Zobrazeno 1 - 10
of 117
pro vyhledávání: '"A. T. Hoekstra"'
Autor:
A. Ottria, A. T. Hoekstra, M. Zimmermann, M. van der Kroef, N. Vazirpanah, M. Cossu, E. Chouri, M. Rossato, L. Beretta, R. G. Tieland, C. G. K. Wichers, E. Stigter, C. Gulersonmez, F. Bonte-Mineur, C. R. Berkers, T. R. D. J. Radstake, W. Marut
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Systemic sclerosis (SSc) is a rare chronic disease of unknown pathogenesis characterized by fibrosis of the skin and internal organs, vascular alteration, and dysregulation of the immune system. In order to better understand the immune system and its
Externí odkaz:
https://doaj.org/article/74bc75512ca1480199aa5de734e43fe0
Autor:
Jacob Gerstenberg, Yabo J. Honkpehedji, Jean-Claude Dejon-Agobe, Saidou Mahmoudou, Mario Recker, Romuald Beh Mba, Moustapha Nzamba Maloum, Romeo Laclong Lontchi, Paul A. Nguema Moure, Brice Meulah, Jeannot F. Zinsou, Jean-Ronald Edoa, Bayode R. Adegbite, Michael Ramharter, Bertrand Lell, Selidji T. Agnandji, Peter G. Kremsner, Paul L.A.M. Corstjens, Pytsje T. Hoekstra, Govert J. van Dam, Andrea Kreidenweiss, Ayola A. Adegnika
Publikováno v:
International Journal of Infectious Diseases, Vol 149, Iss , Pp 107253- (2024)
Objectives: Despite evidence of praziquantel's (PZQ) safety for treating schistosomiasis in pregnancy, many countries withhold treatment. Only two randomized controlled trials have investigated PZQ in pregnancy, none involving Schistosoma haematobium
Externí odkaz:
https://doaj.org/article/a8bced0b22984b81aca713d3aef16a3a
Autor:
Pytsje T. Hoekstra, Claudia J. de Dood, Theresia Abdoel, Stan Hilt, Angela van Diepen, Katja Polman, Peter Kremsner, Lisette van Lieshout, Andrea Kreidenweiss, Ayola Akim Adegnika, Daniela Fusco, Tahinamandranto Rasomoelina, Mala Rakoto Andrianarivelo, Raphaël Rakotozandrindrainy, Rivo Andry Rakotoarivelo, Elisa Sicuri, Govert J. van Dam, Paul L. A. M. Corstjens
Publikováno v:
Frontiers in Parasitology, Vol 3 (2024)
BackgroundSchistosomiasis is caused by infection with parasitic Schistosoma worms and affects more than 250 million people globally. The detection of schistosome derived circulating cathodic and anodic antigens (CCA and CAA) has proven highly valuabl
Externí odkaz:
https://doaj.org/article/34c2331594d1400db6aad97ef3f6e922
Autor:
Raphäel Rakotozandrindrainy, Rivo Andry Rakotoarivelo, Irina Kislaya, Valentina Marchese, Tahimandranto Rasamoelina, Jeannine Solonirina, Elveric Fesia Ratiaharison, Ravo Razafindrakoto, Nantenaina Matthieu Razafindralava, Njary Rakotozandrindrainy, Mickael Radomanana, Mala Rakoto Andrianarivelo, Philipp Klein, Eva Lorenz, Anna Jaeger, Pytsje T Hoekstra, Paul L A M Corstjens, Norbert Georg Schwarz, Govert J van Dam, Jürgen May, Daniela Fusco, freeBILy consortium
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 4, p e0011766 (2024)
IntroductionSchistosomiasis is a parasitic infection highly prevalent in sub-Saharan Africa (SSA) with Madagascar being among the countries with highest burden of the disease worldwide. Despite WHO recommendations, suggesting treatment of pregnant wo
Externí odkaz:
https://doaj.org/article/69eab17c35db4546a28615415c7dc3f3
Autor:
Brice Meulah, Prosper Oyibo, Pytsje T Hoekstra, Paul Alvyn Nguema Moure, Moustapha Nzamba Maloum, Romeo Aime Laclong-Lontchi, Yabo Josiane Honkpehedji, Michel Bengtson, Cornelis Hokke, Paul L A M Corstjens, Temitope Agbana, Jan Carel Diehl, Ayola Akim Adegnika, Lisette van Lieshout
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011967 (2024)
