Zobrazeno 1 - 10
of 99
pro vyhledávání: '"A. Snabaitis"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The type 2A protein phosphatase regulatory protein alpha4 (α4) constitutes an anti-apoptotic protein in non-cardiac tissue, however it’s anti-apoptotic properties in the heart are poorly defined. To this end, we knocked down α4 protein e
Externí odkaz:
https://doaj.org/article/f0ba749b7041452ca2c8f5079170e608
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
The type 2A protein phosphatase regulatory protein alpha4 (α4) constitutes an anti-apoptotic protein in non-cardiac tissue, however it’s anti-apoptotic properties in the heart are poorly defined. To this end, we knocked down α4 protein expression
Publikováno v:
Bioorganic & Medicinal Chemistry
Graphical abstract
With the emergence of the third infectious and virulent coronavirus within the past two decades, it has become increasingly important to understand how the virus causes infection. This will inform therapeutic strategies that t
With the emergence of the third infectious and virulent coronavirus within the past two decades, it has become increasingly important to understand how the virus causes infection. This will inform therapeutic strategies that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74004e5d018cb1a0b95f13416c4e6494
https://eprints.kingston.ac.uk/id/eprint/49936/6/Wren-S-49936-AAM.pdf
https://eprints.kingston.ac.uk/id/eprint/49936/6/Wren-S-49936-AAM.pdf
Akademický článek
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Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86234 (2014)
The enzymatic activity of the type 2A protein phosphatase (PP2A) holoenzyme, a major serine/threonine phosphatase in the heart, is conferred by its catalytic subunit (PP2AC). PP2AC activity and subcellular localisation can be regulated by reversible
Externí odkaz:
https://doaj.org/article/deea8de7b77b476a9376fdf694e17ca7
Akademický článek
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Autor:
Michael R. Longman, Asvi Francois, Andrew K. Snabaitis, Michael J. Shattock, Jonathan Cowan, Ali Ryan, Olga Eleftheriadou, Brian E. Wadzinski, Richard J. Heads, Andrii Boguslavskyi
Publikováno v:
Basic Research in Cardiology
Cardiac physiology and hypertrophy are regulated by the phosphorylation status of many proteins, which is partly controlled by a poorly defined type 2A protein phosphatase-alpha4 intracellular signalling axis. Quantitative PCR analysis revealed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275eb352c1b09c3cf51a9bcb2b49be51
https://eprints.kingston.ac.uk/id/eprint/38213/6/Eleftheriadou-O-38213-VoR.pdf
https://eprints.kingston.ac.uk/id/eprint/38213/6/Eleftheriadou-O-38213-VoR.pdf
Autor:
da Silva, R.A.G., Churchward, C.P., Karlyshev, A.V., Eleftheriadou, O., Snabaitis, A.K., Longman, M.R., Ryan, A., Griffin, Ruth
BACKGROUND AND PURPOSE:\ud The level of cell surface expression of the meningococcal vaccine antigen, Factor H binding protein (FHbp) varies between and within strains and this limits the breadth of strains that can be targeted by FHbp-based vaccines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::07a5906c3f6f4a8e4b70781e2bf41de6
https://eprints.kingston.ac.uk/id/eprint/36421/1/Churchward-C-36421-AAM.pdf
https://eprints.kingston.ac.uk/id/eprint/36421/1/Churchward-C-36421-AAM.pdf
Autor:
R A G, da Silva, C P, Churchward, A V, Karlyshev, O, Eleftheriadou, A K, Snabaitis, M R, Longman, A, Ryan, R, Griffin
Publikováno v:
British journal of pharmacology. 174(14)
The level of cell surface expression of the meningococcal vaccine antigen, Factor H binding protein (FHbp) varies between and within strains and this limits the breadth of strains that can be targeted by FHbp-based vaccines. The molecular pathway con
Autor:
Noelia Lezcano, Andrew K. Snabaitis, Cecilia Mundiña-Weilenmann, Metin Avkiran, Alicia Mattiazzi, Martin Vila-Petroff, Carlos Alfredo Valverde, María Ana Cristina Huergo
Publikováno v:
Journal of Molecular and Cellular Cardiology. 49:106-112
article i nfo + /H + exchanger Calcium/calmodulin-dependent protein kinase The Na + /H + exchanger (NHE-1) plays a key role in pHi recovery from acidosis and is regulated by pHi and the ERK1/2-dependent phosphorylation pathway. Since acidosis increas