Zobrazeno 1 - 10
of 59
pro vyhledávání: '"A. T. Hesselink"'
Autor:
Kirsten Rozemeijer, Fernando Dias Gonçalves Lima, Timo J. ter Braak, Albertus T. Hesselink, Jan M. Prins, Henry J.C. de Vries, Renske D.M. Steenbergen
Publikováno v:
Tumour Virus Research, Vol 17, Iss , Pp 200275- (2024)
DNA methylation testing on biopsies can detect high-grade anal intraepithelial neoplasia (HGAIN) in need of treatment and anal cancer. This study aimed to analytically validate and determine the diagnostic performance of a newly developed multiplex q
Externí odkaz:
https://doaj.org/article/8337d1365ee844e08848d373b9bcd8b1
Autor:
Lisanne Verhoef, A. N Floore, Saskia Doorn, Kate Cuschieri, Ramya Bhatia, A. T Hesselink, Chris J.L.M. Meijer, Renske D.M. Steenbergen, Daniëlle A.M. Heideman
Publikováno v:
Epigenetics, Vol 17, Iss 10, Pp 1173-1179 (2022)
Sodium bisulphite conversion of DNA to separate methylated from unmethylated cytosines is a standard for methylation analysis. This study evaluated a direct cell conversion protocol on cervical samples as alternative to isolated genomic DNA as input.
Externí odkaz:
https://doaj.org/article/1e33e333d096402e8f72d9240b3b64ad
Autor:
Krishnan Puri Sudhir, Eva Kagenaar, Michelle Meijer, Albertus T. Hesselink, Elisabeth Adams, Katy M. E. Turner, Susie Huntington
Publikováno v:
Diagnostics, Vol 13, Iss 24, p 3612 (2023)
Detecting hypermethylation of tumour suppressor genes could provide an alternative to liquid-based cytology (LBC) triage within HPV primary cervical screening. The impact of using the QIAsure® FAM19A4/mir124-2 DNA Methylation Test (QIAGEN, N.V, Hild
Externí odkaz:
https://doaj.org/article/a0e614b5c3c14ffe9237e21ca1cb13b4
Autor:
Daniëlle A. M. Heideman, Anja Oštrbenk Valenčak, Saskia Doorn, Jesper Bonde, Peter Hillemanns, Grega Gimpelj Domjanič, Jana Mlakar, Albertus T. Hesselink, Chris J. L. M. Meijer, Mario Poljak
Publikováno v:
Viruses, Vol 14, Iss 5, p 893 (2022)
The NeuMoDx HPV assay is a novel fully automated, real-time PCR-based assay for the qualitative detection of high-risk human papillomavirus (HPV) DNA in cervical specimens. The assay specifically identifies HPV16 and HPV18 and concurrently detects 13
Externí odkaz:
https://doaj.org/article/d95a7c88fa8e4fd690ef7b240bcdf492
Autor:
Monika, Hampl, Albertus T, Hesselink, Chris J L M, Meijer, Agnieszka, Denecke, Ina, Einhorn, Axel, Reinecke-Luethge, Carol I, Geppert, Matthias, Jentschke, Karl U, Petry, Peter, Hillemanns
Publikováno v:
International Journal of Cancer, 151(9), 1578-1585. Wiley-Liss Inc.
