Zobrazeno 1 - 10
of 46
pro vyhledávání: '"A. S. Unis"'
Autor:
Ed Goldson, Jeffrey Munson, Alan S. Unis, Robin L. Gabriels, Sally J. Rogers, Geraldine Dawson, Julie Osterling, Robert D. Abbott
Publikováno v:
Journal of the American Academy of Child & Adolescent Psychiatry. 41:1315-1321
Objective: To compare the effects of a single dose of biologic and synthetic porcine secretin to placebo on a variety of autism symptoms. Method: Eighty-five children with autism without other medical conditions and not taking other psychotropic medi
Publikováno v:
Journal of Child Neurology. 16:849-853
Neurogenesis and neuronal differentiation are determined by the NeuroD homologues, transcription factors belonging to a family of basic helix-loop-helix proteins. The authors used in situ hybridization with full-length riboprobes for NeuroD1, NeuroD2
Autor:
C. M. Yates, William D. Graf, S. Sulzbacher, K. A. Dugaw, W. W. Parson, R. M. Jack, M. B. Dinulos, M. N. Paddock, A. S. Unis
Publikováno v:
Neurology. 57:410-416
Objective:To investigate catecholamine phenotypes and the effects of a tyrosine hydroxylase inhibitor in individuals with the 22q11.2 deletion syndrome and low-activity catechol-O-methyltransferase (COMT).Background:Many persons with the 22q11.2 dele
Publikováno v:
Developmental Brain Research. 127:123-133
Glutamate receptors have multiple roles in the central nervous system. Recent evidence suggests that the iontropic glutamate receptors are critical during brain development, particularly for corticogenesis, neuronal migration, and synaptogenesis. In
Autor:
Alan S. Unis, Y John C. Rose
Publikováno v:
The American Journal of Emergency Medicine. 18:176-179
The rate of introduction of new pharmaceuticals is growing as a result of advances in molecular pharmacology and targeted drug development. The Fatal Toxicity Index (FTI) has been proposed as a means for monitoring drug toxicity through post-marketin
Publikováno v:
Developmental Brain Research. 106:109-117
Dopamine receptor expression in human fetal forebrain (between 6 and 20 weeks of gestation) was measured using tissue-slice receptor autoradiography with the D1-like and D2-like antagonists [3H]-SCH23390 and [3H]-YM09151-2, respectively. Tissue secti
Publikováno v:
Peptides. 18:527-535
Haloperidol is believed to induce neurotensin/neuromedin N (NT/ N) gene expression in the dorsolateral striatum (DLST) of the rat brain via dopamine D2 receptor blockade, but is also known to interact with other receptors as well. To further characte
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 19:333-342
1. 1. Striatal D 2 receptor concentration (as determined by [ 3 H]-spiperone binding to brain tissue homogenates) has been correlated, in F344 rats, with a number of locomotor behaviors (e.g. response latency on conditioned avoidance and decreased op
Autor:
Alan S. Unis
Publikováno v:
Biological Psychiatry. 35:562-569
In order to determine the gestational age at which binding sites for the dopamine "D 1 -like" and "D 2 -like" receptor antagonists, [ 3 H]-SCH23390 and [ 3 H]-YM09151-2, respectively, can be reliably detected in the human and to identify any discrete
Publikováno v:
Journal of child and adolescent psychopharmacology. 20(6)
Atypical antipsychotic drugs are prescribed to young children for a number of symptoms, some with no Food and Drug Administration approval for children. Effects on growth of children have received little experimental study. We assessed the effects of