Zobrazeno 1 - 10 of 348 pro vyhledávání: '"A. S. Lea"'
3
Akademický článek
Identification of PARP-7 substrates reveals a role for MARylation in microtubule control in ovarian cancer cells
Autor: Lavanya H Palavalli Parsons, Sridevi Challa, Bryan A Gibson, Tulip Nandu, MiKayla S Stokes, Dan Huang, Jayanthi S Lea, W Lee Kraus
Publikováno v: eLife, Vol 10 (2021)
PARP-7 (TiPARP) is a mono(ADP-ribosyl) transferase whose protein substrates and biological activities are poorly understood. We observed that PARP7 mRNA levels are lower in ovarian cancer patient samples compared to non-cancerous tissue, but PARP-7 p
Externí odkaz: https://doaj.org/article/a58e7e7a531844d7baa4e600daedecdb
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6
Akademický článek
Practice patterns using minimally invasive surgery for the treatment of ovarian cancer: A survey of physician members of the Society of Gynecologic Oncologists
Autor: Kevin M. Kremer, Jessica Lee, Matthew J. Carlson, Salvatore J. Lococo, David S. Miller, Jayanthi S. Lea
Publikováno v: Gynecologic Oncology Reports, Vol 33, Iss , Pp 100617- (2020)
Retrospective studies suggest that minimally-invasive surgery may be safe and effective for the treatment of early-stage ovarian cancer as well as interval cytoreduction after neoadjuvant chemotherapy. Adoption rates and attitudes towards its use rem
Externí odkaz: https://doaj.org/article/b38a3890b5594f9e87165426cb8754c1
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7
Akademický článek
Sparse feature selection for classification and prediction of metastasis in endometrial cancer
Autor: Mehmet Eren Ahsen, Todd P. Boren, Nitin K. Singh, Burook Misganaw, David G. Mutch, Kathleen N. Moore, Floor J. Backes, Carolyn K. McCourt, Jayanthi S. Lea, David S. Miller, Michael A. White, Mathukumalli Vidyasagar
Publikováno v: BMC Genomics, Vol 18, Iss S3, Pp 1-12 (2017)
Abstract Background Metastasis via pelvic and/or para-aortic lymph nodes is a major risk factor for endometrial cancer. Lymph-node resection ameliorates risk but is associated with significant co-morbidities. Incidence in patients with stage I diseas
Externí odkaz: https://doaj.org/article/5685153e23b84181b171b36625789c9b
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8
Akademický článek
The complete mitochondrial genome of a gray reef shark, Carcharhinus amblyrhynchos (Carcharhiniformes: Carcharhinidae), from the Western Indian Ocean
Autor: Ela Patel, Andrea M. Bernard, Marissa Mehlrose, Sydney Harned, Kimberly A. Finnegan, Cristín K. Fitzpatrick, James S. Lea, Mahmood S. Shivji
Publikováno v: Mitochondrial DNA. Part B. Resources, Vol 5, Iss 3, Pp 3498-3499 (2020)
We present the mitochondrial genome sequence of a gray reef shark, Carcharhinus amblyrhynchos (Bleeker 1856), a coral reef associated species. This is the first mitogenome for this species from the western Indian Ocean. The mitogenome is 16,705 bp in
Externí odkaz: https://doaj.org/article/ae629ee21f3e44169507c107e001f59c
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10
Combinatorial Treatment with PARP-1 Inhibitors and Cisplatin Attenuates Cervical Cancer Growth through Fos-Driven Changes in Gene Expression
Autor: Rebecca Gupte, Ken Y. Lin, Tulip Nandu, Jayanthi S. Lea, W. Lee Kraus
Publikováno v: Molecular Cancer Research. 20:1183-1192
Cervical cancer continues to be a significant cause of cancer-related deaths in women. The most common treatment for cervical cancer involves the use of the drug cisplatin in conjunction with other therapeutics. However, the development of cisplatin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b26af3dd27bceab5f535095f2c6d65ca
https://doi.org/10.1158/1541-7786.mcr-22-0111
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