Zobrazeno 1 - 10
of 227
pro vyhledávání: '"A. Stavniichuk"'
Independent regulation of Piezo1 activity by principal and intercalated cells of the collecting duct
Autor:
Pyrshev, Kyrylo, Atamanchuk-Stavniichuk, Anna, Kordysh, Mariya, Zaika, Oleg, Tomilin, Viktor N., Pochynyuk, Oleh
Publikováno v:
In Journal of Biological Chemistry January 2024 300(1)
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionRenal fibrosis associated with inflammation is a critical pathophysiological event in chronic kidney disease (CKD). We have developed DM509 which acts concurrently as a farnesoid X receptor agonist and a soluble epoxide hydrolase inhibito
Externí odkaz:
https://doaj.org/article/c9054231921b4a71a8fcd82ce5e01db7
Autor:
Kyrylo Pyrshev, Anna Stavniichuk, Viktor N. Tomilin, Naghmeh Hassanzadeh Khayyat, Guohui Ren, Mariya Kordysh, Oleg Zaika, Mykola Mamenko, Oleh Pochynyuk
Publikováno v:
Physiological Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Abstract Mechanosensitive TRPV4 channel plays a dominant role in maintaining [Ca2+]i homeostasis and flow‐sensitive [Ca2+]i signaling in the renal tubule. Polycystic kidney disease (PKD) manifests as progressive cyst growth due to cAMP‐dependent
Externí odkaz:
https://doaj.org/article/3b29b6251de64c85af74876f3675b2e4
Autor:
Pyrshev, Kyrylo1 (AUTHOR), Stavniichuk, Anna1 (AUTHOR), Tomilin, Viktor N.1 (AUTHOR), Khayyat, Naghmeh Hassanzadeh1 (AUTHOR), Ren, Guohui1 (AUTHOR), Kordysh, Mariya1 (AUTHOR), Zaika, Oleg1 (AUTHOR), Mamenko, Mykola2 (AUTHOR), Pochynyuk, Oleh1 (AUTHOR) oleh.m.pochynyuk@uth.tmc.edu
Publikováno v:
Physiological Reports. Mar2023, Vol. 11 Issue 6, p1-16. 16p.
Autor:
Roman Stavniichuk, Ann DeLaForest, Cayla A. Thompson, James Miller, Rhonda F. Souza, Michele A. Battle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract GATA4 promotes columnar epithelial cell fate during gastric development. When ectopically expressed in the developing mouse forestomach, the tissue emerges as columnar-like rather than stratified squamous with gene expression changes that pa
Externí odkaz:
https://doaj.org/article/4b402ea396e1408f980bb3562bad575b
Autor:
Ann DeLaForest, Bridget M. Kohlnhofer, Olivia D. Franklin, Roman Stavniichuk, Cayla A. Thompson, Kirthi Pulakanti, Sridhar Rao, Michele A. Battle
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1391-1413 (2021)
Background & Aims: The transcription factor GATA4 is broadly expressed in nascent foregut endoderm. As development progresses, GATA4 is lost in the domain giving rise to the stratified squamous epithelium of the esophagus and forestomach (FS), while
Externí odkaz:
https://doaj.org/article/800f3c57a6e441238fb5defc6150fc4d
Akademický článek
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Autor:
Viktor N. Tomilin, Kyrylo Pyrshev, Anna Stavniichuk, Naghmeh Hassanzadeh Khayyat, Guohui Ren, Oleg Zaika, Sherif Khedr, Alexander Staruschenko, Fang C. Mei, Xiaodong Cheng, Oleh Pochynyuk
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Exchange proteins directly activated by cAMP (Epacs) are abundantly expressed in the renal tubules. We used genetic and pharmacological tools in combination with balance, electrophysiological, and biochemical approaches to examine the role of Epac1 a
Externí odkaz:
https://doaj.org/article/c26be524f9554a00be999e91af072896
Autor:
Anna Stavniichuk, Kyrylo Pyrshev, Viktor N. Tomilin, Mariya Kordysh, Oleg Zaika, Oleh Pochynyuk
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 177 (2023)
The renal collecting duct is known to play a critical role in many physiological processes, including systemic water–electrolyte homeostasis, acid–base balance, and the salt sensitivity of blood pressure. ClC-K2 (ClC-Kb in humans) is a Cl−-perm
Externí odkaz:
https://doaj.org/article/908bf37fabd84ce0a2655b415ca31203
Autor:
Stavniichuk, Anna1 (AUTHOR), Pyrshev, Kyrylo1 (AUTHOR), Tomilin, Viktor N.1 (AUTHOR), Kordysh, Mariya1 (AUTHOR), Zaika, Oleg1 (AUTHOR), Pochynyuk, Oleh1 (AUTHOR) oleh.m.pochynyuk@uth.tmc.edu
Publikováno v:
Biomolecules (2218-273X). Jan2023, Vol. 13 Issue 1, p177. 14p.