Zobrazeno 1 - 10
of 5 950
pro vyhledávání: '"A. Skene"'
Nearly fifty years ago, Roberts (1978) postulated that Earth's magnetic field, which is generated by turbulent motions of liquid metal in its outer core, likely results from a subcritical dynamo instability characterised by a dominant balance between
Externí odkaz:
http://arxiv.org/abs/2411.05499
Autor:
Skene, Calum S., Tobias, Steven M.
A weakly nonlinear study is numerically conducted to determine the behaviour near the onset of convection in rotating spherical shells. The mathematical and numerical procedure is described in generality, with the results presented for an Earth-like
Externí odkaz:
http://arxiv.org/abs/2408.15603
Autor:
Meijer, Paul, Howard, Nicole, Liang, Jessica, Kelsey, Autumn, Subramanian, Sathya, Johnson, Ed, Mariz, Paul, Harvey, James, Ambrose, Madeline, Tereshchenko, Vitalii, Beaubien, Aldan, Inala, Neelima, Aggoune, Yousef, Pister, Stark, Vetto, Anne, Kinsey, Melissa, Bumol, Tom, Goldrath, Ananda, Li, Xiaojun, Torgerson, Troy, Skene, Peter, Okada, Lauren, La France, Christian, Thomson, Zach, Graybuck, Lucas
The high incidence of irreproducible research has led to urgent appeals for transparency and equitable practices in open science. For the scientific disciplines that rely on computationally intensive analyses of large data sets, a granular understand
Externí odkaz:
http://arxiv.org/abs/2408.09103
Autor:
Adesola T. Bello, Magali H. Sarafian, Elizabeth A. Wimborne, Benita Middleton, Victoria L. Revell, Florence I. Raynaud, Namrata R. Chowdhury, Daan R. van der Veen, Debra J. Skene, Jonathan R. Swann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Bile acids are trans-genomic molecules arising from the concerted metabolism of the human host and the intestinal microbiota and are important for digestion, energy homeostasis and metabolic regulation. While diurnal variation has been demon
Externí odkaz:
https://doaj.org/article/ce39fe2e71344cf991bc20baa6eb30fb
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Understanding how genetic variants affect the epigenome is key to interpreting GWAS, yet profiling these effects across the non-coding genome remains challenging due to experimental scalability. This necessitates accurate computational model
Externí odkaz:
https://doaj.org/article/017c3affa2604ad582b27a9346c01e5f
Autor:
Ciro della Monica, Victoria Revell, Giuseppe Atzori, Rhiannon Laban, Simon S. Skene, Amanda Heslegrave, Hana Hassanin, Ramin Nilforooshan, Henrik Zetterberg, Derk-Jan Dijk
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Plasma biomarkers of dementia, including phosphorylated tau (p-tau217), offer promise as tools for diagnosis, stratification for clinical trials, monitoring disease progression, and assessing the success of interventions in those living with
Externí odkaz:
https://doaj.org/article/b7a19a55d5b447cca927ff0807044a82
Autor:
Manuel Spitschan, Grégory Hammad, Christine Blume, Christina Schmidt, Debra J. Skene, Katharina Wulff, Nayantara Santhi, Johannes Zauner, Mirjam Münch
Publikováno v:
BMC Digital Health, Vol 2, Iss 1, Pp 1-10 (2024)
Abstract Background Light exposure significantly impacts human health, regulating our circadian clock, sleep–wake cycle and other physiological processes. With the emergence of wearable light loggers and dosimeters, research on real-world light exp
Externí odkaz:
https://doaj.org/article/544d527480154a19a1c545dc3b39b7c3
Autor:
Samir Rachid Zaim, Mark-Phillip Pebworth, Imran McGrath, Lauren Okada, Morgan Weiss, Julian Reading, Julie L. Czartoski, Troy R. Torgerson, M. Juliana McElrath, Thomas F. Bumol, Peter J. Skene, Xiao-jun Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Single-cell assay for transposase-accessible chromatin using sequencing (scATAC-seq) is being increasingly used to study gene regulation. However, major analytical gaps limit its utility in studying gene regulatory programs in complex diseas
Externí odkaz:
https://doaj.org/article/510a659dc6a34101b8936defcaa98168
Autor:
Lisa McCann, Liane Lewis, Olubukola Oduntan, Jenny Harris, Andrew Darley, Geir V Berg, Simone Lubowitzki, Katy Cheevers, Morven Miller, Jo Armes, Emma Ream, Patricia Fox, Eileen Patricia Furlong, Alexander Gaiger, Grigorios Kotronoulas, Elisabeth Patiraki, Stylianos Katsaragakis, Paul McCrone, Christine Miaskowski, Antonella Cardone, Dawn Orr, Adrian Flowerday, Simon Skene, Margaret Moore, Nicosha De Souza, Peter Donnan, Roma Maguire
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e53834 (2024)
BackgroundPatients receiving chemotherapy require ongoing symptom monitoring and management to optimize their outcomes. In recent years, digital remote monitoring interventions have emerged to provide enhanced cancer care delivery experiences to pati
Externí odkaz:
https://doaj.org/article/745a21225592462eb59847b3e5397fa2
Many physical questions in fluid dynamics can be recast in terms of norm constrained optimisation problems; which in-turn, can be further recast as unconstrained problems on spherical manifolds. Due to the nonlinearities of the governing PDEs, and th
Externí odkaz:
http://arxiv.org/abs/2210.17194