Zobrazeno 1 - 10
of 3 145
pro vyhledávání: '"A. Soubeyran"'
Autor:
Arnaud Bayle, Laila Belcaid, Sophie Cousin, Kilian Trin, Melissa Alame, Etienne Rouleau, Isabelle Soubeyran, Ludovic Lacroix, Laura Blouin, Damien Vasseur, Amandine Crombe, Simone Mathoulin-Pelissier, Jean-Charles Soria, Carine Bellera, Antoine Italiano
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-5 (2024)
Abstract Selecting patients for phase I cancer trials is crucial to ensure a sufficient life expectancy. Frail patients, better suited for palliative care, should not be exposed to new drugs with minimal benefit. Enrolling patients at high risk of ea
Externí odkaz:
https://doaj.org/article/d05aae3b04e145588413b39998d26d59
Autor:
Sophie Cousin, Jean-Philippe Guégan, Kohei Shitara, Lola Jade Palmieri, Jean Philippe Metges, Simon Pernot, Shota Fukuoka, Shohei Koyama, Hiroyoshi Nishikawa, Carine A. Bellera, Antoine Adenis, Carlos A. Gomez-Roca, Philippe Alexandre Cassier, Antoine Hollebecque, Coralie Cantarel, Michèle Kind, Isabelle Soubeyran, Lucile Vanhersecke, Alban Bessede, Antoine Italiano
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-11 (2024)
Abstract Anti-angiogenic agents elicit considerable immune modulatory effects within the tumor microenvironment, underscoring the rationale for synergistic clinical development of VEGF and immune checkpoint inhibitors in advanced gastric cancer (AGC)
Externí odkaz:
https://doaj.org/article/092395fd8b914e7cbe0ceb717ec9a6b5
Autor:
Marie-Julie Nokin, Alessia Mira, Enrico Patrucco, Biagio Ricciuti, Sophie Cousin, Isabelle Soubeyran, Sonia San José, Serena Peirone, Livia Caizzi, Sandra Vietti Michelina, Aurelien Bourdon, Xinan Wang, Daniel Alvarez-Villanueva, María Martínez-Iniesta, August Vidal, Telmo Rodrigues, Carmen García-Macías, Mark M. Awad, Ernest Nadal, Alberto Villanueva, Antoine Italiano, Matteo Cereda, David Santamaría, Chiara Ambrogio
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Selective KRASG12C inhibitors have been developed to covalently lock the oncogene in the inactive GDP-bound state. Two of these molecules, sotorasib and adagrasib, are approved for the treatment of adult patients with KRASG12C-mutated previo
Externí odkaz:
https://doaj.org/article/720b0c9c9a024f38961f97cf298e776d
Autor:
Bauer, Jürgen M., Pattwell, Megan, Barazzoni, Rocco, Battisti, Nicolò Matteo Luca, Soto-Perez-de-Celis, Enrique, Hamaker, Marije E., Scotté, Florian, Soubeyran, Pierre, Aapro, Matti
Publikováno v:
In European Journal of Cancer September 2024 209
Autor:
Patricia Santofimia-Castaño, Nicolas Fraunhoffer, Xi Liu, Ivan Fernandez Bessone, Marina Pasca di Magliano, Stephane Audebert, Luc Camoin, Matias Estaras, Manon Brenière, Mauro Modesti, Gwen Lomberk, Raul Urrutia, Philippe Soubeyran, Jose Luis Neira, Juan Iovanna
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 475-505 (2024)
Abstract We find that NUPR1, a stress-associated intrinsically disordered protein, induced droplet formation via liquid–liquid phase separation (LLPS). NUPR1-driven LLPS was crucial for the creation of NUPR1-dependent stress granules (SGs) in pancr
Externí odkaz:
https://doaj.org/article/d6378f109e874a1da4c8222d7dc3b37c
Autor:
Arnaud Bayle, Laila Belcaid, Lola-Jade Palmieri, Diego Teysonneau, Sophie Cousin, Mariella Spalato-Ceruso, Mihaela Aldea, Damien Vasseur, Melissa Alame, Laura Blouin, Isabelle Soubeyran, Claudio Nicotra, Maud Ngocamus, Antoine Hollebecque, Yohann Loriot, Benjamin Besse, Ludovic Lacroix, Etienne Rouleau, Fabrice Barlesi, Fabrice Andre, Antoine Italiano
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-7 (2023)
Abstract Background Despite the effectiveness of the various targeted therapies currently approved for solid tumors, acquired resistance remains a persistent problem that limits the ultimate effectiveness of these treatments. Polyclonal resistance to
Externí odkaz:
https://doaj.org/article/52cbb438c71741d8bfa5d463aa3de784
Autor:
P. A. L. Seghers, Shabbir M. H. Alibhai, Nicolò Matteo Luca Battisti, Ravindran Kanesvaran, Martine Extermann, Anita O’Donovan, Sophie Pilleron, Anna Rachelle Mislang, Najia Musolino, Kwok-Leung Cheung, Anthony Staines, Charis Girvalaki, Pierre Soubeyran, Johanneke E. A. Portielje, Siri Rostoft, Marije E. Hamaker, Dominic Trépel, Shane O’Hanlon
Publikováno v:
Global Health Research and Policy, Vol 8, Iss 1, Pp 1-8 (2023)
Abstract Most cancers occur in older people and the burden in this age group is increasing. Over the past two decades the evidence on how best to treat this population has increased rapidly. However, implementation of new best practices has been slow
Externí odkaz:
https://doaj.org/article/c937b0a9ea1845edaec3eb6349dd25d1
Autor:
Hamaker, Marije E., Wildiers, Hans, Ardito, Vittoria, Arsandaux, Julie, Barthod-Malat, Aurore, Davies, Paul, Degol, Lien, Ferrara, Lucia, Fourrier, Celia, Kenis, Cindy, Kret, Marion, Lalet, Caroline, Mathoulin-Pelissier, Simone, O'Hanlon, Shane, Rostoft, Siri, Seghers, Nelleke, Saillour-Glénisson, Florence, Staines, Anthony, Schwimmer, Christine, Thevenet, Vincent, Wallet, Cedric, Soubeyran, Pierre
Publikováno v:
In Journal of Geriatric Oncology May 2024 15(4)
Autor:
Perret, Raul, Charville, Gregory W., Alame, Melissa, Rebier, Flora, Soubeyran, Isabelle, Gross, John M., Graham, Daniel, Green, Donald C., Kerr, Darcy A., Khan, Wahab A., Cloutier, Jeffrey M.
Publikováno v:
In Modern Pathology April 2024 37(4)
Publikováno v:
In Journal of Power Sources 30 March 2024 597