Zobrazeno 1 - 10
of 503
pro vyhledávání: '"A. Uguzzoni"'
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Adeno-associated viruses 2 (AAV2) are minute viruses renowned for their capacity to infect human cells and akin organisms. They have recently emerged as prominent candidates in the field of gene therapy, primarily attributed to their inheren
Externí odkaz:
https://doaj.org/article/553499d5eb064011adeae295355f32b3
Autor:
Fernandez-de-Cossio-Diaz, Jorge1 (AUTHOR), Uguzzoni, Guido2 (AUTHOR), Ricard, Kévin3 (AUTHOR), Anselmi, Francesca2,4 (AUTHOR), Nizak, Clément5 (AUTHOR) clement.nizak@sorbonne-universite.fr, Pagnani, Andrea2,6,7 (AUTHOR) andrea.pagnani@polito.it, Rivoire, Olivier3,8 (AUTHOR) olivier.rivoire@espci.fr
Publikováno v:
PLoS Computational Biology. 10/14/2024, Vol. 20 Issue 10, p1-13. 13p.
Autor:
Antonio Lorenzon, Lucia Palandri, Francesco Uguzzoni, Catalina Doina Cristofor, Filippo Lozza, Riccardo Poluzzi, Cristiana Rizzi, Pierpaolo Bertoli, Florian Zerzer, Elena Righi
Publikováno v:
International Journal of Public Health, Vol 69 (2024)
Objective: To investigate the effectiveness of SARS-CoV2 vaccination in preventing ordinary or intensive care unit (ICU) admissions and deaths among cases registered during a variant transitional pandemic phase in the geographically and culturally un
Externí odkaz:
https://doaj.org/article/36aeb13bd1054060893f26f2b4e23d26
Publikováno v:
Nature Communications 12, 5800 (2021)
Generative models emerge as promising candidates for novel sequence-data driven approaches to protein design, and for the extraction of structural and functional information about proteins deeply hidden in rapidly growing sequence databases. Here we
Externí odkaz:
http://arxiv.org/abs/2103.03292
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 2, p e1011812 (2024)
The design of proteins with specific tasks is a major challenge in molecular biology with important diagnostic and therapeutic applications. High-throughput screening methods have been developed to systematically evaluate protein activity, but only a
Externí odkaz:
https://doaj.org/article/748fac7a95b3481d9d0044122031bc14
Autor:
Tralli, Giulio, Uguzzoni, Francesco
In this paper we prove a Wiener-type characterization of boundary regularity, in the spirit of a classical result by Landis, for a class of evolutive H\"ormander operators. We actually show the validity of our criterion for a larger class of degenera
Externí odkaz:
http://arxiv.org/abs/1903.04438
Akademický článek
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Autor:
Uguzzoni, Guido, Lovis, Shalini John, Oteri, Francesco, Schug, Alexander, Szurmant, Hendrik, Weigt, Martin
Publikováno v:
Proc. Natl. Acad. Sci. 114, E2662-E2671 (2017)
Proteins have evolved to perform diverse cellular functions, from serving as reaction catalysts to coordinating cellular propagation and development. Frequently, proteins do not exert their full potential as monomers but rather undergo concerted inte
Externí odkaz:
http://arxiv.org/abs/1703.01246
Akademický článek
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Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Deep learning is a powerful tool for the design of novel protein sequences, yet can be computationally very inefficient. Here the authors propose using simple forecasting models to efficiently generate a large number of novel protein structures.
Externí odkaz:
https://doaj.org/article/26264fe401544f27b9d9bdba0ab20a68