Zobrazeno 1 - 10
of 167
pro vyhledávání: '"A. Senabouth"'
Autor:
Drew Neavin, Anne Senabouth, Himanshi Arora, Jimmy Tsz Hang Lee, Aida Ripoll-Cladellas, sc-eQTLGen Consortium, Lude Franke, Shyam Prabhakar, Chun Jimmie Ye, Davis J. McCarthy, Marta Melé, Martin Hemberg, Joseph E. Powell
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-24 (2024)
Abstract Recent innovations in single-cell RNA-sequencing (scRNA-seq) provide the technology to investigate biological questions at cellular resolution. Pooling cells from multiple individuals has become a common strategy, and droplets can subsequent
Externí odkaz:
https://doaj.org/article/7209fadf8e984cfb87325f01f83f0d88
Autor:
Anne Senabouth, Maciej Daniszewski, Grace E. Lidgerwood, Helena H. Liang, Damián Hernández, Mehdi Mirzaei, Stacey N. Keenan, Ran Zhang, Xikun Han, Drew Neavin, Louise Rooney, Maria Isabel G. Lopez Sanchez, Lerna Gulluyan, Joao A. Paulo, Linda Clarke, Lisa S. Kearns, Vikkitharan Gnanasambandapillai, Chia-Ling Chan, Uyen Nguyen, Angela M. Steinmann, Rachael A. McCloy, Nona Farbehi, Vivek K. Gupta, David A. Mackey, Guy Bylsma, Nitin Verma, Stuart MacGregor, Matthew J. Watt, Robyn H. Guymer, Joseph E. Powell, Alex W. Hewitt, Alice Pébay
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Age-related macular degeneration (AMD) is a leading cause of vision loss, and there is no approved treatment for AMD with geographic atrophy. Here, the authors used transcriptomic and proteomic analyses of patient induced pluripotent stem cell-derive
Externí odkaz:
https://doaj.org/article/26ee70153c844e808b5ef6d67e2ac7a9
Autor:
Daniszewski, Maciej, Senabouth, Anne, Liang, Helena H., Han, Xikun, Lidgerwood, Grace E., Hernández, Damián, Sivakumaran, Priyadharshini, Clarke, Jordan E., Lim, Shiang Y., Lees, Jarmon G., Rooney, Louise, Gulluyan, Lerna, Souzeau, Emmanuelle, Graham, Stuart L., Chan, Chia-Ling, Nguyen, Uyen, Farbehi, Nona, Gnanasambandapillai, Vikkitharan, McCloy, Rachael A., Clarke, Linda, Kearns, Lisa S., Mackey, David A., Craig, Jamie E., MacGregor, Stuart, Powell, Joseph E., Pébay, Alice, Hewitt, Alex W.
Publikováno v:
In Cell Genomics 8 June 2022 2(6)
Akademický článek
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Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time
Autor:
Lidgerwood, Grace E., Senabouth, Anne, Smith-Anttila, Casey J.A., Gnanasambandapillai, Vikkitharan, Kaczorowski, Dominik C., Amann-Zalcenstein, Daniela, Fletcher, Erica L., Naik, Shalin H., Hewitt, Alex W., Powell, Joseph E., Pébay, Alice
Publikováno v:
In Genomics, Proteomics & Bioinformatics April 2021 19(2):223-242
Transcriptomic Profiling of Human Pluripotent Stem Cell-derived Retinal Pigment Epithelium over Time
Autor:
Grace E. Lidgerwood, Anne Senabouth, Casey J.A. Smith-Anttila, Vikkitharan Gnanasambandapillai, Dominik C. Kaczorowski, Daniela Amann-Zalcenstein, Erica L. Fletcher, Shalin H. Naik, Alex W. Hewitt, Joseph E. Powell, Alice Pébay
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 19, Iss 2, Pp 223-242 (2021)
Human pluripotent stem cell (hPSC)-derived progenies are immature versions of cells, presenting a potential limitation to the accurate modelling of diseases associated with maturity or age. Hence, it is important to characterise how closely cells use
Externí odkaz:
https://doaj.org/article/a1b752ada11e4c119fcf167e7656b297
Autor:
Drew Neavin, Quan Nguyen, Maciej S. Daniszewski, Helena H. Liang, Han Sheng Chiu, Yong Kiat Wee, Anne Senabouth, Samuel W. Lukowski, Duncan E. Crombie, Grace E. Lidgerwood, Damián Hernández, James C. Vickers, Anthony L. Cook, Nathan J. Palpant, Alice Pébay, Alex W. Hewitt, Joseph E. Powell
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-19 (2021)
Abstract Background The discovery that somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) has provided a foundation for in vitro human disease modelling, drug development and population genetics studies. Gene expression plays
Externí odkaz:
https://doaj.org/article/d89867322e804dd0acd2dc0180fe5fe8
Autor:
Maciej Daniszewski, Anne Senabouth, Helena H. Liang, Xikun Han, Grace E. Lidgerwood, Damián Hernández, Priyadharshini Sivakumaran, Jordan E. Clarke, Shiang Y. Lim, Jarmon G. Lees, Louise Rooney, Lerna Gulluyan, Emmanuelle Souzeau, Stuart L. Graham, Chia-Ling Chan, Uyen Nguyen, Nona Farbehi, Vikkitharan Gnanasambandapillai, Rachael A. McCloy, Linda Clarke, Lisa S. Kearns, David A. Mackey, Jamie E. Craig, Stuart MacGregor, Joseph E. Powell, Alice Pébay, Alex W. Hewitt
Publikováno v:
Cell Genomics, Vol 2, Iss 6, Pp 100142- (2022)
Summary: To assess the transcriptomic profile of disease-specific cell populations, fibroblasts from patients with primary open-angle glaucoma (POAG) were reprogrammed into induced pluripotent stem cells (iPSCs) before being differentiated into retin
Externí odkaz:
https://doaj.org/article/bda5107c7c8a45e0aa69bcd697f93428
Akademický článek
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Autor:
Hannah Currant, Pirro Hysi, Tomas W. Fitzgerald, Puya Gharahkhani, Pieter W. M. Bonnemaijer, Anne Senabouth, Alex W. Hewitt, UK Biobank Eye and Vision Consortium, International Glaucoma Genetics Consortium, Denize Atan, Tin Aung, Jason Charng, Hélène Choquet, Jamie Craig, Peng T. Khaw, Caroline C. W. Klaver, Michiaki Kubo, Jue-Sheng Ong, Louis R. Pasquale, Charles A. Reisman, Maciej Daniszewski, Joseph E. Powell, Alice Pébay, Mark J. Simcoe, Alberta A. H. J. Thiadens, Cornelia M. van Duijn, Seyhan Yazar, Eric Jorgenson, Stuart MacGregor, Chris J. Hammond, David A. Mackey, Janey L. Wiggs, Paul J. Foster, Praveen J. Patel, Ewan Birney, Anthony P. Khawaja
Publikováno v:
PLoS Genetics, Vol 17, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/64abaab7be3d461887d9446f188a5fb2