IntroductionSchistosomiasis is a significant public health concern, especially in Sub-Saharan Africa. Conventional microscopy is the standard diagnostic method in resource-limited settings, but with limitations, such as the need for expert microscopi
Externí odkaz:
https://doaj.org/article/e17b3f75e97d4b8bb40920adbfaf5867
Autor:
Rens Peeters, Jorge Cuenca-Escalona, Esther A. Zaal, Anna T. Hoekstra, Anouk C. G. Balvert, Marcos Vidal-Manrique, Niek Blomberg, Sjoerd J. van Deventer, Rinke Stienstra, Julia Jellusova, Martin Giera, Luciana Hannibal, Ute Spiekerkoetter, Martin ter Beest, Celia R. Berkers, Annemiek B. van Spriel
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Tetraspanin CD37 deficiency has been reported as a prognostic marker for aggressive B-cell lymphoma. Here, the authors show that CD37 interacts with the fatty acid transporter 1 to inhibit palmitate uptake and its deficiency leads to increased fatty
Externí odkaz:
https://doaj.org/article/06b391ff93194e52ab905cd0ab30f079
Autor:
Daniela Fusco, Raphäel Rakotozandrindrainy, Rivo Andry Rakotoarivelo, Mala Rakoto Andrianarivelo, Njary Rakotozandrindrainy, Tahinamandranto Rasamoelina, Dewi Ismajani Puradiredja, Philipp Klein, Karl Stahlberg, Marie Dechenaud, Eva Lorenz, Anna Jaeger, Andrea Kreidenweiss, Pytsje T. Hoekstra, Akim Ayola Adegnika, Elisa Sicuri, Paul L. A. M. Corstjens, Govert J. van Dam, Jürgen May, Norbert Georg Schwarz, on behalf of the freeBILy consortium
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Mass drug administration (MDA) of praziquantel is one of the main control measures against human schistosomiasis. Although there are claims for including pregnant women, infants and children under the age of 5 years in high-endemi
Externí odkaz:
https://doaj.org/article/639b14698233424bb28438e1ca07d47d
Autor:
Pytsje T Hoekstra, Miriam Casacuberta-Partal, Lisette van Lieshout, Paul L A M Corstjens, Roula Tsonaka, Rufin K Assaré, Kigbafori D Silué, Eliézer K N'Goran, Yves K N'Gbesso, Eric A T Brienen, Meta Roestenberg, Stefanie Knopp, Jürg Utzinger, Jean T Coulibaly, Govert J van Dam
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 12, p e0011008 (2022)
BackgroundMost studies assessing praziquantel (PZQ) efficacy have used relatively insensitive diagnostic methods, thereby overestimating cure rate (CR) and intensity reduction rate (IRR). To determine accurately PZQ efficacy, we employed more sensiti
Externí odkaz:
https://doaj.org/article/61c5aca5f1154848ac29002e2a0b4c79
Autor:
Francesca Tamarozzi, Tamara Ursini, Pytsje T. Hoekstra, Ronaldo Silva, Cecilia Costa, Federico Gobbi, Gerardo B. Monteiro, Leonardo Motta, Govert J. van Dam, Paul L. Corstjens, Lisette van Lieshout, Dora Buonfrate
Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-11 (2021)
Abstract Background An accurate test for the diagnosis and post-treatment follow-up of patients with schistosomiasis is needed. We assessed the performance of different laboratory parameters, including the up-converting reporter particle technology l
Externí odkaz:
https://doaj.org/article/82e37a2a044145be94c4db5676c12675
Autor:
Albert van Dijk, Jennifer Anten, Anne Bakker, Noah Evers, Anna T. Hoekstra, Jung-Chin Chang, Maaike R. Scheenstra, Edwin J. A. Veldhuizen, Mihai G. Netea, Celia R. Berkers, Henk P. Haagsman
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Trained innate immunity can be induced in human macrophages by microbial ligands, but it is unknown if exposure to endogenous alarmins such as cathelicidins can have similar effects. Previously, we demonstrated sustained protection against infection
Externí odkaz:
https://doaj.org/article/d37d6ebc82eb4e7eac6d602f7bf731cf