Zobrazeno 1 - 10
of 329
pro vyhledávání: '"A. S. Zinkernagel"'
Autor:
Alejandro Gómez-Mejia, Mariano Orlietti, Andrea Tarnutzer, Srikanth Mairpady Shambat, Annelies S. Zinkernagel
Publikováno v:
mSphere, Vol 9, Iss 10 (2024)
ABSTRACT The human pathobiont Streptococcus pyogenes forms biofilms and causes infections, such as pharyngotonsillitis and necrotizing fasciitis. Bacterial biofilms are more resilient to antibiotic treatment, and new therapeutic strategies are needed
Externí odkaz:
https://doaj.org/article/090ca32e6e4142708f637e2585f22d53
Autor:
Nadia Keller, Mathilde Boumasmoud, Federica Andreoni, Andrea Tarnutzer, Manuela von Matt, Thomas C. Scheier, Jana Epprecht, David Weller, Alejandro Gómez-Mejia, Markus Huemer, Donata von Reibnitz, Duveken B. Y. Fontein, Ewerton Marques-Maggio, Reto A. Schuepbach, Srikanth Mairpady-Shambat, Silvio D. Brugger, Annelies S. Zinkernagel
Publikováno v:
mSphere, Vol 9, Iss 9 (2024)
ABSTRACT Group A Streptococcus (GAS) necrotizing fasciitis (NF) is a difficult-to-treat bacterial infection associated with high morbidity and mortality despite extensive surgery and targeted antibiotic treatment. Difficult-to-treat infections are of
Externí odkaz:
https://doaj.org/article/a3445359d53a4465884d6865a96d6df4
Autor:
Lorenzo Ferro Desideri, Rodrigo Anguita, Lieselotte E. Berger, Helena M. A. Feenstra, Davide Scandella, Raphael Sznitman, Camiel J. F. Boon, Elon H. C. van Dijk, Martin S. Zinkernagel
Publikováno v:
International Journal of Retina and Vitreous, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Aim To adopt a novel artificial intelligence (AI) optical coherence tomography (OCT)-based program to identify the presence of biomarkers associated with central serous chorioretinopathy (CSC) and whether these can differentiate between acut
Externí odkaz:
https://doaj.org/article/5242f88c97b64a93bb849fbb4a4da208
Autor:
Federica M. Conedera, Despina Kokona, Martin S. Zinkernagel, Jens V. Stein, Charles P. Lin, Clemens Alt, Volker Enzmann
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Retinal degeneration results from disruptions in retinal homeostasis due to injury, disease, or aging and triggers peripheral leukocyte infiltration. Effective immune responses rely on coordinated actions of resident microglia and
Externí odkaz:
https://doaj.org/article/916c1fd49e544c4fb67ae384fc06888f
Publikováno v:
BMJ Open Ophthalmology, Vol 9, Iss 1 (2024)
Background/aims This study reports on the long-term functional and anatomical outcomes of patients with central retinal vein occlusion (CRVO) treated under the Bern treat-and-extend (T&E) protocol.Methods Observational study. Treatment-naive patients
Externí odkaz:
https://doaj.org/article/894698c941134718b70576f4f0ec74f7
Autor:
Pascal Aurel Gubser, Valentin Pfeiffer, Simon Hug, Xiao Shang, Joel-Benjamin Lincke, Nathanael Urs Häner, Martin S. Zinkernagel, Jan Darius Unterlauft
Publikováno v:
Eye and Vision, Vol 10, Iss 1, Pp 1-12 (2023)
Abstract Background To compare the intermediate-term efficacy of PRESERFLO (PF) MicroShunt implantation with trabeculectomy (TE) in patients with primary open-angle glaucoma, focusing on longitudinal changes of functional and structural parameters. M
Externí odkaz:
https://doaj.org/article/cdc7d6c564094692acb72b4b94974aff
Autor:
Meng Tian, Guodong Zeng, Christoph Tappeiner, Martin S. Zinkernagel, Sebastian Wolf, Marion R. Munk
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/0f6936b9ef604b6da67e90a4b63e6624
Autor:
Livia Spörri, Anne-Christine Uldry, Marco Kreuzer, Elio L. Herzog, Martin S. Zinkernagel, Jan D. Unterlauft, Denise C. Zysset-Burri
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6257 (2024)
Although glaucoma is a leading cause of irreversible blindness worldwide, its pathogenesis is incompletely understood, and intraocular pressure (IOP) is the only modifiable risk factor to target the disease. Several associations between the gut micro
Externí odkaz:
https://doaj.org/article/8470a9edab8747c091bb14b814c11cd3
Autor:
Laura Marquardt, Federica Andreoni, Mathilde Boumasmoud, Tiziano A. Schweizer, Dorothea M. Heuberger, Elena Parietti, Sanne Hertegonne, Jana Epprecht, Dario Mattle, Anna K. Raez, Ewerton Marques‐Maggio, Reto A. Schuepbach, Barbara Hasse, Srikanth Mairpady‐Shambat, Silvio D. Brugger, Annelies S. Zinkernagel
Publikováno v:
MicrobiologyOpen, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Group A streptococcal (GAS; aka Streptococcus pyogenes) meningitis is a fulminant disease associated with high morbidity and mortality. To elucidate the mechanisms underlying the invasiveness of GAS in meningitis, we compared GAS isolates de
Externí odkaz:
https://doaj.org/article/f22407c14bca41b089746197c77dec28
Autor:
Christian Roehrig, Markus Huemer, Dominique Lorgé, Fabienne Arn, Nadine Heinrich, Lavanja Selvakumar, Lynn Gasser, Patrick Hauswirth, Chun-Chi Chang, Tiziano A. Schweizer, Fritz Eichenseher, Steffi Lehmann, Annelies S. Zinkernagel, Mathias Schmelcher
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Bacterial infections are a growing global healthcare concern, as an estimated annual 4.95 million deaths are associated with antimicrobial resistance (AMR). Methicillin-resistant Staphylococcus aureus is one of the deadliest pathogens and a
Externí odkaz:
https://doaj.org/article/49556bdc79fb40e0848bc9a5790f6e34