Zobrazeno 1 - 10
of 12
pro vyhledávání: '"A. V. Aydakova"'
Autor:
D. O. Shatalov, K. N. Trachuk, A. V. Aydakova, D. A. Akhmedova, I. S. Ivanov, D. S. Minenkov, I. Yu. Blazhevich, S. A. Kedik
Publikováno v:
Тонкие химические технологии, Vol 18, Iss 3, Pp 265-279 (2023)
Objectives. The study set out to use mathematical modeling, in particular the method of multifactorial analysis of multicriteria optimization (MAMO), in the development of a pharmaceutical product.Methods. After carrying out experimental tests based
Externí odkaz:
https://doaj.org/article/c10d2003d37c4710aaba1afe43b0f68a
Autor:
D. A. Akhmedova, D. O. Shatalov, I. S. Ivanov, A. V. Aydakova, A. Herbst, L. Greiner, A. P. Kaplun, A. S. Zhurbenko, S. A. Kedik
Publikováno v:
Тонкие химические технологии, Vol 16, Iss 4, Pp 307-317 (2021)
Objectives. To develop a method for the microfluidic synthesis of oligohexamethylene guanidine salts in a flow-type reactor and to evaluate its effectiveness in relation to the synthesis in a traditional capacitive reactor and compare the purities of
Externí odkaz:
https://doaj.org/article/a924b4c0779b4f8b916c740fbf5b2c58
Autor:
I. S. Ivanov, D. O. Shatalov, S. A. Kedik, I. P. Sedishev, N. E. Grammatikova, A. V. Aydakova, K. N. Trachuk, E. I. Yazykova
Publikováno v:
Антибиотики и Химиотерапия, Vol 64, Iss 11-12, Pp 8-15 (2020)
The acquisition of resistance to the antibiotics and antibacterial agents used by microorganisms sets the task of finding new active disinfectants. It is known that compounds of the oligoguanidine class possess pronounced antibacterial properties, lo
Externí odkaz:
https://doaj.org/article/8599124e6c1548268a99c91b65188219
Autor:
Denis O. Shatalov, Stanislav A. Kedik, Ivan S. Ivanov, Anna V. Aydakova, Diana A. Akhmedova, Dmitrii S. Minenkov, Sergei V. Beliakov, Alexander Herbst, Lasse Greiner, Liubov I. Kozlovskaya, Viktor P. Volok
Publikováno v:
Molecules, Vol 26, Iss 11, p 3472 (2021)
This paper reports the synthesis of branched alkylene guanidines using microfluidic technologies. We describe the preparation of guanidine derivatives at lower temperatures, and with significantly less time than that required in the previously applic
Externí odkaz:
https://doaj.org/article/7041cedbf18343128224aab21a450683
Autor:
Denis O. Shatalov, Stanislav A. Kedik, Alexey V. Panov, Elena S. Zhavoronok, Anna V. Aydakova, Alena V. Kovalenko, Olga A. Morozova, Irina M. Makeeva, Viktoria A. Dezhurko-Korol
Publikováno v:
Russian Open Medical Journal, Vol 7, Iss 3, p e0309 (2018)
The present work is devoted to study of the antimicrobial activity of a new promising synthetic biocidal compound, branched oligohexamethylene guanidine hydrochloride. The studies were carried out using optional anaerobic bacteria Staphylococcus aure
Externí odkaz:
https://doaj.org/article/8946b47aed614fdcb7b62b8fb84d8366
Autor:
S. V. Beliakov, D. O. Shatalov, V. N. Aldobaev, I. S. Ivanov, A. V. Aydakova, D. A. Akhmedova, S. A. Kedik
Publikováno v:
Drug Development and Industrial Pharmacy. 47:1764-1774
Branched oligohexamethyleneguanidine hydrochloride (branched OHMG-HC) possesses high biocidal activity. This study aimed at evaluating the pharmacokinetics of branched OHMG-HC and is mandatory for obtaining permission to conduct clinical studies. The
Autor:
A. V. Aydakova, I. S. Ivanov, S. A. Kedik, A.P. Kaplun, L. Greiner, D. O. Shatalov, Diana A. Akhmedova, A. S. Zhurbenko, A. Herbst
Publikováno v:
Тонкие химические технологии, Vol 16, Iss 4, Pp 307-317 (2021)
Objectives. To develop a method for the microfluidic synthesis of oligohexamethylene guanidine salts in a flow-type reactor and to evaluate its effectiveness in relation to the synthesis in a traditional capacitive reactor and compare the purities of
Autor:
Sergei V. Beliakov, Viktor P. Volok, I. S. Ivanov, A. V. Aydakova, S. A. Kedik, D. O. Shatalov, Dmitrii S. Minenkov, Diana A. Akhmedova, Lasse Greiner, Liubov I. Kozlovskaya, Alexander Herbst
Publikováno v:
Molecules
Volume 26
Issue 11
Molecules, Vol 26, Iss 3472, p 3472 (2021)
Volume 26
Issue 11
Molecules, Vol 26, Iss 3472, p 3472 (2021)
This paper reports the synthesis of branched alkylene guanidines using microfluidic technologies. We describe the preparation of guanidine derivatives at lower temperatures, and with significantly less time than that required in the previously applic
Publikováno v:
Drug development and industrial pharmacy. 46(9)
Branched oligohexamethyleneguanidine hydrochloride (OHMG) possesses great potential for the development of novel drugs for the treatment of diseases caused by bacteria. This study aimed at evaluating the antimicrobial activity of OHMG against potenti
Autor:
I. S. Ivanov, A. S. Evseeva, S. I. Biryulin, A. V. Kovalenko, E. N. Mikhailenko, S. V. Beliakov, E. S. Zhavoronok, D. O. Shatalov, S. A. Kedik, A. V. Aydakova
Publikováno v:
Polymer Science, Series D. 10:293-299
The review presents data regarding the main classes of substances applied in pharmaceutics for long-term control of pathogenic microflora. The problems of application of these substances caused by the resistance of pathogenic microflora to the main c