Zobrazeno 1 - 10
of 41
pro vyhledávání: '"A. T. Cruchley"'
Autor:
Lesley A. Bergmeier, A. T. Cruchley
Publikováno v:
Oral Mucosa in Health and Disease ISBN: 9783319560649
The structure and function of the human oral mucosa have been extensively studied at the level of the constituent tissues and cells over many decades and more recently the molecular biology of this complex biological network has become the subject of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4e11cf10954bb1086eac92cc8a407b1
https://doi.org/10.1007/978-3-319-56065-6_1
https://doi.org/10.1007/978-3-319-56065-6_1
Publikováno v:
Dental Materials. 29:674-681
Objective To investigate the feasibility of iontophoretic delivery of large molecules across buccal mucosa, and to establish its potential for enhanced drug delivery. Methods Qualitative (6 h) and quantitative (8 and 36 h) assessment of porcine bucca
Autor:
Hans-Martin Jäck, Gerald Niedobitek, Maike Buettner, Wolfgang Schuh, A. T. Cruchley, Anke Lang, Birgit Meyer, Paul J. Farrell, Christiane S. Tudor, Mário Henrique M. Barros
Publikováno v:
Journal of General Virology. 93:1059-1064
Epstein–Barr virus (EBV) replicates in superficial differentiated cells of oral hairy leukoplakia (OHL). Differentiation of squamous epithelial cells depends on B-lymphocyte-induced maturation protein 1 (Blimp1). Here we show that expression of the
Autor:
Georgios N. Belibasakis, A. T. Cruchley, Nagihan Bostanci, Michael A. Curtis, Minnie Rangarajan, M. Hamedi
Publikováno v:
Cytokine. 45:99-104
Porphyromonas gingivalis is a major bacterial species implicated in chornic periodontitis, a disease characterized by inflammatory destruction of the tooth supporting tissues. Its main virulence factors are lipopolysaccharide (LPS) and gingipains, a
Autor:
A. T. Cruchley, Eleni Hagi-Pavli, Anura Ariyawardana, Bryan D. Young, Gayani N. Pitiyage, Wanninayake Mudiyanselage Tilakaratne, Ahmad Waseem, Muy-Teck Teh, Farida Fortune, A. Lalli, Tracy Chaplin, J. Stewart
Publikováno v:
Journal of Oral Pathology & Medicine. 37:430-436
BACKGROUND: Oral submucous fibrosis (OSF) is a high-risk pre-cancerous condition where 7‐13% of these patients develop head and neck squamous cell carcinoma (HNSCC). To date there is no cancer predictive markers for OSF patients. Genomic instabilit
Autor:
Caroline Fitchett, Anura Ariyawardana, Farida Fortune, Ahmad Waseem, A. T. Cruchley, Irene M. Leigh, E. Kenneth Parkinson, Muy-Teck Teh, Wanninayake Mudiyanselage Tilakaratne, A. Lalli, Eleni Hagi-Pavli
Publikováno v:
Journal of Oral Pathology & Medicine. 37:211-220
Oral submucous fibrosis (OSF) is characterized by abnormal collagen metabolism in the submucosal connective tissue. Its influence on the overlying epithelium is not known but about 14% of OSF cases undergo malignant transformation to squamous cell ca
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 74
Oral healthcare products are well tolerated and while adverse occurrences are rare there is still a need to explore the interaction between these products and the oral mucosa. This study assessed the effects of oral healthcare ingredients: sodium lau
Autor:
A. T. Cruchley, Carolyn Byrne, Chris Tselepis, Jane E. Hewitt, Alison J. North, Sarah E. Kirk, David R. Garrod, Cord Brakebusch, Martyn A.J. Chidgey, Chris Hail, Reinhard Fässler, Erika Gustafsson, Anita J. Merritt
Publikováno v:
The Journal of Cell Biology
The desmosomal cadherin desmocollin (Dsc)1 is expressed in upper epidermis where strong adhesion is required. To investigate its role in vivo, we have genetically engineered mice with a targeted disruption in the Dsc1 gene. Soon after birth, null mic
Autor:
NM Howie, David M. Williams, Christopher A. Squier, A. T. Cruchley, Philip W. Wertz, TK Trigkas
Publikováno v:
Oral Diseases. 7:349-354
OBJECTIVES:?The aim of this study was to evaluate the effect of short-term exposure to ethanol on the permeability barrier properties of human oral mucosa. MATERIALS AND METHODS:?Permeability constants (Kp× 10?4?cm?min?1) to tritiated water were det
Autor:
Christopher A. Squier, Eleni Hagi-Pavli, Philip W. Wertz, L. Selvaratnam, Irene M. Leigh, David M. Williams, A. T. Cruchley, Harshad Navsaria
Publikováno v:
Oral Diseases. 7:252-258
OBJECTIVES: The aim of this study was to establish whether an in vitro model of human oral mucosa had similar permeability characteristics to normal oral mucosa. Such a model would have considerable value as an alternative to the use of mucosal biops