Zobrazeno 1 - 10
of 465
pro vyhledávání: '"A. Stricker-Krongrad"'
Autor:
Tomoharu Miyashita, Marianna Zahurak, Christine H. Chung, Guy P. Marti, Stephen J. Meltzer, Amir Mehdi Ansari, Aerielle E. Matsangos, Ken Ichi Mukaisho, Marcia Irene Canto, Anne Heloise Stricker-Krongrad, A. Karim Ahmed, Michelle A. Rudek, Maryam Kherad Pezhouh, Ronan J. Kelly, Louis J. Born, Kevan J. Salimian, Frank Lay, Christopher Ng, John W. Harmon
Publikováno v:
Ann Surg
Objective The aim of the study was to investigate whether inhibition of Sonic Hedgehog (SHH) pathway would prevent progression of Barrett's Esophagus (BE) to esophageal adenocarcinoma. Background The hedgehog signaling pathway is a leading candidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1346efc740bd35d48ba9223f82f19d8
https://doi.org/10.1097/sla.0000000000003455
https://doi.org/10.1097/sla.0000000000003455
Autor:
Stricker-Krongrad, Alain1 aastricker@sinclairresearch.com, Shoemake, Catherine1 cshoemake@sinclairresearch.com, Zhong, Miao1 mzhong@sinclairresearch.com, Liu, Jason1 jliu@sinclairresearch.com, Bouchard, Guy1 gbouchard@sinclairresearch.com
Publikováno v:
BMC Clinical Pathology. 1/6/2018, Vol. 17, p1-N.PAG. 6p.
Akademický článek
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Publikováno v:
BMC Clinical Pathology, Vol 18, Iss 1, Pp 1-6 (2018)
BMC Clinical Pathology
BMC Clinical Pathology
Background Measuring expression profiles of inflammatory biomarkers is important in monitoring the polarization of immune responses; therefore, results should be independent of quantitation methods if they are to be accepted as validated clinical pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211379ab0f611a8a4bfafba59e5f45a0
http://link.springer.com/article/10.1186/s12907-017-0068-6
http://link.springer.com/article/10.1186/s12907-017-0068-6
Autor:
Anne Braun, Lilibeth Dofiles, Serge Rousselle, Luis Guerrero, Jane Gunther, Ted Yednock, Alain Stricker-Krongrad, Elizabeth Messersmith
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14314 (2010)
Restenosis remains the main complication of balloon angioplasty and/or stent implantation. Preclinical testing of new pharmacologic agents preventing restenosis largely rely on porcine models, where restenosis is assessed after endothelial abrasion o
Externí odkaz:
https://doaj.org/article/9585ed026af64efea91ac6bcc44868f6
Autor:
Murphy, Steven M., Palmer, Marc, Poole, Michelle Fontilla, Padegimas, Linas, Hunady, Karen, Danzig, Joel, Gill, Sikander, Gill, Rajwant, Ting, Anthony, Sherf, Bruce, Brunden, Kurt, Stricker-Krongrad, Alain
Publikováno v:
In Journal of Pharmacological and Toxicological Methods 2006 54(1):42-55
Autor:
David T. White, Naijia Huang, Jeffrey S. Tan, Kenneth J. Ruterbories, Jason Liu, Derek Brocksmith, Lee J. Burns, Alain Stricker-Krongrad, Nathan Yumibe, Nita J. Patel, Guy Bouchard
Publikováno v:
International Journal of Pharmacokinetics. 2:81-91
Aim: Oral and intravenous pharmacokinetic (PK) studies were conducted in four different minipig strains: Sinclair, Yucatan, Hanford and Göttingen after administration of metformin or R,S-verapamil (R,S-VER). Results: The results indicated that the P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89eb2dfefa3b5798e4b7197e18fc7dc7
https://doi.org/10.4155/ipk-2016-0002
https://doi.org/10.4155/ipk-2016-0002
Autor:
Chris Hanks, Shayne C. Gad, Jason Liu, Amber Fuller, Derek Brocksmith, Miao Zhong, Guy Bouchard, Catherine Shoemake, David T. White, Alain Stricker-Krongrad
Publikováno v:
International Journal of Toxicology. 36:113-123
A functional observational battery (FOB) is recommended as the first-tier neurotoxicity screening in the preclinical safety pharmacology testing guidelines. Minipigs have increasingly been used in regulatory toxicology studies; however, no current FO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb3e174e0286c0be58ff7834fc0e8c3
https://doi.org/10.1177/1091581816686049
https://doi.org/10.1177/1091581816686049
Publikováno v:
Toxicologic Pathology. 44:612-623
The use of the miniature swine as a nonrodent species in research has continued to expand for over a decade, and they are becoming routinely used both in experimental pharmacology and as a therapeutic model for human diseases. Miniature swine models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b53b07ed021c1ea323cc2cae9bfe4e3
https://doi.org/10.1177/0192623316641784
https://doi.org/10.1177/0192623316641784
Autor:
Shayne C. Gad, Marcia E. Pereira, Guy Bouchard, Catherine Shoemake, Alain Stricker-Krongrad, Derek Brocksmith
Publikováno v:
Toxicologic Pathology. 44:421-427
The use of miniature swine as a nonrodent species in safety assessment has continued to expand for over a decade, and they are becoming routinely used in toxicology and in pharmacology as well as a model for human diseases. Miniature swine models are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fe4661931819584f498c954db98bc7
https://doi.org/10.1177/0192623315613337
https://doi.org/10.1177/0192623315613337