9, Iss 11, p 392 (2020)
We performed an exhaustive pairwise comparison of whole-genome sequences of 3120 individuals, representing 232 populations from all continents and seven prehistoric people including archaic and modern humans. In order to reveal an intricate picture o
Externí odkaz:
https://doaj.org/article/aa86710c11564100b6180616a7172ccd
Autor:
Svetlana A. Limborska, Vasily V Stavchansky, Gennady V. Khvorykh, Ivan B. Filippenkov, Andrey V Khrunin, L.V. Dergunova
Publikováno v:
Genes, Vol 12, Iss 328, p 328 (2021)
Genes
Volume 12
Issue 3
Genes
Volume 12
Issue 3
In this paper we propose a workflow for studying the genetic architecture of ischemic stroke outcomes. It develops further the candidate gene approach. The workflow is based on the animal model of brain ischemia, comparative genomics, human genomic v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b926f02508dff5604427269436d7d7bd
https://www.mdpi.com/2073-4425/12/3/328
https://www.mdpi.com/2073-4425/12/3/328
Autor:
Andrey V Khrunin, Denis V Khokhrin, Irina N Filippova, Tõnu Esko, Mari Nelis, Natalia A Bebyakova, Natalia L Bolotova, Janis Klovins, Liene Nikitina-Zake, Karola Rehnström, Samuli Ripatti, Stefan Schreiber, Andre Franke, Milan Macek, Veronika Krulišová, Jan Lubinski, Andres Metspalu, Svetlana A Limborska
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58552 (2013)
Several studies examined the fine-scale structure of human genetic variation in Europe. However, the European sets analyzed represent mainly northern, western, central, and southern Europe. Here, we report an analysis of approximately 166,000 single
Externí odkaz:
https://doaj.org/article/e9a30dda50d04c20ac9017c9cc9c28dc
Autor:
Svetlana A. Limborska, A. V. Khrunin, A.O. Abaildayev, Dauren Botbayev, N. A. Aitkhozhina, Ayaz Belkozhaev, Yeldar Ashirbekov, D. D. Mukushkina, M. B. Rakhimgozhin
Publikováno v:
Molecular Genetics, Microbiology and Virology. 33:91-96
Historically, the Kazakhs formed through an amalgam of nomadic tribes that previously belonged to the Golden Horde. The Kazakh tribes were geographically divided into three tribal associations—the Great, the Middle, and the Lesser zhuzes. One of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f865dcca7452e17cf8f1aa7ed40c072d
https://doi.org/10.3103/s0891416818020040
https://doi.org/10.3103/s0891416818020040
Autor:
Larisa Fedorova, Andrey V Khrunin, Oleh A Mulyar, Svetlana A. Limborska, Gennady V. Khvorykh, Alexei Fedorov
Publikováno v:
Biology, Vol 9, Iss 392, p 392 (2020)
Biology
Volume 9
Issue 11
Biology
Volume 9
Issue 11
We performed an exhaustive pairwise comparison of whole-genome sequences of 3120 individuals, representing 232 populations from all continents and seven prehistoric people including archaic and modern humans. In order to reveal an intricate picture o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c425eb706f2b51e84b7b7200abb73cca
https://doi.org/10.3390/biology9110392
https://doi.org/10.3390/biology9110392