Zobrazeno 1 - 10
of 3 338
pro vyhledávání: '"A. T. King"'
Autor:
Daniel C. Scott, Sagar Chittori, Nicholas Purser, Moeko T. King, Samuel A. Maiwald, Kelly Churion, Amanda Nourse, Chan Lee, Joao A. Paulo, Darcie J. Miller, Stephen J. Elledge, J. Wade Harper, Gary Kleiger, Brenda A. Schulman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Specificity of the ubiquitin-proteasome system depends on E3 ligase-substrate interactions. Many such pairings depend on E3 ligases binding to peptide-like sequences - termed N- or C-degrons - at the termini of substrates. However, our knowl
Externí odkaz:
https://doaj.org/article/1085cb553def4be2ba1ef9f68687d295
Autor:
Victor T. King, Wei Lee Chin
Publikováno v:
Southeast Asia, Vol 24, Iss 2, Pp 150-163 (2024)
Purpose – The purpose of this review paper is to investigate the consequences of tourism development and economic growth within the Association of Southeast Asian Nations (ASEAN) countries, focusing specifically on Lao PDR post-pandemic. The advers
Externí odkaz:
https://doaj.org/article/4c2461cb3cb241d7b2e87ede1dd82467
Autor:
Daniel C. Scott, Suresh Dharuman, Elizabeth Griffith, Sergio C. Chai, Jarrid Ronnebaum, Moeko T. King, Rajendra Tangallapally, Chan Lee, Clifford T. Gee, Lei Yang, Yong Li, Victoria C. Loudon, Ha Won Lee, Jason Ochoada, Darcie J. Miller, Thilina Jayasinghe, Joao A. Paulo, Stephen J. Elledge, J. Wade Harper, Taosheng Chen, Richard E. Lee, Brenda A. Schulman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract PROTAC® (proteolysis-targeting chimera) molecules induce proximity between an E3 ligase and protein-of-interest (POI) to target the POI for ubiquitin-mediated degradation. Cooperative E3-PROTAC-POI complexes have potential to achieve neo-su
Externí odkaz:
https://doaj.org/article/6c50c513c918469eaf4c94f0f0e0d58b
Autor:
Yiyin Cao, Haofei Li, Ling Jie Cheng, Madeleine T. King, Georg Kemmler, David Cella, Hongjuan Yu, Weidong Huang, Nan Luo
Publikováno v:
Health Economics Review, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Objective To perform a comparison of the measurement properties of two cancer-specific Multi-Attribute Utility Instruments (MAUIs), EORTC QLU-C10D and FACT-8D, in Chinese patients with hematologic malignancies (HM). Methods We conducted a lo
Externí odkaz:
https://doaj.org/article/22bf55f93dbb42aa8fe3d8c10a568eed
Publikováno v:
Journal of NeuroEngineering and Rehabilitation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Falls due to stumbling are prevalent for transfemoral prosthesis users and may lead to increased injury risk. This preliminary case series analyzes the transfemoral prosthesis user stumble recovery response to highlight key defici
Externí odkaz:
https://doaj.org/article/cc247546d58746aea4cddc358a3a2035
Autor:
Nanthiya Sujijantarat, Kelsey A. Templeton, Joseph P. Antonios, Daniela Renedo, Andrew B. Koo, Joseph O. Haynes, Bushra Fathima, Abdelaziz Amllay, Kamil Nowicki, Anita Huttner, James A. Giles, Dhasakumar Navaratnam, Lauren H. Sansing, Ryan M. Hebert, Joseph T. King, Charles C. Matouk
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 4, Iss 6 (2024)
Background Prior studies have suggested an association between clot histological composition and cause of stroke. However, the results have been conflicting. Our objective is to provide an updated systematic review and meta‐analysis of the associat
Externí odkaz:
https://doaj.org/article/96f3e47c3abb423e9702ff3e6232a091
Macrophage Dvl2 deficiency promotes NOD1-Driven pyroptosis and exacerbates inflammatory liver injury
Autor:
Xiaoye Qu, Dongwei Xu, Tao Yang, Yizhu Tian, Christopher T. King, Xiao Wang, Mingwei Sheng, Yuanbang Lin, Xiyun Bian, Changyong Li, Longfeng Jiang, Qiang Xia, Douglas G. Farmer, Bibo Ke
Publikováno v:
Redox Biology, Vol 79, Iss , Pp 103455- (2025)
Dishevelled 2 (Dvl2) is a key mediator of the Wingless/Wnt signaling pathway that regulates cell proliferation, migration, and immune function. However, little is known about the role of macrophage Dvl2 in modulating NOD1-mediated pyroptosis and hepa
Externí odkaz:
https://doaj.org/article/5c769020c9d04f8282829ed0a437e50c
Autor:
Jiaqi Li, Ari Segel, Xinyang Feng, Jiaxin Cindy Tu, Andy Eck, Kelsey T. King, Babatunde Adeyemo, Nicole R. Karcher, Likai Chen, Adam T. Eggebrecht, Muriah D. Wheelock
Publikováno v:
Harvard Data Science Review, Vol 8, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/8146b2549f78420198b76e3720e1c6c7
Autor:
Daniel Lewis, Ka-Loh Li, Mueez Waqar, David J. Coope, Omar N. Pathmanaban, Andrew T. King, Ibrahim Djoukhadar, Sha Zhao, Timothy F. Cootes, Alan Jackson, Xiaoping Zhu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract A key limitation of current dynamic contrast enhanced (DCE) MRI techniques is the requirement for full-dose gadolinium-based contrast agent (GBCA) administration. The purpose of this feasibility study was to develop and assess a new low GBCA
Externí odkaz:
https://doaj.org/article/7176190d36954bfc8936ef0f28e62558
Autor:
Lene Kongsgaard Nielsen, Fredrik Schjesvold, Sören Möller, Nina Guldbrandsen, Markus Hansson, Kari Remes, Valdas Peceliunas, Niels Abildgaard, Henrik Gregersen, Madeleine T. King
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-18 (2024)
Abstract Background Decisions regarding maintenance therapy in patients with multiple myeloma should be based on both treatment efficacy and health-related quality of life (HRQL) consequences. In the CARFI trial, patients with first relapse of multip
Externí odkaz:
https://doaj.org/article/66aadd268fde4f8ca7e8f753b2c818a7