Evidence-Informed Approach to De-Prescribing of Atypical Antipsychotics (AAP) in the Management of Behavioral Expressions (BE) in Advanced Neurocognitive Disorders (NCD): Results of a Retrospective Study

Autor: A. S. Luthra, R. LinBin Gao, P. Carducci, J. Sue, S. Remers

Publikováno v: European Psychiatry, Vol 67, Pp S68-S69 (2024)

Introduction Diagnosis of behaviors in advanced neurocognitive disorders (aNCD) is one of exclusion, and the framework has been laid out in DSM-V. However, clinical assessments in aNCD become increasingly unreliable, and commonly used psychometric to

Externí odkaz: https://doaj.org/article/aa35e6d2cbb04114aeaeecff88f79815

Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation

Autor: Nijee S. Luthra, Kyle T. Mitchell, Monica M. Volz, Idit Tamir, Phillip A. Starr, Jill L. Ostrem

Publikováno v: Tremor and Other Hyperkinetic Movements, Vol 7 (2017)

Background: Blepharospasm can be present as an isolated dystonia or in conjunction with other forms of cranial dystonia, causing significant disability.Case Report: We report a case of a 69-year-old male with craniocervical dystonia, manifesting prim

Externí odkaz: https://doaj.org/article/29fc0d8b827b4f18a5cebc1ced1cf2d3

Memantine, Simvastatin, and Epicatechin Inhibit 7-Ketocholesterol-induced Apoptosis in Retinal Pigment Epithelial Cells But Not Neurosensory Retinal Cells In Vitro

Autor: A. Neekhra, Baruch D. Kuppermann, Kevin Schneider, M. Cristina Kenney, Julia Tran, Khoa Pham, Ashish Sharma, Parsa R Esfahani, Marilyn Chwa, Ana L. Gramajo, S. Luthra, Saffar Mansoor

Publikováno v: Journal of Ophthalmic & Vision Research, Vol 15, Pp 470-480 (2020)
Journal of Ophthalmic & Vision Research
Journal of ophthalmic & vision research, vol 15, iss 4

Purpose: 7-ketocholesterol (7kCh), a natural byproduct of oxidation in lipoprotein deposits is implicated in the pathogenesis of diabetic retinopathy and age-related macular degeneration (AMD). This study was performed to investigate whether several

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e083349a984555f71f565155679879ba
https://doaj.org/article/295d056fd3cc4cc0855f0b3f4cee8e80

Characterization of vitamin D supplementation and clinical outcomes in a large cohort of early Parkinson’s disease

Autor: Nijee S. Luthra, Soeun Kim, Yunxi Zhang, Chadwick W. Christine, On behalf of the NINDS NET-PD Investigators

Publikováno v: Journal of Clinical Movement Disorders, Vol 5, Iss 1, Pp 1-5 (2018)
Journal of clinical movement disorders, vol 5, iss 1
Journal of Clinical Movement Disorders

BackgroundVitamin D (VitD) deficiency is common in Parkinson's disease (PD) and has been raised as a possible PD risk factor. In the past decade, VitD supplementation for potential prevention of age related conditions has become more common. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5230f8355ebfbbb49626ffde0749ba35
http://link.springer.com/article/10.1186/s40734-018-0074-6

Suppression of Inflammatory Arthritis by Human Gut-DerivedPrevotella histicolain Humanized Mice

Autor: Patricio Jeraldo, Robin Patel, Joseph A. Murray, David Luckey, Ashutosh K. Mangalam, Veena Taneja, Harvinder S. Luthra, Eric V. Marietta, Abhinav Lamba

Publikováno v: Arthritis & Rheumatology. 68:2878-2888

Objective The gut microbiome regulates host immune homeostasis. Rheumatoid arthritis (RA) is associated with intestinal dysbiosis. This study was undertaken to test the ability of a human gut-derived commensal to modulate immune response and treat ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::107566bd23a9c1e2ffe82039e94008bb
https://doi.org/10.1002/art.39785