Zobrazeno 1 - 10
of 80
pro vyhledávání: '"A. Sampath Narayanan"'
Autor:
Sampath Narayanan, PhD, Samuel Röhl, MD, PhD, Mariette Lengquist, BS, Malin Kronqvist, MS, Ljubica Matic, PhD, Anton Razuvaev, MD, PhD
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100111- (2023)
Objective: Atherosclerosis is a leading cause of mortality in the rapidly growing population with diabetes mellitus. Vascular interventions in patients with diabetes can lead to complications attributed to defective vascular remodeling and impaired h
Externí odkaz:
https://doaj.org/article/a66b2f3ffcf2488782b930c66f26de5b
Autor:
Sampath Narayanan, Sofie Eliasson Angelstig, Cheng Xu, Jacob Grünler, Allan Zhao, Wan Zhu, Ning Xu Landén, Mona Ståhle, Jingping Zhang, Mircea Ivan, Raluca Georgiana Maltesen, Ileana Ruxandra Botusan, Neda Rajamand Ekberg, Xiaowei Zheng, Sergiu-Bogdan Catrina
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Narayanan et al. show that local administration of miR-210 accelerates wound healing specifically in diabetic mice. They find that miR-210 restores the metabolic balance in diabetic wounds by activating glycolysis and cellular migration. This study p
Externí odkaz:
https://doaj.org/article/80812abc7eff46a8a33277442fd73105
Autor:
Katarina Wadén, Eva Karlöf, Sampath Narayanan, Mariette Lengquist, Göran K. Hansson, Ulf Hedin, Joy Roy, Ljubica Matic
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104219- (2022)
Summary: Unstable carotid stenosis is an important cause of ischemic stroke, yet the basis of disease pathophysiology remains largely unknown. We hypothesized that integrated analyses of symptomatic carotid stenosis patients at increased stroke risk
Externí odkaz:
https://doaj.org/article/8307a2ba29fc4cb3a9474a704d3de232
Autor:
Xiaowei Zheng, Sampath Narayanan, Cheng Xu, Sofie Eliasson Angelstig, Jacob Grünler, Allan Zhao, Alessandro Di Toro, Luciano Bernardi, Massimiliano Mazzone, Peter Carmeliet, Marianna Del Sole, Giancarlo Solaini, Elisabete A Forsberg, Ao Zhang, Kerstin Brismar, Tomas A Schiffer, Neda Rajamand Ekberg, Ileana Ruxandra Botusan, Fredrik Palm, Sergiu-Bogdan Catrina
Publikováno v:
eLife, Vol 11 (2022)
Background: Excessive production of mitochondrial reactive oxygen species (ROS) is a central mechanism for the development of diabetes complications. Recently, hypoxia has been identified to play an additional pathogenic role in diabetes. In this stu
Externí odkaz:
https://doaj.org/article/de99ad9d49774afc98f983792fb23b0a
Autor:
Sampath Narayanan, Sofija Vuckovic, Robert Wirka, Mariette Lengquist, Thomas Quertermous, Ulf Hedin, Ljubica Matic
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 413- (2022)
Externí odkaz:
https://doaj.org/article/cb0ec5b5acf0475f9f86f51bc559c879
Autor:
Ileana Ruxandra Botusan, Xiaowei Zheng, Sampath Narayanan, Jacob Grünler, Vivekananda Gupta Sunkari, Freja S Calissendorff, Ishrath Ansurudeen, Christopher Illies, Johan Svensson, John-Olov Jansson, Claes Ohlsson, Kerstin Brismar, Sergiu-Bogdan Catrina
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193084 (2018)
IGF-I is a growth factor, which is expressed in virtually all tissues. The circulating IGF-I is however derived mainly from the liver. IGF-I promotes wound healing and its levels are decreased in wounds with low regenerative potential such as diabeti
Externí odkaz:
https://doaj.org/article/83a6106a8a804315ba7eca12fde511d5
Autor:
Sampath Narayanan, Sofija Vuckovic, Robert Wirka, Mariette Lengquist, Thomas Quertermous, Ulf Hedin, Ljubica Matic
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background and Aim: A central role of vascular smooth muscle cells (SMCs) in atherosclerosis has recently evolved that suggests causal genetic links to disease processes. Single cell sequencing studies of atherosclerotic plaques have identified multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::666fcb660dca204be62f11c1dcf82b98
https://doi.org/10.1161/atvb.42.suppl_1.218
https://doi.org/10.1161/atvb.42.suppl_1.218
Autor:
Cheng Xu, Sampath Narayanan, Xiaowei Zheng, Sofie Eliasson Angelstig, Jacob Grünler, Allan Zhao, Alessandro Di Toro, Luciano Bernardi, Massimiliano Mazzone, Peter Carmeliet, Marianna Del Sole, Giancarlo Solaini, Elisabete A Forsberg, Ao Zhang, Kerstin Brismar, Tomas A Schiffer, Neda Rajamand Ekberg, Ileana Ruxandra Botusan, Fredrik Palm, Sergiu-Bogdan Catrina
Publikováno v:
eLife, Vol 11 (2022)
Background:Excessive production of mitochondrial reactive oxygen species (ROS) is a central mechanism for the development of diabetes complications. Recently, hypoxia has been identified to play an additional pathogenic role in diabetes. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba987cf0007823495f417006e15b9273
https://elifesciences.org/articles/70714
https://elifesciences.org/articles/70714
Autor:
Cheng Xu, Sampath Narayanan, Xiaowei Zheng, Sofie Eliasson Angelstig, Jacob Grünler, Allan Zhao, Alessandro Di Toro, Luciano Bernardi, Massimiliano Mazzone, Peter Carmeliet, Marianna Del Sole, Giancarlo Solaini, Elisabete A Forsberg, Ao Zhang, Kerstin Brismar, Tomas A Schiffer, Neda Rajamand Ekberg, Ileana Ruxandra Botusan, Fredrik Palm, Sergiu-Bogdan Catrina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df8c381aa5281baf60deedb3bb87974f
https://doi.org/10.7554/elife.70714.sa2
https://doi.org/10.7554/elife.70714.sa2
Autor:
John Pernow, Till Seime, Jiangning Yang, Ekaterina Chernogubova, Xiaowei Zheng, Sergiu-Bogdan Catrina, Ali Mahdi, Aida Collado, Yahor Tratsiakovich, Lars Maegdefessel, Ulf Hedin, Michael Alvarsson, Tong Jiao, Sampath Narayanan, Hong Jin, Changyan Sun, Hanna Winter, Zhichao Zhou
Red blood cells (RBCs) act as mediators of vascular injury in type 2 diabetes mellitus (T2DM). miR-210 plays a protective role in cardiovascular homeostasis and is decreased in whole blood of T2DM mice. We hypothesized that downregulation of RBC miR-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c0c73a87d79c7770ad52cd7bec1d92
https://doi.org/10.2337/figshare.16896523
https://doi.org/10.2337/figshare.16896523