Zobrazeno 1 - 10
of 644
pro vyhledávání: '"A. Schlunck"'
Autor:
Stefaniya K. Boneva, Julian Wolf, Malte Jung, Gabriele Prinz, Toco Y. P. Chui, Jacqueline Jauch, Anne Drougard, J. Andrew Pospisilik, Anja Schlecht, Felicitas Bucher, Richard B. Rosen, Hansjürgen Agostini, Günther Schlunck, Clemens A. K. Lange
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Background Despite great advances in proliferative diabetic retinopathy (PDR) therapy over the last decades, one third of treated patients continue to lose vision. While resident vitreous macrophages called hyalocytes have been implicated in
Externí odkaz:
https://doaj.org/article/827468ebd85945bda91aa82c724d8c7e
Autor:
Paula Liang, Jan Ness, Julian Rapp, Stefaniya Boneva, Melanie Schwämmle, Malte Jung, Günther Schlunck, Hansjürgen Agostini, Felicitas Bucher
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background The IL-6 cytokine family, with its crucial and pleiotropic intracellular signaling pathway STAT3, is a promising target for treating vasoproliferative retinal diseases. Previous research has shown that IL-6 cis-signaling (via memb
Externí odkaz:
https://doaj.org/article/7cb48b4b0707425787674009e469b030
Genotyping single point mutations in rd1 and rd8 mice using melting curve analysis of qPCR fragments
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract PCR is tolerant to single nucleotide mismatches. Therefore, genotyping of point mutations by PCR requires special conditions for the amplification of allele-specific PCR fragments. MS-PCR (mutagenically separated PCR) is an improved version
Externí odkaz:
https://doaj.org/article/7f5088d57eff44bcbd82ac0d94c6c0fa
Autor:
Lasse Wolfram, Clara Gimpel, Melanie Schwämmle, Simon J. Clark, Daniel Böhringer, Günther Schlunck
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Alterations in the structure and composition of Bruch’s membrane (BrM) and loss of retinal pigment epithelial (RPE) cells are associated with various ocular diseases, notably age-related macular degeneration (AMD) as well as several inheri
Externí odkaz:
https://doaj.org/article/423932a85ad744eea94258f544c5be04
Autor:
Rapp, Julian, Ness, Jan, Wolf, Julian, Hospach, Alban, Liang, Paula, Hug, Martin J., Agostini, Hansjürgen, Schlunck, Günther, Lange, Clemens, Bucher, Felicitas
Publikováno v:
In BBA - Molecular Basis of Disease March 2024 1870(3)
Autor:
Schlunck, Günther1 (AUTHOR) guenther.schlunck@uniklinik-freiburg.de, Maier, Philip1 (AUTHOR) philip.maier@uniklinik-freiburg.de, Maier, Barbara2 (AUTHOR) barbara.maier@uniklinik-freiburg.de, Maier, Wolfgang3 (AUTHOR) maierw@informatik.uni-freiburg.de, Strempel, Sebastian4 (AUTHOR) sebastian.strempel@microsynth.ch, Reinhard, Thomas1 (AUTHOR) thomas.reinhard@uniklinik-freiburg.de, Heinzelmann, Sonja1 (AUTHOR) sonja.heinzelmann@uniklinik-freiburg.de
Publikováno v:
International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p6128. 8p.
Autor:
Thabo Lapp, Paola Kammrath Betancor, Günther Schlunck, Claudia Auw-Hädrich, Philip Maier, Clemens Lange, Thomas Reinhard, Julian Wolf
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2024)
PurposeCorneal infections are a leading cause of visual impairment and blindness worldwide. Here we applied high-resolution transcriptomic profiling to assess the general and pathogen-specific molecular and cellular mechanisms during human corneal in
Externí odkaz:
https://doaj.org/article/9396f92041314fce8d077b0a78606850
Akademický článek
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Autor:
Sebastian Kistenmacher, Melanie Schwämmle, Gottfried Martin, Eva Ulrich, Stefan Tholen, Oliver Schilling, Andreas Gießl, Ursula Schlötzer-Schrehardt, Felicitas Bucher, Günther Schlunck, Irina Nazarenko, Thomas Reinhard, Naresh Polisetti
Publikováno v:
Cells, Vol 13, Iss 7, p 623 (2024)
Limbal epithelial progenitor cells (LEPC) rely on their niche environment for proper functionality and self-renewal. While extracellular vesicles (EV), specifically small EVs (sEV), have been proposed to support LEPC homeostasis, data on sEV derived
Externí odkaz:
https://doaj.org/article/cd3bcdc523f747d3bd412ebb516efc7d
Akademický článek
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