Zobrazeno 1 - 10
of 534
pro vyhledávání: '"A. S. McNeilly"'
Autor:
S. H. Wood, M. M. Hindle, Y. Mizoro, Y. Cheng, B. R. C. Saer, K. Miedzinska, H. C. Christian, N. Begley, J. McNeilly, A. S. McNeilly, S. L. Meddle, D. W. Burt, A. S. I. Loudon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
“Life in a seasonal environment requires appropriate timing of physiological changes to survive, but how the circadian clockwork times these changes remains unclear. Here the authors show that the circadian clock genes BMAL2 and DEC1, in concert wi
Externí odkaz:
https://doaj.org/article/7fb5add7468b4e49b866c4366595cefd
Autor:
Karen Featherstone, Kirsty Hey, Hiroshi Momiji, Anne V McNamara, Amanda L Patist, Joanna Woodburn, David G Spiller, Helen C Christian, Alan S McNeilly, John J Mullins, Bärbel F Finkenstädt, David A Rand, Michael RH White, Julian RE Davis
Publikováno v:
eLife, Vol 5 (2016)
Transcription at individual genes in single cells is often pulsatile and stochastic. A key question emerges regarding how this behaviour contributes to tissue phenotype, but it has been a challenge to quantitatively analyse this in living cells over
Externí odkaz:
https://doaj.org/article/4711de80f72b4aca95bc49e34466bac3
Autor:
Fiona Connolly, Michael T Rae, Mairead Butler, Alexander L Klibanov, Vassilis Sboros, Alan S McNeilly, W Colin Duncan
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111280 (2014)
In order to develop a medical alternative to surgical ovarian diathermy (OD) in polycystic ovary syndrome (PCOS) more mechanistic information is required about OD. We therefore studied the cellular, molecular and vascular effects of diathermy on the
Externí odkaz:
https://doaj.org/article/5551d1975b0a4a68996b58dc680046cc
Autor:
Helen C. Christian, Andrew S. I. Loudon, Matthew Hindle, Yasutaka Mizoro, Dave Burt, Ben Saer, Shona H. Wood, Judith McNeilly, Alan S. McNeilly, Yung Sung Cheng, Katarzyna Miedzinska, Simone Meddle, Nicola Begley
Publikováno v:
Wood, S, Hindle, M, Mizoro, Y, Cheng, Y, Saer, B, Miedzinska-Bielecka, K, Christian, H, Begley, N, J, M, McNeilly, A, Meddle, S, Burt, D & Loudon, A 2020, ' Circadian clock mechanism driving mammalian photoperiodism. ', Nature Communications, vol. 11, 4291 (2020), pp. 1-15 . https://doi.org/10.1038/s41467-020-18061-z
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Wood, S, Hindle, M M, Mizoro, Y, Cheng, Y, Saer, B, Miedzinska, K, Christian, H C, Begley, N, McNeilly, J, McNeilly, A S, Meddle, S L, Burt, D W & Loudon, A 2020, ' Circadian clock mechanism driving mammalian photoperiodism ', Nature Communications, vol. 11, 4291 . https://doi.org/10.1038/s41467-020-18061-z
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Wood, S, Hindle, M M, Mizoro, Y, Cheng, Y, Saer, B, Miedzinska, K, Christian, H C, Begley, N, McNeilly, J, McNeilly, A S, Meddle, S L, Burt, D W & Loudon, A 2020, ' Circadian clock mechanism driving mammalian photoperiodism ', Nature Communications, vol. 11, 4291 . https://doi.org/10.1038/s41467-020-18061-z
The annual photoperiod cycle provides the critical environmental cue synchronizing rhythms of life in seasonal habitats. In 1936, Bünning proposed a circadian-based coincidence timer for photoperiodic synchronization in plants. Formal studies suppor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe68ec4d59282f4ea3b26b1fb3be070
https://hdl.handle.net/20.500.11820/5e075f9c-9115-4113-8aa7-1d78e2ed165d
https://hdl.handle.net/20.500.11820/5e075f9c-9115-4113-8aa7-1d78e2ed165d
Autor:
A S McNeilly, D T Baird
Publikováno v:
Bioscientifica Proceedings.
In the adult non-pregnant ewe the secretion of FSH is sufficient to ensure a continuous growth and development of antral follicles to 3-5 mm size at all times. Further development and increased secretion of oestradiol through the final 72 h to ovulat
Role of GnRH in the ontogeny and regulation of the fetal hypothalamo-pituitary-gonadal axis in sheep
Publikováno v:
Bioscientifica Proceedings.
Adult reproductive ability is to a large extent determined by the appropriate development of the reproductive axis during fetal life. Studies have investigated the role of the fetal hypothalamus in the ontogeny and regulation of pituitary gonadal fun
Publikováno v:
Bioscientifica Proceedings.
In the sheep both FSH and LH are necessary for development of large antral follicles. The secretion of FSH is controlled by the negative feedback effect of two ovarian hormones, oestradiol and inhibin, acting at the level of the anterior pituitary. B
Publikováno v:
Bioscientifica Proceedings.
Publikováno v:
Bioscientifica Proceedings.
Preovulatory follicle growth in the ewe is dependent on FSH although no precise relationship appears to exist between plasma concentrations of FSH and the number of preovulatory follicles which develop or ovulation rate. This may be related to a hith
Publikováno v:
Bioscientifica Proceedings.
The Booroola phenotype is associated with a point mutation in the kinase domain of the bone morphogenetic protein receptor 1 B (BMPR1 B), and is characterized by 'precocious' differentiation of ovarian follicles, leading to the production of large nu