Zobrazeno 1 - 10
of 65
pro vyhledávání: '"A. S. Lobachev"'
Publikováno v:
Nucleic Acids Research. 51:3722-3734
DNA inverted repeats (IRs) are widespread across many eukaryotic genomes. Their ability to form stable hairpin/cruciform secondary structures is causative in triggering chromosome instability leading to several human diseases. Distance and sequence d
Recording the Onset of Detonation in the Depth of an Explosive by X-ray and Electric Contact Methods
Autor:
A. R. Akhmetov, V. G. Poleev, O. A. Nikitin, A. A. Kargin, S. M. Ul’yanov, M. Yu. Stolbikov, A. S. Lobachev, R. V. Protas, D. A. Starostenko
Publikováno v:
Физика горения и взрыва. 58:118-126
Autor:
Basanta K Dahal, Lyudmila Y Kadyrova, Kristin R Delfino, Igor B Rogozin, Vaibhavi Gujar, Kirill S Lobachev, Farid A Kadyrov
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007074 (2017)
Heterochromatin contains a significant part of nuclear DNA. Little is known about the mechanisms that govern heterochromatic DNA stability. We show here that in the yeast Saccharomyces cerevisiae (i) DNA mismatch repair (MMR) is required for the main
Externí odkaz:
https://doaj.org/article/3715eea6da3241f6829b4f7ed5959833
Autor:
Kirill S. Lobachev, Ziwei Sheng, Alex B Costa, Wenying Guo, Anissia Ait Saada, James E. Haber
Publikováno v:
Nucleic Acids Research
Palindromic sequences are a potent source of chromosomal instability in many organisms and are implicated in the pathogenesis of human diseases. In this study, we investigate which nucleases are responsible for cleavage of the hairpin and cruciform s
Positive and counter-selectable markers have been successfully integrated as a part of numerous genetic assays in many model organisms. In this study, we investigate the mechanism of resistance to arginine analog canavanine and its applicability for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c164b6be988052ae25622136e64bd1a4
https://doi.org/10.1101/2022.03.11.484000
https://doi.org/10.1101/2022.03.11.484000
Autor:
Anita Salamon, Kirill S. Lobachev, Karol Szlachta, Heather M Raimer, Arkadi Manukyan, Yuh-Hwa Wang, Wenying Guo, Sandeep Singh
Publikováno v:
Nucleic Acids Research
DNA double-stranded breaks (DSBs) trigger human genome instability, therefore identifying what factors contribute to DSB induction is critical for our understanding of human disease etiology. Using an unbiased, genome-wide approach, we found that gen
Autor:
E. V. Kashtanova, A. S. Lobacheva
Publikováno v:
Вестник университета, Vol 0, Iss 3, Pp 176-185 (2024)
The article is devoted to the study of the genesis of understanding the causes of bias and discrimination of human capital from traditional forms to the era of digitalisation and artificial intelligence (hereinafter referred to as AI). In this articl
Externí odkaz:
https://doaj.org/article/62e1cf8cf3694c7694fff6135a12e14a
Publikováno v:
PLOS ONE. 17:e0269276
Positive and counter-selectable markers have been successfully integrated as a part of numerous genetic assays in many model organisms. In this study, we investigate the mechanism of resistance to arginine analog canavanine and its applicability for
Autor:
Natalie Saini, Yu Zhang, Yuri Nishida, Ziwei Sheng, Shilpa Choudhury, Piotr Mieczkowski, Kirill S Lobachev
Publikováno v:
PLoS Genetics, Vol 9, Iss 6, p e1003551 (2013)
DNA sequences capable of adopting non-canonical secondary structures have been associated with gross-chromosomal rearrangements in humans and model organisms. Previously, we have shown that long inverted repeats that form hairpin and cruciform struct
Externí odkaz:
https://doaj.org/article/b552422e4c7d4c6bb6dc8d5f5db6fecd
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1003979 (2013)
Inverted repeats capable of forming hairpin and cruciform structures present a threat to chromosomal integrity. They induce double strand breaks, which lead to gross chromosomal rearrangements, the hallmarks of cancers and hereditary diseases. Second
Externí odkaz:
https://doaj.org/article/7f73194a723847e3a0afecd641bb84e4