Zobrazeno 1 - 10
of 67
pro vyhledávání: '"A. V. Bol'but"'
Autor:
Natalia A. Syrota, A. V. Bol’but, Mykhailo V. Vovk, Igor I. Chernobaev, Oleksandr S. Liavinets, Sergiy V. Kemskiy
Publikováno v:
Chemistry of Heterocyclic Compounds. 57:841-847
4-(N-Boc-amino)-1Н-1,2,3-triazolecarbothioamides, obtained by a sequential treatment of 4-(N-Boc-amino)-1Н-1,2,3-triazoles with n-BuLi and alkyl isothiocyanates at –78÷–60°C, reacted with ethyl bromoacetate, forming the respective 4-(N-Boc-am
Autor:
Maxim А. Nechayev, Nazar M. Tsizorik, Yevhenii V. Hrynyshyn, A. V. Bol’but, M. V. Vovk, Anna R. Musiychuk
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:1554-1559
Methylpyrazolo[1,5-a]pyrazine-4-carboxylates were synthesized by palladium-catalyzed carbonylation of 4-chloropyrazolo[1,5-a]-pyrazines at elevated pressure and converted via nitrile intermediates to the corresponding amidoximes and amidines. Cycloco
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:1048-1053
4-(N-Boc-amino)-1,2,3-triazole-5-carbaldehydes upon heating under reflux in acetic acid in the presence of pyrrolidine react with cycloalkanones, acetylacetone, 1,3-cyclohexanediones, and malononitrile resulting in annulation of the pyridine ring wit
Autor:
Georgiy G. Yakovenko, A. V. Bol’but, Marta S. Yagodkina-Yakovenko, Oleh А. Lukianov, M. V. Vovk
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:347-354
1-Alkyl-N-Boc-5-formylpyrazol-4-amines react with malononitrile and cyanoacetamide to form 5-amino-1H-pyrazolo[4,3-b]pyridine nitriles and amides, respectively. Cyclocondensation of the obtained derivatives with chloroacetaldehyde, bromotrifluoroacet
Publikováno v:
Chemistry of Heterocyclic Compounds. 55:1211-1216
N-Boc-protected 5-formyl-1H-pyrazol-4-amines react with malonic acid in pyridine in the presence of pyrrolidine at 45–50°С or with malonic acid monomethyl ether in the presence of pyrrolidine in AcOH under reflux with the formation of 5-oxo-4,5-d
Publikováno v:
Chemistry of Heterocyclic Compounds. 55:1070-1074
4-Bromopyrazolo[1,5-a]pyrazines react with aryl(hetaryl)boronic acids in the presence of catalytic amounts of Pd(dppf)Cl2·CH2Cl2 and an excess of Cs2CO3 in the MeCN–H2O, 9:1 solvent system with the formation of 4-aryl(hetaryl)pyrazolo[1,5-a]pyrazi
Publikováno v:
Chemistry of Heterocyclic Compounds. 55:1092-1097
The corresponding ethyl 5-carbonylglycinates were synthesized by condensation of 4-(Boc-amino)-1,2,3-triazole-5-carboxylic acids with ethyl glycinate hydrochloride. They were intramolecularly cyclized with the selective formation of 1,4,6,7-tetrahydr
Publikováno v:
Chemistry of Heterocyclic Compounds. 55:893-896
A reaction of 4-chloropyrazolo[1,5-a]pyrazines with tert-butyl cyanoacetate proceeded via the formation of tert-butyl cyano(pyrazolo- [1,5-a]pyrazin-4(5H)-ylidene)ethanoates as intermediates and led to pyrazolo[1,5-a]pyrazin-4-ylacetonitriles, which
Publikováno v:
Chemistry of Heterocyclic Compounds. 55:379-385
N-Boc-4-aminopyrazole-5-carbaldehydes reacted with aryl, hetaryl, alkyl, and cycloalkyl ketones containing methylene groups. The reactions were accomplished in refluxing acetic acid in the presence of pyrrolidine and resulted in the formation of 5-su
Publikováno v:
Journal of Organic and Pharmaceutical Chemistry. 16:28-33
Aim. To study the conditions for reduction of 5-hydroxy[1,2,3]triazolo[4,5-e][1,4]diazepines and develop the method for the synthesis of their tetra- and hexahydroderivatives.Results and discussion. It has been found that the functional hydroxy and c