Zobrazeno 1 - 10
of 114
pro vyhledávání: '"A. T. Hoekstra"'
Autor:
A. Ottria, A. T. Hoekstra, M. Zimmermann, M. van der Kroef, N. Vazirpanah, M. Cossu, E. Chouri, M. Rossato, L. Beretta, R. G. Tieland, C. G. K. Wichers, E. Stigter, C. Gulersonmez, F. Bonte-Mineur, C. R. Berkers, T. R. D. J. Radstake, W. Marut
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Systemic sclerosis (SSc) is a rare chronic disease of unknown pathogenesis characterized by fibrosis of the skin and internal organs, vascular alteration, and dysregulation of the immune system. In order to better understand the immune system and its
Externí odkaz:
https://doaj.org/article/74bc75512ca1480199aa5de734e43fe0
Autor:
Raphäel Rakotozandrindrainy, Rivo Andry Rakotoarivelo, Irina Kislaya, Valentina Marchese, Tahimandranto Rasamoelina, Jeannine Solonirina, Elveric Fesia Ratiaharison, Ravo Razafindrakoto, Nantenaina Matthieu Razafindralava, Njary Rakotozandrindrainy, Mickael Radomanana, Mala Rakoto Andrianarivelo, Philipp Klein, Eva Lorenz, Anna Jaeger, Pytsje T Hoekstra, Paul L A M Corstjens, Norbert Georg Schwarz, Govert J van Dam, Jürgen May, Daniela Fusco, freeBILy consortium
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 4, p e0011766 (2024)
IntroductionSchistosomiasis is a parasitic infection highly prevalent in sub-Saharan Africa (SSA) with Madagascar being among the countries with highest burden of the disease worldwide. Despite WHO recommendations, suggesting treatment of pregnant wo
Externí odkaz:
https://doaj.org/article/69eab17c35db4546a28615415c7dc3f3
Autor:
Brice Meulah, Prosper Oyibo, Pytsje T Hoekstra, Paul Alvyn Nguema Moure, Moustapha Nzamba Maloum, Romeo Aime Laclong-Lontchi, Yabo Josiane Honkpehedji, Michel Bengtson, Cornelis Hokke, Paul L A M Corstjens, Temitope Agbana, Jan Carel Diehl, Ayola Akim Adegnika, Lisette van Lieshout
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011967 (2024)
IntroductionSchistosomiasis is a significant public health concern, especially in Sub-Saharan Africa. Conventional microscopy is the standard diagnostic method in resource-limited settings, but with limitations, such as the need for expert microscopi
Externí odkaz:
https://doaj.org/article/e17b3f75e97d4b8bb40920adbfaf5867
Autor:
Rens Peeters, Jorge Cuenca-Escalona, Esther A. Zaal, Anna T. Hoekstra, Anouk C. G. Balvert, Marcos Vidal-Manrique, Niek Blomberg, Sjoerd J. van Deventer, Rinke Stienstra, Julia Jellusova, Martin Giera, Luciana Hannibal, Ute Spiekerkoetter, Martin ter Beest, Celia R. Berkers, Annemiek B. van Spriel
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Tetraspanin CD37 deficiency has been reported as a prognostic marker for aggressive B-cell lymphoma. Here, the authors show that CD37 interacts with the fatty acid transporter 1 to inhibit palmitate uptake and its deficiency leads to increased fatty
Externí odkaz:
https://doaj.org/article/06b391ff93194e52ab905cd0ab30f079
Autor:
Pytsje T Hoekstra, Miriam Casacuberta-Partal, Lisette van Lieshout, Paul L A M Corstjens, Roula Tsonaka, Rufin K Assaré, Kigbafori D Silué, Eliézer K N'Goran, Yves K N'Gbesso, Eric A T Brienen, Meta Roestenberg, Stefanie Knopp, Jürg Utzinger, Jean T Coulibaly, Govert J van Dam
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 12, p e0011008 (2022)
BackgroundMost studies assessing praziquantel (PZQ) efficacy have used relatively insensitive diagnostic methods, thereby overestimating cure rate (CR) and intensity reduction rate (IRR). To determine accurately PZQ efficacy, we employed more sensiti
Externí odkaz:
https://doaj.org/article/61c5aca5f1154848ac29002e2a0b4c79
Autor:
Yabo Josiane Honkpehedji, Ayôla Akim Adegnika, Jean Claude Dejon-Agobe, Jeannot Fréjus Zinsou, Romuald Beh Mba, Jacob Gerstenberg, Raphaël Rakotozandrindrainy, Rivo Andry Rakotoarivelo, Tahinamandranto Rasamoelina, Elisa Sicuri, Norbert G. Schwarz, Paul L. A. M. Corstjens, Pytsje T. Hoekstra, Govert J. van Dam, Andrea Kreidenweiss, on behalf of the freeBILy Consortium
Publikováno v:
BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Schistosoma antigen detection in urine is a valuable diagnostic approach for schistosomiasis control programmes because of the higher sensitivity compared to parasitological methods and preferred sampling of urine over stool. High
Externí odkaz:
https://doaj.org/article/1c96f41edad241de9bef22e31b15d1e1
Autor:
P. T. Hoekstra, M. Casacuberta Partal, A. S. Amoah, L. van Lieshout, P. L. A. M. Corstjens, S. Tsonaka, R. K. Assaré, K. D. Silué, A. Meité, E. K. N’Goran, Y. K. N’Gbesso, M. Roestenberg, S. Knopp, J. Utzinger, J. T. Coulibaly, G. J. van Dam
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Large scale administration of the anthelminthic drug praziquantel (PZQ) to at-risk populations is the cornerstone of schistosomiasis control, although persisting high prevalence of infections in some areas and growing concerns of
Externí odkaz:
https://doaj.org/article/766b45896c8d465b9ba17a0bfbc67cfe
Publikováno v:
In Contemporary Clinical Trials Communications June 2018 10:80-85
Publikováno v:
Infectious Diseases of Poverty, Vol 6, Iss 1, Pp 1-13 (2017)
Abstract Background Methodological applications of the high sensitivity genus-specific Schistosoma CAA strip test, allowing detection of single worm active infections (ultimate sensitivity), are discussed for efficient utilization in sample pooling s
Externí odkaz:
https://doaj.org/article/5b3aa56c787a41d99f14938d63277204
Autor:
Youthanavanh Vonghachack, Somphou Sayasone, Virak Khieu, Robert Bergquist, Govert J. van Dam, Pytsje T. Hoekstra, Paul L. A. M. Corstjens, Beatrice Nickel, Hanspeter Marti, Jürg Utzinger, Sinuon Muth, Peter Odermatt
Publikováno v:
Infectious Diseases of Poverty, Vol 6, Iss 1, Pp 1-13 (2017)
Abstract Background Given the restricted distribution of Schistosoma mekongi in one province in Lao People’s Democratic Republic (Lao PDR) and two provinces in Cambodia, together with progress of the national control programmes aimed at reducing mo
Externí odkaz:
https://doaj.org/article/7c91ce503eb84135846aa9477fa5c24e