Members of the German Study Group of Colposcopy (SGK) 2022, ' Evaluation of FAM19A4/miR124-2 methylation performance in the management of CIN3 diagnosed pregnant women ', International Journal of Cancer, vol. 151, no. 9, pp. 1578-1585 . https://doi.org/10.1002/ijc.34153
Members of the German Study Group of Colposcopy (SGK) 2022, ' Evaluation of FAM19A4/miR124-2 methylation performance in the management of CIN3 diagnosed pregnant women ', International Journal of Cancer, vol. 151, no. 9, pp. 1578-1585 . https://doi.org/10.1002/ijc.34153
Pregnant women diagnosed with CIN3 have high regression rates after delivery. Biomarkers are needed to only identify pregnant women with progressive CIN requiring treatment to reduce overreferral and overtreatment. In our study we evaluated the perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c6572a4268a282e47c20640bf6d502
http://www.scopus.com/inward/record.url?scp=85133649282&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85133649282&partnerID=8YFLogxK
Autor:
Frederique J Vink, Chris J L M Meijer, Albertus T Hesselink, Arno N Floore, Birgit I Lissenberg-Witte, Jesper H Bonde, Helle Pedersen, Kate Cuschieri, Ramya Bhatia, Mario Poljak, Anja Oštrbenk Valenčak, Peter Hillemanns, Wim G V Quint, Marta del Pino, Gemma G Kenter, Renske D M Steenbergen, Daniëlle A M Heideman, Maaike C G Bleeker
Publikováno v:
Vink, F J, Meijer, C J L M, Hesselink, A T, Floore, A N, Lissenberg-Witte, B I, Bonde, J H, Pedersen, H, Cuschieri, K, Bhatia, R, Poljak, M, Oštrbenk Valenčak, A, Hillemanns, P, Quint, W G V, del Pino, M, Kenter, G G, Steenbergen, R D M, Heideman, D A M & Bleeker, M C G 2023, ' FAM19A4/miR124-2 Methylation Testing and Human Papillomavirus (HPV) 16/18 Genotyping in HPV-Positive Women Under the Age of 30 Years ', Clinical Infectious Diseases, vol. 76, no. 3, pp. e827-e834 . https://doi.org/10.1093/cid/ciac433, https://doi.org/10.1093/cid/ciac433
Clinical Infectious Diseases, 76(3), e827-e834. Oxford University Press
Clinical Infectious Diseases, 76(3), e827-e834. Oxford University Press
Background High-grade squamous intraepithelial lesions (HSIL) or cervical intraepithelial neoplasia (CIN) grade 2/3 lesions in human papillomavirus (HPV)–positive women Methods A European multicenter retrospective study was designed evaluating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19cf7c0ffc16ad688dd482bb8df3262
https://doi.org/10.1093/cid/ciac433
https://doi.org/10.1093/cid/ciac433
Autor:
Peter J.F. Snijders, Chris J.L.M. Meijer, Johannes Berkhof, Dorien Rijkaart, Renee M. Overmeer, Veerle M.H. Coupé, Renske DM Steenbergen, Daniëlle AM Heideman, Albertus T. Hesselink
Purpose: Screening women for high-grade cervical intraepithelial neoplasia or cervical cancer (CIN3+) by high-risk human papillomavirus (hrHPV) testing has as side-effect the detection of hrHPV-positive women without clinically relevant lesions. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8ce8202f787681ae12a2523f9bb287
https://doi.org/10.1158/1078-0432.c.6519639
https://doi.org/10.1158/1078-0432.c.6519639
Autor:
Peter J.F. Snijders, Chris J.L.M. Meijer, Johannes Berkhof, Dorien Rijkaart, Renee M. Overmeer, Veerle M.H. Coupé, Renske DM Steenbergen, Daniëlle AM Heideman, Albertus T. Hesselink
Supplementary Figures S1-S3; Supplementary Table S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a166f531afbd7db93c2a09fdfa0e6104
https://doi.org/10.1158/1078-0432.22443048.v1
https://doi.org/10.1158/1078-0432.22443048.v1
Autor:
Frederique J Vink, Johannes Berkhof, Helle Pedersen, Jesper Bonde, Peter M. van de Ven, Kate Cuschieri, Saskia Doorn, K. Ulrich Petry, Silvia de Sanjosé, Ditte Møller Ejegod, Chris J.L.M. Meijer, Albertus T. Hesselink, Anja Oštrbenk Valenčak, Wim Quint, Daniëlle A.M. Heideman, Grazyna Stanczuk, Mario Poljak, Arno Floore, Maaike C G Bleeker
Publikováno v:
International Journal of Cancer. 148:396-405
In HPV cervical cancer screening, cytology is used as triage to counter the low specificity of HPV testing. VALID-SCREEN is a EU-multicentre, retrospective study conducted to evaluate the clinical performance of the FAM19A4/miR124-2 methylation-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ed74977cdd8d868bc7bc7ad65b29fe1
https://doi.org/10.1002/ijc.33320
https://doi.org/10.1002/ijc.33320
Autor:
Frederique J, Vink, Chris J L M, Meijer, Albertus T, Hesselink, Arno N, Floore, Birgit I, Lissenberg-Witte, Jesper H, Bonde, Helle, Pedersen, Kate, Cuschieri, Ramya, Bhatia, Mario, Poljak, Anja, Oštrbenk Valenčak, Peter, Hillemanns, Wim G V, Quint, Marta, Del Pino, Gemma G, Kenter, Renske D M, Steenbergen, Daniëlle A M, Heideman, Maaike C G, Bleeker
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
HSIL or CIN2/3 lesions in HPV-positive women30 years have high spontaneous regression rates. To reduce overtreatment, biomarkers are needed to delineate advanced CIN lesions that require treatment. We analysed the FAM19A4/miR124-2 methylation test an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af259777b1063a0a090c3a03feac3ba3
https://pubmed.ncbi.nlm.nih.gov/35686306
https://pubmed.ncbi.nlm.nih.gov/35686306