Zobrazeno 1 - 10
of 2 340
pro vyhledávání: '"A. S. Wilkinson"'
Autor:
Josephine E. Haddon, Daniel Titherage, Julia R. Heckenast, Jennifer Carter, Michael J. Owen, Jeremy Hall, Lawrence S. Wilkinson, Matthew W. Jones
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Impaired behavioural flexibility is a core feature of neuropsychiatric disorders and is associated with underlying dysfunction of fronto-striatal circuitry. Reduced dosage of Cyfip1 is a risk factor for neuropsychiatric disorder, as evidence
Externí odkaz:
https://doaj.org/article/ff9feaf84b2d4dadb10bfac41d15a835
Autor:
Courtney S. Wilkinson, Harrison L. Blount, Shane Davis, Giselle Rojas, Lizhen Wu, Niall P. Murphy, Marek Schwendt, Lori A. Knackstedt
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Opioid-alcohol polysubstance use is prevalent and worsens treatment outcomes. Here we assessed whether co-consumption of oxycodone and alcohol influence the intake of one another, demand for oxycodone, and the neurocircuitry underlying cue-p
Externí odkaz:
https://doaj.org/article/5f92b4f2f79e4a2a9510606116d19623
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0298717 (2024)
Loss of function (LoF) mutations affecting the histone methyl transferase SETD1A are implicated in the aetiology of a range of neurodevelopmental disorders including schizophrenia. We examined indices of development and adult behaviour in a mouse mod
Externí odkaz:
https://doaj.org/article/eb3b3a06bced421e9ae528b61631e47c
Autor:
Heather M. Chick, Megan E. Rees, Matthew L. Lewis, Lisa K. Williams, Owen Bodger, Llinos G. Harris, Steven Rushton, Thomas S. Wilkinson
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 724 (2024)
Whole blood models are rapid and versatile for determining immune responses to inflammatory and infectious stimuli, but they have not been used for bacterial discrimination. Staphylococcus aureus, S. epidermidis and Escherichia coli are the most comm
Externí odkaz:
https://doaj.org/article/46e1fbc0d41d4413a90fa0d93bd2b3c7
Autor:
Scott Brown, Stephen J. Evans, Michael J. Burgum, Kirsty Meldrum, Jack Herridge, Blessing Akinbola, Llinos G. Harris, Rowena Jenkins, Shareen H. Doak, Martin J. D. Clift, Thomas S. Wilkinson
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 128 (2024)
The exposure of human lung and skin to carbon black (CB) is continuous due to its widespread applications. Current toxicological testing uses ‘healthy’ cellular systems; however, questions remain whether this mimics the everyday stresses that hum
Externí odkaz:
https://doaj.org/article/1d088c9d6c3e4db789994203ea74b278
Publikováno v:
Results in Physics, Vol 49, Iss , Pp 106526- (2023)
An analytical theoretical model for the waveguide grating coupler is developed and applicable to practical deep gratings. The grating-assisted input coupling efficiency is calculated by considering the reciprocal out-coupling problem. The deep gratin
Externí odkaz:
https://doaj.org/article/f8204b55a05d492baaba0e9345b266ed
Autor:
Sheridan L. Swan, Nalini Mehta, Ekaterina Ilich, Steven H. Shen, Daniel S. Wilkinson, Alexa R. Anderson, Tatiana Segura, Luis Sanchez-Perez, John H. Sampson, Ravi V. Bellamkonda
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Chimeric antigen receptor (CAR) T cell therapy in glioblastoma faces many challenges including insufficient CAR T cell abundance and antigen-negative tumor cells evading targeting. Unfortunately, preclinical studies evaluating CAR T cells in glioblas
Externí odkaz:
https://doaj.org/article/4a7e6f834a8743eb94562f47d06d7da9
Autor:
Mohamed A Ettabib, Bethany M Bowden, Zhen Liu, Almudena Marti, Glenn M Churchill, James C Gates, Michalis N Zervas, Philip N Bartlett, James S Wilkinson
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0284058 (2023)
We report a waveguide-enhanced Raman spectroscopy (WERS) platform with alignment-tolerant under-chip grating input coupling. The demonstration is based on a 100-nm thick planar (slab) tantalum pentoxide (Ta2O5) waveguide and the use of benzyl alcohol
Externí odkaz:
https://doaj.org/article/c9845ffb0ed14c609b3a1aa994fe3064
Autor:
E. J. Marjanovic, V. Sharma, L. Smith, C. Pinder, T. L. Moore, J. B. Manning, G. Dinsdale, M. Berks, V. L. Newton, S. Wilkinson, M. R. Dickinson, A. L. Herrick, R. E. B. Watson, A. K. Murray
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Polarisation-sensitive optical coherence tomography (PS-OCT) offers a novel, non-invasive method of assessing skin fibrosis in the multisystem disease systemic sclerosis (SSc) by measuring collagen retardance. This study aimed to assess reta
Externí odkaz:
https://doaj.org/article/24850a55cf7c45249861cbee7d2c202a
Publikováno v:
Frontiers in Education, Vol 7 (2022)
BackgroundThe use of simulations has been steadily rising in popularity in the biosciences, not only due to the COVID-19 pandemic restricting access to physical labs and equipment but also in the face of rising student numbers. In this study, we desc
Externí odkaz:
https://doaj.org/article/a57e2e2abf2a4d08a54707622bfba67e