Zobrazeno 1 - 10
of 189
pro vyhledávání: '"A. Sachslehner"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The mammalian epidermis has evolved to protect the body in a dry environment. Genes of the epidermal differentiation complex (EDC), such as FLG (filaggrin), are implicated in the barrier function of the epidermis. Here, we investigated the m
Externí odkaz:
https://doaj.org/article/6854616ed14e400089174d616d70b207
Publikováno v:
In Developmental Biology November 2024 515:60-66
Autor:
Marjolein Carron, Attila Placido Sachslehner, Munevver Burcu Cicekdal, Inge Bruggeman, Suzan Demuynck, Bahar Golabi, Elfride De Baere, Wim Declercq, Erwin Tschachler, Kris Vleminckx, Leopold Eckhart
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Cornified skin appendages, such as hair and nails, are major evolutionary innovations of terrestrial vertebrates. Human hair and nails consist largely of special intermediate filament proteins, known as hair keratins, which are expressed und
Externí odkaz:
https://doaj.org/article/a710d9a58fc84d2b8c16e5cff7cd038f
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The function of the skin as a barrier against the environment depends on the differentiation of epidermal keratinocytes into highly resilient corneocytes that form the outermost skin layer. Many genes encoding structural components of corneo
Externí odkaz:
https://doaj.org/article/609fdac880b5413da327ee0db538da56
Autor:
Marta Surbek, Tessa Van de Steene, Attila Placido Sachslehner, Bahar Golabi, Johannes Griss, Sven Eyckerman, Kris Gevaert, Leopold Eckhart
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Transglutaminase 1 (TGM1) plays an essential role in skin barrier formation by cross-linking proteins in differentiated keratinocytes. Here, we established a protocol for the antibody-dependent detection of TGM1 protein and the parallel dete
Externí odkaz:
https://doaj.org/article/e17a93f2ae7644e1888d6ca051394575
Autor:
Steinbinder, Julia1 (AUTHOR), Sachslehner, Attila Placido1 (AUTHOR), Holthaus, Karin Brigit1 (AUTHOR), Eckhart, Leopold1 (AUTHOR) leopold.eckhart@meduniwien.ac.at
Publikováno v:
Scientific Reports. 4/23/2024, Vol. 14 Issue 1, p1-11. 11p.
Autor:
Steinbinder, Julia1 (AUTHOR), Sachslehner, Attila Placido1 (AUTHOR), Holthaus, Karin Brigit1 (AUTHOR), Eckhart, Leopold1 (AUTHOR) leopold.eckhart@meduniwien.ac.at
Publikováno v:
Scientific Reports. 1/16/2024, Vol. 14 Issue 1, p1-12. 12p.
Akademický článek
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Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The epidermal differentiation complex (EDC) is a cluster of genes encoding components of the skin barrier in terrestrial vertebrates. EDC genes can be categorized as S100 fused-type protein (SFTP) genes such as filaggrin, which contain two c
Externí odkaz:
https://doaj.org/article/04914df8726c435bb6c5e3acae252f27
Akademický článek
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