Zobrazeno 1 - 10
of 1 349
pro vyhledávání: '"A. Triantos"'
Erdafitinib in Asian patients with advanced solid tumors: an open-label, single-arm, phase IIa trial
Autor:
Joon Oh Park, Yin-Hsun Feng, Wu-Chou Su, Do-Youn Oh, Bhumsuk Keam, Lin Shen, Sang-We Kim, Xiufeng Liu, Huimin Liao, Min Qing, Chong Zhang, Jiaqi Qian, Xiaodan Tang, Peng Li, Spyros Triantos, Hussein Sweiti
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background FGFR genomic aberrations occur in approximately 5–10% of human cancers. Erdafitinib has previously demonstrated efficacy and safety in FGFR-altered advanced solid tumors, such as gliomas, thoracic, gastrointestinal, gynecologica
Externí odkaz:
https://doaj.org/article/46cf37a8f4c5475998d9519b116a314e
Autor:
Aggeletopoulou, Ioanna1 (AUTHOR) iaggel@upatras.gr, Triantos, Christos1 (AUTHOR) chtriantos@upatras.gr
Publikováno v:
International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12395. 20p.
Autor:
Albert Juan Ramon, Chaitanya Parmar, Oscar M. Carrasco-Zevallos, Carlos Csiszer, Stephen S. F. Yip, Patricia Raciti, Nicole L. Stone, Spyros Triantos, Michelle M. Quiroz, Patrick Crowley, Ashita S. Batavia, Joel Greshock, Tommaso Mansi, Kristopher A. Standish
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Accurate identification of genetic alterations in tumors, such as Fibroblast Growth Factor Receptor, is crucial for treating with targeted therapies; however, molecular testing can delay patient care due to the time and tissue required. Succ
Externí odkaz:
https://doaj.org/article/0e8df5bb52f64a9298ae59a4ca11e4d1
Autor:
Hariklia Kranidioti, Konstantinos Zisimopoulos, Theodora Oikonomou, Theodoros Voulgaris, Spyros Siakavellas, Polixeni Agorastou, Melanie Deutsch, Christos Triantos, Ioannis Goulis, George Papatheodoridis, Spilios Manolakopoulos
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Preventing disease progression and viral suppression are the main goals of antiviral therapy in chronic hepatitis B (CHB). Liver stiffness measurement (LSM) by transient elastography is a reliable non-invasive method to assess liv
Externí odkaz:
https://doaj.org/article/1d3ec343a8094c048fa6793a50f91569
Autor:
Suzy Van Sanden, Ayman Youssef, Simona Baculea, Keith Stubbs, Spyros Triantos, Zijiao Yuan, Caitlin Daly
Publikováno v:
Journal of Health Economics and Outcomes Research, Vol 11, Iss 2 (2024)
**Background:** For patients with locally advanced or metastatic urothelial carcinoma (la/mUC), prognosis is poor and effective treatment options are limited. Erdafitinib is an oral fibroblast growth factor receptor (FGFR) kinase inhibitor approved b
Externí odkaz:
https://doaj.org/article/42643995ce534495b7548e8844af371b
Autor:
Konstantinos Papantoniou, Ioanna Aggeletopoulou, Christos Michailides, Ploutarchos Pastras, Christos Triantos
Publikováno v:
Biology, Vol 13, Iss 11, p 945 (2024)
Acute pancreatitis (AP) remains a serious clinical condition, with current treatment options being largely supportive. The discovery of inflammasomes, particularly the NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome, has signi
Externí odkaz:
https://doaj.org/article/ba857b83969247b6a307ba916e69babf
Publikováno v:
Microorganisms, Vol 12, Iss 10, p 2036 (2024)
Irritable bowel syndrome (IBS) is a condition that significantly impacts the lifestyle, health, and habits of numerous individuals worldwide. Its diagnosis and classification are based on the Rome criteria, updated periodically to reflect new researc
Externí odkaz:
https://doaj.org/article/1fccd37bf44b47858e827fffa296a566
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1090 (2024)
Nanotechnology, now established as a transformative technology, has revolutionized medicine by enabling highly targeted drug delivery. The use of organic nanocarriers in drug delivery systems significantly enhances the bioavailability of vitamins and
Externí odkaz:
https://doaj.org/article/f4e00119b06245fc9d0de252cc2c4f57
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1861 (2024)
The human reward network consists of interconnected brain regions that process stimuli associated with satisfaction and modulate pleasure-seeking behaviors. Impairments in reward processing have been implicated in several medical and psychiatric cond
Externí odkaz:
https://doaj.org/article/5e4b350e376447569e7ccf7a5d37b22d
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 252 (2024)
Vitamin D possesses a crucial role in preserving bone health, modulating the immune system responses, and supporting various physiological functions throughout the body. Chronic atrophic autoimmune gastritis (CAAG) constitutes an autoimmune condition
Externí odkaz:
https://doaj.org/article/c874fdedb5564510a5be33bf1984e0ee