Zobrazeno 1 - 10
of 71
pro vyhledávání: '"A. V. Aralov"'
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 8, Pp 6851-6879 (2023)
The search for new drugs has been greatly accelerated by the emergence of new viruses and drug-resistant strains of known pathogens. Nucleoside analogues (NAs) are a prospective class of antivirals due to known safety profiles, which are important fo
Externí odkaz:
https://doaj.org/article/9efd0c19f32a49179b974caf2c13fb05
Akademický článek
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Autor:
Yue Wu, Zhenling Cui, Yen-Hua Huang, Simon J. de Veer, Andrey V. Aralov, Zhong Guo, Shayli V. Moradi, Alexandra O. Hinton, Jennifer R. Deuis, Shaodong Guo, Kai-En Chen, Brett M. Collins, Irina Vetter, Volker Herzig, Alun Jones, Matthew A. Cooper, Glenn F. King, David J. Craik, Kirill Alexandrov, Sergey Mureev
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Generic approach for rapid prototyping is essential for the progress of synthetic biology. Here the authors modify the cell-free translation system to control protein aggregation and folding and validate the approach by using single conditions for pr
Externí odkaz:
https://doaj.org/article/4f078ffc82bf47b0b496a47fa5dcdbdc
Autor:
Anna A. Rubekina, Polina N. Kamzeeva, Vera A. Alferova, Elena Yu. Shustova, Ekaterina S. Kolpakova, Elizaveta V. Yakovchuk, Evgenia V. Karpova, Maria O. Borodulina, Evgeny S. Belyaev, Alexei A. Khrulev, Vladimir A. Korshun, Evgeny A. Shirshin, Liubov I. Kozlovskaya, Andrey V. Aralov
Publikováno v:
Biomolecules, Vol 12, Iss 11, p 1609 (2022)
Rose Bengal (RB) is an anionic xanthene dye with multiple useful biological features, including photosensitization properties. RB was studied extensively as a photosensitizer, mostly for antibacterial and antitumor photodynamic therapy (PDT). The app
Externí odkaz:
https://doaj.org/article/278dc12c49594a5595281dca73dc49e1
Autor:
Vladimir B. Tsvetkov, Timofei S. Zatsepin, Anton V. Turaev, Valentina M. Farzan, Galina E. Pozmogova, Andrey V. Aralov, Anna M. Varizhuk
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 527-536 (2019)
I-motif structures, adopted by cytosine-rich DNA strands, have attracted considerable interest as possible regulatory elements in genomes. Applied science exploits the advantages of i-motif stabilization under acidic conditions: i-motif-based pH sens
Externí odkaz:
https://doaj.org/article/42b74ec692d54b3a9b30b26a15aed2b7
Autor:
Anna A. Shtro, Anzhelika V. Garshinina, Vera A. Alferova, Polina N. Kamzeeva, Viktor P. Volok, Ekaterina S. Kolpakova, Timofei D. Nikitin, Alexey A. Chistov, Evgeny S. Belyaev, Vladimir A. Korshun, Liubov I. Kozlovskaya, Andrey V. Aralov
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1178 (2022)
Perylene-based compounds are attracting significant attention due to their high broad-spectrum antiviral activity against enveloped viruses. Despite unambiguous results of in vitro studies and high selectivity index, the poor water solubility of thes
Externí odkaz:
https://doaj.org/article/7f114caa3ddf49d2805f8d4a93c6bd5c
Autor:
Oksana S Bychenko, Alexei A Khrulev, Julia I Svetlova, Vladimir B Tsvetkov, Polina N Kamzeeva, Yulia V Skvortsova, Boris S Tupertsev, Igor A Ivanov, Leonid V Aseev, Yuriy M Khodarovich, Evgeny S Belyaev, Liubov I Kozlovskaya, Timofei S Zatsepin, Tatyana L Azhikina, Anna M Varizhuk, Andrey V Aralov
Publikováno v:
Nucleic Acids Research. 51:2586-2601
Progress in RNA metabolism and function studies relies largely on molecular imaging systems, including those comprising a fluorogenic dye and an aptamer-based fluorescence-activating tag. G4 aptamers of the Mango family, typically combined with a dup
Autor:
Nataliia A. Petrunina, Alina S. Shtork, Maria M. Lukina, Vladimir B. Tsvetkov, Yuri M. Khodarovich, Alexey V. Feofanov, Anastasia M. Moysenovich, Eugene G. Maksimov, Victoria O. Shipunova, Timofei S. Zatsepin, Alexandra N. Bogomazova, Victoria O. Shender, Andrey V. Aralov, Maria A. Lagarkova, Anna M. Varizhuk
Publikováno v:
ACS Sensors. 8:619-629
Autor:
Dmitriy Y. Ryazantsev, Mikhail Yu. Myshkin, Vera A. Alferova, Vladimir B. Tsvetkov, Elena Y. Shustova, Polina N. Kamzeeva, Polina V. Kovalets, Elvira R. Zaitseva, Nadezhda S. Baleeva, Timofei S. Zatsepin, Zakhar O. Shenkarev, Mikhail S. Baranov, Liubov I. Kozlovskaya, Andrey V. Aralov
Publikováno v:
Biomolecules, Vol 11, Iss 10, p 1409 (2021)
Green fluorescent protein (GFP) chromophore and its congeners draw significant attention mostly for bioimaging purposes. In this work we probed these compounds as antiviral agents. We have chosen LTR-III DNA G4, the major G-quadruplex (G4) present in
Externí odkaz:
https://doaj.org/article/eb70196d328044b29c4c485a13dc27cf
Autor:
George V. Shpakovski, Svetlana G. Spivak, Irina N. Berdichevets, Olga G. Babak, Svetlana V. Kubrak, Alexander V. Kilchevsky, Andrey V. Aralov, Ivan Yu. Slovokhotov, Dmitry G. Shpakovski, Ekaterina N. Baranova, Marat R. Khaliluev, Elena K. Shematorova
Publikováno v:
BMC Plant Biology, Vol 17, Iss S1, Pp 1-13 (2017)
Abstract Background The initial stage of the biosynthesis of steroid hormones in animals occurs in the mitochondria of steroidogenic tissues, where cytochrome P450SCC (CYP11A1) encoded by the CYP11A1 gene catalyzes the conversion of cholesterol into
Externí odkaz:
https://doaj.org/article/eab927c9ce47453da599401a1a263815