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pro vyhledávání: '"A. Segelle"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Chromatin is known to regulate splicing by modulating recruitment of splicing factors. Using machine learning approaches, the authors have underlined a chromatin code for alternative splicing regulation that is conserved amongst cell lines.
Externí odkaz:
https://doaj.org/article/a2974370e88e459b9526094b9f6797a2
Publikováno v:
Revue de l'infirmiere. 71(278)
A major public health problem, polytrauma is the leading cause of death in the 15-35 age group, 50% of which occurs within the first hour. This is why the initial care of these patients and their rapid referral to a specialized center (trauma center)
Akademický článek
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Autor:
Bilal Al Jaam, Katy Heu, Florian Pennarubia, Alexandre Segelle, Laetitia Magnol, Agnès Germot, Sébastien Legardinier, Véronique Blanquet, Abderrahman Maftah
Publikováno v:
Open Biology, Vol 6, Iss 9 (2016)
Postnatal skeletal muscle growth results from the activation of satellite cells and/or an increase in protein synthesis. The Notch signalling pathway maintains satellite cells in a quiescent state, and once activated, sustains their proliferation and
Externí odkaz:
https://doaj.org/article/cdc4148c16b049a7b99a710198f15a29
Publikováno v:
La Revue de l'Infirmière. 71:53-54
Autor:
Reini F. Luco, A. Segelle, Núñez-Álvarez Y, Andrew J. Oldfield, Kimberly M. Webb, Philipp Voigt
Cell differentiation and reprogramming depend on coordinated changes in specific alternative splicing events. How these cell type-specific splicing patterns are dynamically modified in response to a stimulus remains elusive. Taking advantage of the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66166368828ad22063c0dd337f6f54a3
https://doi.org/10.1101/2021.05.04.442453
https://doi.org/10.1101/2021.05.04.442453
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12, pp.682. ⟨10.1038/s41467-021-20979-x⟩
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Nature Publishing Group, 2021, 12, pp.682. ⟨10.1038/s41467-021-20979-x⟩
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Alternative splicing relies on the combinatorial recruitment of splicing regulators to specific RNA binding sites. Chromatin has been shown to impact this recruitment. However, a limited number of histone marks have been studied at a global level. In
Autor:
Alexandre Segelle, Yaiza Nuñez-Alvarez, Andrew J. Oldfield, Kimberly M. Webb, Philipp Voigt, Reini F. Luco
Publikováno v:
Segelle, A, Núñez-Álvarez, Y, Oldfield, A J, Webb, K M, Voigt, P & Luco, R F 2022, ' Histone marks regulate the epithelial-to-mesenchymal transition via alternative splicing ', Cell Reports, vol. 38, no. 7, 110357 . https://doi.org/10.1016/j.celrep.2022.110357
Histone modifications have long been shown to impact final splicing decisions via modulation of RNA polymerase II elongation rate and/or recruitment of the splicing regulators to their RNA binding sites. However there is little evidence of the drivin
Autor:
Segelle, Alexandre
Publikováno v:
Agricultural sciences. Université Montpellier, 2020. English. ⟨NNT : 2020MONTT017⟩
Alternative splicing is a key mechanism for cell identity that increases the protein diversity and plasticity of a limited coding genome. Disease-specific splice variants are more and more identified, and splicing-targeting strategies are turning int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2592::1307e517edf1a71ada19f13cd256ac09
https://tel.archives-ouvertes.fr/tel-03137009/document
https://tel.archives-ouvertes.fr/tel-03137009/document
Akademický článek
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