Zobrazeno 1 - 10
of 10
pro vyhledávání: '"A. S.M. Iskander"'
CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma
Autor:
Roxan Ara, Mohammad H. Rashid, Iryna Lebedyeva, Ping Chang Lin, Ali S. Arbab, Thaiz F. Borin, Bhagelu R. Achyut, Roni J. Bollag, Kartik Angara, A. S.M. Iskander
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 10, Pp 1070-1082 (2018)
BACKGROUND: Glioblastoma (GBM) was shown to relapse faster and displayed therapeutic resistance to antiangiogenic therapies (AATs) through an alternative tumor cell-driven mechanism of neovascularization called vascular mimicry (VM). We identified hi
Autor:
Bhagelu R. Achyut, Robert A. Knight, Ali S. Arbab, Alfonso G. Scicli, Roxan Ara, Adarsh Shankar, A. S.M. Iskander
Publikováno v:
Cancer Biology & Therapy. 17:280-290
Bone marrow derived cells (BMDCs) have been shown to contribute in the tumor development. In vivo animal models to investigate the role of BMDCs in tumor development are poorly explored. We established a novel chimeric mouse model using as low as 5
Autor:
Bhagelu R. Achyut, Ali S. Arbab, Kartik Angara, Alfonso G. Scicli, Peng Zeng, Robert A. Knight, Roxan Ara, Adarsh Shankar, A. S.M. Iskander
Publikováno v:
Cancer Letters. 369:416-426
Glioblastoma (GBM) is a hypervascular and malignant form of brain tumors. Anti-angiogenic therapies (AAT) were used as an adjuvant against VEGF-VEGFR pathway to normalize blood vessels in clinical and preclinical studies, which resulted into marked h
Autor:
Roxan Ara, A. S.M. Iskander, Mohammad H. Rashid, Bhagelu R. Achyut, Iryna Lebedyeva, Thaiz F. Borin, Ping Chang Lin, Kartik Angara, Roni J. Bollag, Ali S. Arbab
Publikováno v:
Neoplasia. 21:156-157
Glioblastoma (GBM) was shown to relapse faster and displayed therapeutic resistance to antiangiogenic therapies (AATs) through an alternative tumor cell-driven mechanism of neovascularization called vascular mimicry (VM). We identified highly upregul
Autor:
Mohammad H. Rashid, A. S.M. Iskander, Thaiz F. Borin, Bhagelu R. Achyut, Ravindra Kolhe, Ali S. Arbab, Paulo C. Rodriguez, Kartik Angara, Roxan Ara, Meenu Jain, Shelby Howard, Jennifer W. Bradford, Natasha Venugopal
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Tumor development and therapeutic resistance are linked with tumor-associated macrophage (TAM) and myeloid-derived suppressor cell (MDSC) infiltration in tumors via chemokine axis. Chemokine expression, which determines the pro or anti-inflammatory s
Autor:
Adarsh Shankar, A. S.M. Iskander, Marina Gobbe Moschetta, Debora Aparecida Pires de Campos Zuccari, Lívia Carvalho Ferreira, Juliana Garcia de Oliveira, Thaiz F. Borin, Vanessa Alves Fabri, Gabriela Bottaro Gelaleti, Nadimpalli Ravi S. Varma, Ali S. Arbab, Verena Benedick Coimbra, Bruna Victorasso Jardim-Perassi
Publikováno v:
Journal of pineal research. 60(1)
The occurrence of metastasis, an important breast cancer prognostic factor, depends on cell migration/invasion mechanisms, which can be controlled by regulatory and effector molecules such as Rho-associated kinase protein (ROCK-1). Increased expressi
Autor:
Adarsh Shankar, Meser M. Ali, L.C. Ferreira, Thaiz F. Borin, Ali S. Arbab, Nadimpalli Ravi S. Varma, Bruna Victorasso Jardim-Perassi, Debora Aparecida Pires de Campos Zuccari, A. S.M. Iskander
Publikováno v:
Anti-cancer agents in medicinal chemistry. 15(10)
The formation of a new blood vessel is stimulated by angiogenic factors. Curcumin, which is the active ingredient of the spice plant Curcuma longa L and is used as food and traditional medicine, has shown anticancer effects against different types of
Publikováno v:
IEEE Conference Record - Abstracts. PPPS-2001 Pulsed Power Plasma Science 2001. 28th IEEE International Conference on Plasma Science and 13th IEEE International Pulsed Power Conference (Cat. No.01CH37255).
Publikováno v:
IEE Symposium Pulsed Power 2001.
A new test fixture has highlighted important differences between the various classes of devices under forced de-saturation fault condition working. This paper discusses the latest test fixture, in particular how it is constructed and used. Results fr
Publikováno v:
IEE Symposium Pulsed Power 2000.
This paper examines the switching properties of IGBTs and other input controlled devices for driving thermionic devices. In particular, attention is drawn to the turn off behaviour under short pulse operation, with a load fault condition. Examination